U.S. Patents (20)
5,000,000 Ethanol Production by Escherichia coli Strains Co-expressing Zymomonas pdc and adh Genes, L.O. Ingram, F. Alterthum, T. Conway (1991)
5,028,539 Ethanol Production using Engineered Mutant Escherichia coli, L.O. Ingram and
D.C. Clark (1992)
5,162,516 Cloning and Sequencing of the Alcohol Dehydrogenase II from Zymomonas
mobilis, L.O. Ingram and T. Conway (1992)
5,424,202 Ethanol Production by Recombinant Hosts, L. O. Ingram, D. S. Beall, G. F. H.
Burchhardt, W.V. Guimaraes, K. Ohta, B. E. Wood, K. T. Shanmugam, D.E. Fowler, A.
Ben-Bassat (1995)
5,482,846 Ethanol Production by Gram-Positive Microbes, L.O. Ingram and M.D.F. Barbosa-
Alleyne (1996).
5,602,030 Recombinant Glucose Uptake System, L.O. Ingram, N. Arfman, and J. Snoep
(1997).
5,821,093 Recombinant cells that highly express chromosomally-integrated heterologous
genes, L. O. Ingram, K. Ohta, and Brent E. Wood (1998).
5,916,787 Ingram, L.O. and M.D.F. Barbosa-Alleyne. Ethanol production in gram-positive
microbes (1999).
6,102,690 L.O. Ingram, X. Lai, M. Moniruzzaman and S.W. York. Recombinant organisms
capable of fermenting cellobiose (2000).
6,107,093 Recombinant cells that highly express chromosomally-integrated heterologous
genes. L. O. Ingram, K. Ohta, and B. E. Wood (2000).
6,130,076 Ethanol production using a soy hydrolysate-based medium or a yeast autolysate-
based medium. L.O. Ingram and S.W. York. (2000).
6,333,181 Ethanol production from lignocellulose. B.E. Wood and L.O. Ingram (2001).
6,849,434 Ethanol production in recombinant hosts. L.O. Ingram and M.D.F. Barbosa- Alleyne (2005)
7,026,152 Method and compositions for simultaneous saccharification and
fermentation. LO Ingram and S. Zhou. (2006)
7,098,009 Production of chemicals from lignocellulose, biomass, or sugars. K.T.
Shanmugam, L.O. Ingram, M.A. Patel, M.S. Ou, R. Harbucker(2006)
7,192,772 Recombinant cells that highly express chromosomally-integrated heterologous
Gene. Ingram LO, K Ohta, and BE Wood (2007)
7,226,776 Recombinant hosts suitable for simultaneous saccharification and fermentation.
Ingram, LO, and S Zhou (2007)
7,323,551 Cloning and sequencing of pyruvate decarboxylase (PDC) genes from bacteria
and uses therefor. Maupin-Furlow, JA, LA Talarico, RK Chandra and LO Ingram
(2008)
7,629,162 Materials and Methods for Efficient Lactic Acid Production. S. Zhou, L.O. Ingram, K.T.
Shanmugam, L.P. Yomano, T.B. Grabar, and J.C. Moore (Dec 2009)
7,977,075 Materials and Methods for the Efficient Production of Acetate and Other Products.
L.O. Ingram, T.B. Causey, S. Zhou, and K.T. Shanmugam. (7/12/2011)
8,124,259 Enhanced electrical contact to microbes in microbial fuel cells.
A. Rinzler, L.O. Ingram, J.C. Moore, Z. Wu, K.T. Shanmugam (2/28/2012)
Book Chapters and Reviews (25)
25. Jarboe, L.R.,P. Liu, K. Kautharapu, L.O. Ingram. 2012. Optimization of enzyme parameters for fermentative production of biorenewable fuels and chemicals. Computational and Structural Biotechnology Journal. October 2012. 3(4) e201210005, Mini Review Article http://dx.doi.org/10.5936/csbj.201210005
Chapter 17. Methods Mol Biol 581: 263-80.
22. Jarboe, L.R., K.T. Shanmugam, L.O. Ingram. 2009 Ethanol Encyclopedia of Microbiology (3rd Ed) Ed. D. Majumder-Russell. Elsevier
21. Luli, G.W., L.R. Jarboe, L.O. Ingram. 2008. “The development of ethanologenic bacteria for fuel ethanol production”. Bioenergy. 129-137.
18. Jarboe, L.R., T.B. Grabar, L.P. Yomano, K.T. Shanmugam, L.O. Ingram. 2007. Development of ethanologenic bacteria. Book Chapter. Adv. Biochem Engin/Biotechnol 108: 237-261. http://www.springerlink.com/content/w34780x4t1gxrp55/
17. Ingram, L.O., H.C. Aldrich, A.C.C. Borges, T.B. Causey, A. Martinez, F. Morales, A. Saleh, S.B. Underwood, L.P. Yomano, S.W. York, J. Zaldivar, and S. Zhou. 1999. Enteric bacterial catalysts for fuel ethanol production. Biotechnol. Prog. 15: 855-866.
16. Moniruzzaman, M. and L.O. Ingram. 1998. Ethanol production from dilute acid hydrolysate of rice hulls using genetically engineered Escherichia coli. Biotechnology Letters 20: 943-947.
15. Ingram, L.O., P.F. Gomez, X. Lai, M. Moniruzzaman, B.E. Wood, L.P. Yomano, and S.W.York. 1998. Metabolic Engineering of bacteria for ethanol production. Biotechnology and Bioengineering 58:204-214.
14. Ingram, L.O., X. Lai, M. Moniruzzaman, B.E. Wood, and S.E. York. 1997. Fuel ethanol production from lignocellulose using genetically engineered bacteria. In B.C. Saha and J. Woodward (eds.), Fuels and Chemicals from Biomass. ACS Symposium Series 666,
p. 57-73. American Chemical Society Press, Washington, D.C.
13. L.O. Ingram and J.B. Doran. 1995. Conversion of cellulosic materials to ethanol, FEMS Microbiol. Rev. 16: 235-241.
12. L.O. Ingram, R.J. Bothast, J.B. Doran, D.S. Beall, T.A. Brooks, B.E. Wood, X. Lai, K. Asghari, and L.P. Yomano. 1995. Genetic Engineering of Bacteria for the Conversion of Lignocellulose to Ethanol. In J.I. Burke and B. Rice (eds.), Proc. of the Workshop on Energy from Biomass and Waste, pp. 54-74. Teagasc, Oak Park Research Center, Carlow, Ireland.
11. L.O. Ingram. 1992. Genetic engineering of novel bacteria for the conversion of plant polysaccharides into ethanol. In M.R. Ladisch and A. Bose (ed), Harnessing Biotechnology for the 21st Century, p. 507-509. American Chemical Society Press, Washington, D.C.
10. L.O. Ingram. 1990. Ethanol tolerance in bacteria. Critical Rev. Biotechnology 9:305-319. Also listed in Reviews
9. L.O. Ingram, F. Alterthum, K. Ohta, and D.S. Beall. 1990. Genetic engineering of Escherichia coli and other enterobacteria for ethanol production, Developments in Industrial Microbiology, vol. 31, p. 21-30.
8. L.O. Ingram, K. Ohta, and D.S. Beall. 1990. Genetic modification of Escherichia coli for ethanol production, Energy from Biomass and Waste XIV (Don Klass, ed., Inst. Gas Technol. Chicago), p. 1105-1126.
7. L.O. Ingram and K.M. Dombek. 1989. Effects of ethanol on Escherichia coli. In N. van Uden (ed.), Alcohol Toxicity in Yeasts and Bacteria, CRC Press. p. 227-238.
6. L.O. Ingram, Y.A. Osman, T. Conway and K.M. Dombek. 1989. Zymomonas mobilis: Effects of ethanol on fermentation. In N. van Uden (ed.), Alcohol Toxicity in Yeasts and Bacteria, CRC Press. p. 257-270.
5. L.O. Ingram, C.K. Eddy, K.F. Mackenzie, T. Conway, and F. Alterthum. 1989. Genetics of Zymomonas mobilis and ethanol production. Developments in Industrial Microbiology vol. 30, p. 53-69.
4. L.O. Ingram and K.M. Dombek. 1987. On the evolution of alcohol tolerance in microorganisms. In Perspectives in Biotechnology (Duarte and Archer, eds.). p. 131-138. Plenum Publishing Corp.
3. L.O. Ingram. 1986. Microbial tolerance to alcohols: Role of the cell membrane. Trends in Biotechnology 4:40-44.
2. L.O. Ingram, K.M. Dombek, and Y.A. Osman. 1986. A hypothesis for the evolution of microbial resistance to ethanol. Soc. Industr. Microbiol. News 36:8-11.
1. L.O. Ingram and T.M. Buttke. 1984. Effects of alcohols on micro-organisms. Advances in Microbial Physiology 25: 253-300.
Refereed Publications (227)
227. Geddes, C.C., M.T. Mullinnix, I.U. Nieves, R.W. Hoffman, W.J. Sagues, S.W. York,
K.T. Shanmugam, J.E. Erickson, W.E. Vermerris, L.O. Ingram. 2013. Seed train development for the fermentation of bagasse from sweet sorghum and sugarcane using a simplified fermentation process. Bioresource Technology 128 (2013) 716–724.
226. Cheng, Q., Z. Tong, L. Dempere, L.O. Ingram, L. Wang, J.Y. Zhu. 2012. Disk refining and ultrasonication treated sugarcane bagasse residues for poly (Vinyl alcohol) bio-composites. J. Polym Environ. 10pp. Published online on December 18, 2012.
225. Zheng H, Wang X, Yomano LP, Shanmugam KT, Ingram LO. 2012. Increase in furfural tolerance in ethanologenic Escherichia coli LY180 by plasmid-based expression of thyA. Appl Environ Microbiol. 78(12): 4346-52.
224. Sun Z, Do PM, Rhee MS, Govindasamy L, Wang Q, Ingram LO, Shanmugam KT. 2012. Amino acid substitutions at Glutamate-354 in dihydrolipoamide dehydrogenase of Escherichia coli lower the sensitivity of pyruvate dehydrogenase to NADH. Microbiology, 1350-1358.
223. Chow Virginia, Guang Nong, Franz J. St. John, John D. Rice, Ellen Dickstein, Olga Chertkov, David Bruce, Chris Detter, Thomas Brettin, James Han, Tanja Woyke, Sam Pitluck, Matt Nolan, Amrita Pati, Joel Martin, Alex Copeland, Miriam L. Land, Lynne Goodwin, Jeffrey B. Jones, Lonnie O. Ingram, Keelnathan T. Shanmugam, and James F. Preston. 2012. Complete genome sequence of Paenobacillus sp. Strain JDR-2. Standards in Genomic Sciences. 6:1-10.
222. Wang X, Miller EN, Yomano LP, Shanmugam KT, Ingram LO. 2012. Increased furan-tolerance in Escherichia coli due to a cryptic ucpA gene. Appl Environ Microbiol. 78(7):2452-5.
221. Rhee, M.S., B.E. Moritz, G. Xie, T.G. del Rio, E. Dalin, H. Tice, D. Bruce, L. Goodwin, O. Chertkov, T. Brettin, C. Han, C. Detter, S. Pitluck, M.L. Land, M. Patel, M. Ou, R. Harbucker, L.O. Ingram, K.T. Shamugam. 2011. Complete genome sequence of a thermotolerant sporogenic lactic acid bacterium, Bacillus coagulans strain 36D1. Standards in Genomic Sciences. 5(3): 331-340.
220. Turner PC, Yomano LP, Jarboe LR, York SW, Baggett CL, Moritz BE, Zentz EB, Shanmugam KT, Ingram LO. 2012. Optical mapping and sequencing of the Escherichia coli KO11 genome reveal extensive chromosomal rearrangements, and multiple tandem copies of the Zymomonas mobilis pdc and adhB genes. J Ind Microbiol Biotechnol. 39(4):629-39
219. Wang Q, Ingram LO, Shanmugam KT. 2011. Evolution of D-lactate dehydrogenase activity from glycerol dehydrogenase and its utility for D-lactate production from lignocellulose. Proc Natl Acad Sci U S A. 108(47):18920-5.
218. Edwards, M., E.D. Henriksen, L.Yomano, B. Gardner, L.Sharma, L.O. Ingram, and J.Doran-Peterson. 2011. Addition of genes for cellobiase and pectinolytic activity in Escherichia coli for fuel ethanol production from pectin-rich lignocellulosic biomass. Appl & Environ Microbiol. 77(15): 5184-5191.
217. Wang, X., E.N. Miller, L.P. Yomano, X. Zhang, K.T. Shanmugam, and L.O. Ingram. Increased furfural tolerance due to oxidoreductase FucO in Escherichia coli for production of ethanol and lactate Appl. Environ. Microbiol. 77(15): 5132-5140.
216. Geddes, C.C., I. Nieves, and L.O. Ingram. 2011. Advances in ethanol production. Current Opinion in Biotechnology 22(3): 312-319. http://www.sciencedirect.com/science/article/pii/S0958166911000759
215. Nieves, I., C.C. Geddes, M. Mullinix, R.W. Hoffman, Z. Tong, E. Castro, K.T. Shanmugam, and L.O. Ingram. 2011.Injection of air into the headspace improves fermentation of phosphoric acid pretreated sugarcane bagasse by Escherichia coli MM170. Bioresource Technology.102:6959-6965. http://www.sciencedirect.com/science/article/pii/S096085241100530X
214. Nieves, I.U, C.C. Geddes, E.N. Miller, M.T. Mullinnix, R.W. Hoffman, Z. Fu, Z. Tong, and L.O. Ingram. 2011. Effect of reduced sulfur compounds on the fermentation of phosphoric acid pretreated sugarcane bagasse by ethanologenic Escherichia coli. Bioresour Technol. 2011 Apr; 102(8):5145-52. Epub 2011 Feb 24 http://www.sciencedirect.com/science/article/pii/S0960852411001933
208.
Geddes, C.C., M.T. Mullinix, I.U. Nieves, J.J. Peterson, R.W. Hoffman, S.W. York, L.P. Yomano, E.N. Miller, K.T. Shanmugam, L.O. Ingram 2010. Simplified process for ethanol production from sugarcane bagasse using hydrolysate-resistant Escherichia coli strain MM160.Bioresource Technology.102:2702-2711.
Appl. Environ Microbiol. 76(7): 2107-2114.
Appl Environ Microbiol. 76(7): 2107-2114
Appl. Environ Microbiology 75(19): 6132-6141.
Biotechnol Lett. 31:1389-1398.
Appl. Biochem. Biotechnol. 153:21-33.
Appl. Biochem Biotechnol. 7pp.
190. Peterson J.D., and L.O.Ingram. 2008. Anaerobic respiration in engineered Escherichia coli with an internal electron acceptor to produce fuel ethanol. Ann. N.Y. Acad. Sci. 1125: 363-372.
Biotechnol and Bioengineering. 99(5): 1140-1153.
188. Shanmugan, K.T. and L.O. Ingram. 2008. Engineering biocatalysts for production of commodity chemicals. Journal of Molecular Microbiology and Biotechnology. 15:8-15.
