Ben Dunn

1. B.M. Dunn, ed. Proteinases as Drug Targets, Royal Society of Chemistry, 2011, 271+ pages.

2. B. M. Dunn (2011) “The Aspartic Proteinases from the Malaria Parasite: Structure and Function of the Plasmepsins in: Proteinases as Drug Targets, (ed. B. Dunn), Royal Society of Chemistry.

3. Linda Janka, Jose Clemente, N. Vaiana, A. Sparatore, Sergio Romeo, and Ben M. Dunn 2008, Targeting the plasmepsin 4 orthologs of Plasmodium sp. With    “Double-Drug” inhibitors, Protein and Peptide Letters, 15, 868-873.

4.  Arthur H. Robbins, Ben M. Dunn, Mavis Agbandje-McKenna, and Robert McKenna 2008, Crystallographic evidence for non-coplanar catalytic aspartic acids in an aspartic protease resides in the Protein Data Bank. Acta Crystallographica, D65, 294-296.

5. Peng Liu, Melissa R. Marzahn, Arthur H. Robbins, Hugo Gutiérrez-de-Terán^?, David Rodríguez^?, Scott McClung, Stanley M. Stevens, Jr., Charles A. Yowell, John B. Dame, Robert McKenna, and Ben M. Dunn, 2009, Recombinant plasmepsin 1 from the human malaria parasite Plasmodium falciparum: Expression of an engineered variant, enzymatic characterization, combinatorial chemistry-based peptide inhibitor design and crystallographic analysis, and modeling of active site interactions of three plasmepsins, BIOCHEMISTRY, 48 (19), 4086-4099.

6. Kristina M. Orrling, Melissa R. Marzahn, Hugo Gutierrez-de-Teran, Johan Aqvist, Ben M. Dunn, Mars Lahred. 2009. Alpha-substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases. Bioorganic & Medicinal Chemistry, 17, pp 5933-5949.

7. Sarah K. Ho, Elena E. Perez, Stephanie L. Rose, Roxana M. Coman, Amanda C. Lowe, Wei Hou, Changxing Ma, Robert M. Lawrence, Ben M. Dunn, John W. Sleasman and Maureen M. Goodenow, 2009, Genetic determinants in HIV-1 Gag and Env V3 are related to viral response to combination antiretroviral therapy with a protease inhibitor. AIDS, 23, pp 1631-1640.

8. Jamie L. Kear, Mandy E. Blackburn, Angelo M. Veloro, Ben M. Dunn, and Gail E. Fanucci, (2009) “Subtype Polymorphisms Among HIV-1 Protease Variants Confer Altered Flap Conformations and Flexibility” J. Amer. Chem. Soc., 197, 14650-1.

9. Arthur H. Robbins, Roxana M. Coman, Mi Li, Marty Fernandez, Taylor Gilliland, Edith Bracho-Sanchez, Mavis Agbandje-McKenna, Alexander Wlodawer, Ben M. Dunn, and Robert McKenna (2010) “Crystal Structure of the Unbound Form of HIV-1 Subtype A Protease: A Comparative Study”, Acta Crystallographica Section D Biological Crystallography, 66,  233-242.

10. Aziza Akaddar; Cecile Doderer-Lang; Melissa Marzahn; Francois Delalande; Marc Mousli; Karen Helle; Alain Van Dorsselaer; Dominique Aunis; Ben M. Dunn; Marie-Helene Metz-Boutigue, Ermanno Candolfi  year “Catestatin, an endogenous Chromogranin A-derived peptide, inhibits in vitro growth of Plasmodium falciparum”, Cellular and Molecular Life, 67, 1005-1015.  

11. Ahu Demir, Raphael M. Oguariri, Andrew T. Magis, David A. Ostrov, Tomozumi Imamichi, Ben M. Dunn 2012 “Kinetic Characterization of Newly Discovered Inhibitors of Various Constructs of Human T-cell Leukemia Virus-1 Protease and their Effect on HTLV-1 Infected Cells”, Antiviral Therapy, accepted, Nov. 8, 2011, in press.

12. Mi Li, Alla Gustchina, Krisztina Matuz, Jozsef Tozser, Sirilak Namwong, Nathan E. Goldfarb, Ben M. Dunn and Alexander Wlodawer 2011 “Structural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus-related virus protease”, F.E.B.S. Letts., 278 (22), 4413-4424.

13. Jeffrey D. Carter, Adam N. Smith, Estrella G. Gonzales, Ian M. DeVera, Peter W. D’Amore, Maureen Goodenow, Ben M. Dunn, and Gail E. Fanucci (2012) “Single Point Drug-Selected Mutations Confer Marked Alterations in the Conformational Ensemble of HIV-1 Protease”,submitted to JACS.