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Wayne C Guida
Professor

University of South Florida

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Recent Publications:
1.   “A computational design approach for virtual sreening of peptide interactions across K(+) channel families. Doupnik CA, Parra KC,Guida WC.  Comput Struct Biotechnol J., 2014, 13, 85.
 
2.   Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium. 2: Cross RM, Flanigan DL, Monastyrskyi A, LaCrue AN, Sáenz FE, Maignan JR, Mutka TS, White KL, Shackleford DM, Bathurst I, Fronczek FR, Wojtas L, Guida WC, Charman SA, Burrows JN, Kyle DE, Manetsch R. J Med Chem. 2014, 57, 8860.
 
3.   “Plasmodium vivax 1-deoxy-D-xylulose-5-phosphate synthase: Homology Modeling, Domain Swapping, and Virtual Screening.” Ramamoorthy DHanda S, Merkler DJ, Guida WCJ Data Mining Genomics Proteomics, 2014, S1:003. doi:10.4172/2153-0602.S1-003.
 
4.   “Virtual target screening to rapidly identify potential protein targets of natural products in drug discovery.” Pevzner YSantiago DNSalm JLMetcalf RS, Daniel KG, Calcul Woodcock HL, Baker BJ, Guida WC, Brooks WH. AIMS Molecular Science, 2014, 1, 81.
 
5.   “Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.” Cross RM, Flanigan DL, Monastyrskyi A, LaCrue AN, Sáenz FE, Maignan JR, Mutka TS, White KL, Shackleford DM, Bathurst I, Fronczek FR, Wojtas L, Guida WC, Charman SA, Burrows JN, Kyle DE, Manetsch R. J Med Chem., 2014, 57, 8860. PMID: 25148516.
 
6.   “In silico characterization of an atypical MAPK phosphatase of Plasmodium falciparum as a suitable target for drug discovery.” Campbell CO, Santiago DNGuida WC, Manetsch R, Adams JH. Chem Biol Drug Des., 2014, 84, 158. PMID: 24605883.
 
7.   “Development of new N-Arylbenzamides as STAT3 Dimerization Inhibitors.” Urlam MK, Pireddu R, Ge Y, Zhang X, Sun Y, Lawrence HR, Guida WC, Sebti SM, Lawrence NJ.Medchemcomm., 2013, 4, 932-941. PMID: 24073326.
 
8.   “Identification of a New Binding Site in E. coli FabH using Molecular Dynamics Simulations: Validation by Computational Alanine Mutagenesis and Docking Studies.” Ramamoorthy D, Turos E, Guida WC. J Chem Inf Model. 2013, 53,1138-1156. PMID:23581389.
9.   “A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformation.” Zhang X, Sun Y, Pireddu R, Yang H, Urlam MK, Lawrence HR,Guida WC, Lawrence NJ, Sebti SM. Cancer Res., 2013,73,1922-1933. PMID: 23322008.
 

 

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