Ph.D., Immunology

Osmania University, Hyderabad, INDIA ▪ 1993
M.S., Zoology

Osmania University, Hyderabad, INDIA ▪ 1986
M.S., State Merit Award.

Government of Andhra Pradesh, India. ▪ 1986
B.S., Biology, Applied Nutrition & Public Health

Osmania University, Hyderabad, INDIA ▪ 1984

Awards & Honors

Mid Career Outstanding Researcher Award.

University of Florida College of Medicine, Gainesville, FL. ▪ 2013
Excellence in Research Award

University of Florida College of Medicine, Gainesville, FL. ▪ 2009
Young Trainee Investigator Award.

American Federation of Clinical Research/Central Society for Clinical Research. USA. ▪ 1997
CSIR Young Investigator Travel Award.

Department of Biotechnology and Council of Scientific and Industrial Research, Government of India. ▪ 1995
CSIR-Post Doctoral Fellowship

Council of Scientific and Industrial Research, Government of India. ▪ 1994
Fogarty International Travel Award.

National Institutes of Health, Bethesda, USA. ▪ 1992
UGC-NET Senior Research Fellowship

University Grant Commission, Government of India. ▪ 1989
UGC-NET Junior Research Fellowship

University Grants Commission, India. ▪ 1986
State Merit Award

Government of Andhra Pradesh, India. ▪ 1986

Publications

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More Publications

Kamal A. Mohammed, N. Nasreen, M.J. Ward, and V.B. Antony. Macrophage Inflammatory Protein-1a: A C-C Chemokine in Parapneumonic Pleural Effusions. J. Lab. Clin. Med. 132(3): 202-209.1998.
Kamal A. Mohammed, N. Nasreen, M.J. Ward, Panadero F.R. and V.B. Antony. Mycobacterium Mediated Chemokine Expression in Pleural Mesothelial Cells: Role of C-C Chemokines in Tuberculous Pleurisy. J. Infec. Dis. 178: 1450-1456, 1998.
Nasreen N., Hartman D.L., Mohammed K.A., Antony V.B. Talc Induces Pleural Mesothelial cell Expression of Proinflammatory Cytokines and Intercellular Adhesion Molecule-1 (ICAM-1). Am. J. Respir. Crit. Care Med. 158: 971-978, 1998.
Kamal A. Mohammed, Nasreen N., Ward M.J., and Antony V.B. Helper T-cell type 1 and 2 Cytokines Regulate C-C Chemokine Expression in Mesothelial Cells. Am. J. Respir. Crit. Care Med. 159: 1653-1659, 1999.
Nasreen N., Mohammed K.A., Ward M.J., and Antony V.B. Mycobacterium-induced transmesothelial migration of monocytes into pleural space: role of intercellular adhesion molecule-1 in tuberculous pleurisy. J. Infec. Dis. 180(5):1616-1623, 1999.
Galffy G., Mohammed K.A., Nasreen N., Ward M.J., Antony V.B. Inhibition of interleukin-8 Reduces Malignant Pleural Mesothelioma Propagation in Nude Mouse Model. Interntl. J. Oncol. Res. 11(4):187-194, 1999.
Galffy G., Mohammed K.A., Ward M.J., Dowling P.A., Nasreen N., Antony V.B. Interleukin-8, an Autocrine Growth Factor for Malignant Mesothelioma. Cancer Research. 59: 367-371.1999.
Nasreen N., Mohammed K.A., Dowling P.A.,Ward M.J and Antony V.B. Talc Induces Apoptosis in Human Malignant Mesothelioma in vitro. Am. J. Respir. Crit. Care Med. 161(2 Pt 1):595-600, 2000.
Kamal A. Mohammed, Nasreen N., Ward M.J. and Antony V.B. Induction of Acute Pleural Inflammation by Staphylococcus aureus: I. CD4+ T cells Play a Critical Role in Experimental Empyema. J. Infec. Dis. 181(5):1693-1699, 2000.
Nasreen N., Mohammed K.A., Ward M.J. and Antony V.B. MCP-1 in pleural injury: CCR2 mediates haptotaxis of pleural mesothelial cells. Am J Physiol - Lung Cellu Mol Physiol. 278(3):L591-L598, 2000.
Kamal A. Mohammed, Nasreen N, Joyce Hardwick, Carolyn S. Logie, Carolyn E. Patterson, And Veena B. Antony. Bacterial Induction of Pleural Mesothelial Monolayer Barrier Dysfunction. Am J Physiol - Lung Cell Mol Physiol. 281:L119-L125, 2001.
Najmunnisa Nasreen, Mohammed K.A., Joyce Hardwick, Robert D. Van Horn, Kerry L. Sanders, Doerschuk C.M, Jeff W. Hott, and Veena B. Antony. Polar Production of IL-8 By Mesothelial Cells Promotes The Transmesothelial Migration of Neutrophils: Role of ICAM-1. J. Infec. Dis. 183(11):1638-1645, 2001.
Farzad Loghmani, Mohammed K.A., Najmunnisa Nasreen, Robert D. Van Horn, Joyce A. Hardwick, Kerry L. Sanders, and Veena B. Antony. Cytokines Mediate C-C (Monocyte Chemotactic Peptide) and C-X-C (Interleukin 8) Chemokine Expression in Human Pleural Fibroblasts. Inflammation, 26(2):73-82, 2002.
Matthew C. Lundien, Mohammed K.A., Najmunnisa Nasreen, R.S. Tepper, Joyce A. Hardwick, Kerry L. Sanders, Robert D. Van Horn and Veena B. Antony. Induction of MCP-1 Expression in Airway Epithelial Cells : Role of CCR2 Receptor in Airway Epithelial Injury. J. Clin. Immunol. 22(3):144-152, 2002.
Ajay B. Antony, Robert S. Tepper, Mohammed K.A., Cockroach Extract Allergen Induces Permeability Change in Human Bronchial Airway Epithelial Cells. J. Allergy Clin Immunol. 110(4):589-595, 2002.
Nasreen Najmunnisa, Mohammed K.A., Kerry L. Sanders, Joyce Hardwick, Robert D. Van Horn, And Veena B. Antony.Staphylococcus aureus Stimulated Pleural Mesothelial Cells (PMC) Modulate Polymorphnuclear Leukocyte (PMN) Apoptosis. J. Clin Immunol. 23(1):1-10, 2003.
Najmunnisa Nasreen, Mohammed K.A., Joyce Hardwick, Robert D. Van Horn, Kerry L. Sanders, Hasmeena Kathuria, Farzad Loghmani, and Veena B. Antony. Low molecular weight hyaluronan induces malignant mesothelioma cell (MMC) proliferation and haptotaxis: Role of CD44 receptor in MMC proliferation and haptotaxis. Oncology Research. 13(2):71-78, 2002.
Shriram P.S., Mohammed K.A., Najmunnisa Nasreen, Joyce Hardwick, Robert D. Van Horn, Kerry L. Sanders, Farzad Loghmani, Matthew Lundien and Veena B. Antony. Metastatic Ovarian Cancer Increases Pleural Permeability. Oncology Research. 13(2):79-85, 2002.
Kamal A. Mohammed, Najmunnisa Nasreen, Joyce Hardwick, Robert D. Van Horn, Kerry L. Sanders, And Veena B. Antony. Mycobacteria Induces Pleural Mesothelial Permeability by down-regulating beta-catenin Expression. Lung,181(2):57-66, 2003.
Ramit K. Sharma, Mohammed K.A., Najmunnisa. Nasreen, J. Hardwick, BA; R. D. Vn Horn, BS; Carlos Ramirez-Icaza, and V. B. Antony. Defensive role of Pleural Mesothelial Cell (PMC) Sialomucins in Tumor Metastasis. Chest, 124(2) 682-687, 2003.
Gail Ramirez-Icaza, Mohammed K.A., Nasreen N., Joyce Hardwick J.A., Van Horn R.D., Sanders K. L., J. Tian, Johnson M. T. and Antony V. B. Th2 Cytokines IL-4 and IL-13 Down Regulate Paxillin Expression in Bronchial Airway Epithelial Cells. J Clin Immunol., 24(4):426-434, 2004.
Kilani Muna M., Mohammed K.A., Nasreen N., Hardwick J.A., Tepper R. S. and Antony V. B. Respiratory Syncytial Virus Causes Increased Bronchial Epithelial Permeability. Chest. 126(1):186-191; 2004.
Antony V.B., Nasreen N., Mohammed K.A., Sriram P.S., Frank W., Schonfeld N., and Lodenkemper R. Talc Pleurodesis: Pleural fluid bFGF mediates pleural fibrosis. Chest. 126(5):1522-528, 2004.
Kilani MM, Mohammed KA, Nasreen N, Tepper RS, Antony VB. RSV causes HIF-1alpha stabilization via NO release in primary bronchial epithelial cells. Inflammation. 28(5):245-251, 2004.
Nasreen N., Mohammed K.A., Kerry L. Sanders, Joyce Hardwick, Robert D. Van Horn, Jun tain, Ramit K. Sharma, Carlos Ramirez-Icaza, Muna M. Kilani, Chade Hage and Veena B. Antony. Pleural Mesothelial cell (PMC) defense mechanisms against malignancy. Oncol. Res. An Internatl. J. 14(3):155-161, 2004.
Antony V.B., Nasreen N., Mohammed K.A., Sriram P.S., Frank W., Schonfeld N., and Lodenkemper R. Talc Pleurodesis: Pleural fluid bFGF mediates pleural fibrosis. Chest. 126(5):1522-1528; 2004.
Nasreen N, Mohammed KA, Antony VB. Silencing the receptor EphA2 suppresses the growth and haptotaxis of malignant mesothelioma cells. Cancer. 15;107(10):2425-2435, 2006.
Nasreen Najmunnisa, Mohammed, K.A., Brown, S., Su,Y.,Sriram, P.S., Moudgil, B., Loddenkemper, R., and Antony, V.B. Tal mediates angiostasis in malignant pleural effusions via endostatin induction in Pleural Mesothelial Eur Respir J. Apr;29(4): 761-769, 2007.
Najmunnisa Nasreen, Mohammed, K.A., Hussain, T., Lai Y and Antony, VB. Receptor EphA2 activation with EphrinA1 Suppresses Growth of Malignant Mesothelioma. Cancer Letters. 18;258(2):215-222, 2007.
Mohammed K.A., Nasreen N, and Antony V. B. Staphylococcus aureus Induces Differential Expression of C-fos, C-junand Mediates Apoptosis in Pleural Mesothelial Cells. Lung. 185(6):355-365, 2007 (Corresponding author: Kamal A Mohammed).
Kamal A. Mohammed, Nasreen N, Robert S. Tepper, and Veena B. Antony. Inhibition of P44/42 MAPK Ameliorates Cyclical Stretch induced PlGF release in Bronchial Airway Epithelial Cells. Am J Physiol Lung Cell Mol Physiol.292(2):L559-L566, 2007 (Corresponding author: Kamal A Mohammed).
Brown, S. C., Mohammed, K.A., Sharma, P., Nasreen, N., V.B Antony, and B.M. Moudgil, "Influence of Shape, Adhesion and Simulated Lung Mechanics on Amorphous Silica Nanoparticle Toxicity.Advanced Powder Technology, 18(1), 69-79, 2007.
Yi-Mu Lai, Mohammed, K.A., Nasreen, n., Baumuratov, A., Bellew, B.F., and Veena B. Antony. Induction of cell cycle arrest and apoptosis by BCG infection in cultured human bronchial airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 293(2):L393-L401, 2007.
Tajamul Hussain, Nasreen, N., Lai, Y., Bellew, B. F., Antony, V. B., Mohammed, K.A. Innate Immune Responses in Murine Pleural Mesothelial Cells: TLR2 Dependent Induction of b-defensin-2 by Staphylococcal Peptidoglycan^.Am J Physiol Cell and Mol Physiol., Sep; 295(3):L461-L470, 2008.
Najmunnisa Nasreen*, Mohammed K. A.*, Mubarak K.K., Baz M.A., Akindipe O.A., Fernandez-Bussy S., and Antony V.B. Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-b1 in vitro. Am J Physiol Cell and Mol Physiol. 2009 Jul; 297(1):L115-24. Epub 2009 May 1. *Equal contribution.
Weihong Han, Wei Wang, Mohammed, K.A., Yunchao Su.α-Defensins increase lung fibroblast proliferation and collagen synthesis via Wnt/β-Catenin pathway. EMBO J. 2009 Nov; 276(22):6603-14.
Montes-Worboys A., Brown S., Regev D., Bellew B.F., Mohammed K.A., Faruqi I., Sharma P., Moudgil B.,Antony V.B. Targeted delivery of amikacin into granuloma. Am J Respir Crit Care Med. 2010 Dec 15;182(12):1546-53. Epub 2010 Aug 6.
Mohammed, K.A., Xiaohong Wang, Antony, VB, and Nasreen N. Silencing receptor EphA2 Induces Apoptosis and attenuate tumor growth in Malignant Mesothelioma. Am J Cancer Research, 2011; 1(3): 419-431. Epub 2011 Feb 10.
Hung-Yen Lee, Mohammed K. A., Goldberg E.P. and N. Nasreen.Targeted lung cancer therapy using ephrinA1-loaded albumin microspheres. J Pharm Pharmacol. 2011 Nov; 63(11):1401-10.
Nazli Khodayari, Mohammed K.A., Eugene P. Goldberg, Veena B. Antony, and N. Nasreen. EphrinA1Inhibits Malignant Mesothelioma tumor growth via let-7 microRNA mediated repression of the RAS oncogene. Cancer Gene Therapy. 2011 Nov; 18(11):806-16. doi: 10.1038/cgt.2011.50. Epub 2011 Aug 26.
Nasreen, N, Khodayari N., Bhagyalaxmi Sukka-Ganesh, Peruvemba S., and Kamal A. Mohammed. Fluticasone Propionate and Salmeterol Combination Induces SOCS-3 Expression in Airway Epithelial Cells. International Journal of Immuno-pharmacology, 2012 Jan;12(1):217-25. doi: 10.1016/j.intimp.2011.11.014.
Mubarak K.K., Worboys A.M., Regev D., Nasreen N., Mohammed K.A., Faruqi I., Hensel E., Baz M.A., Akindipe O.A., Bussy S.F., Nathan S.D., and Antony V.B. Parenchymal trafficking of pleural mesothelial cells in idiopathic pulmonary fibrosis: Potential role in pathogenesis. Eur Respir J. 2012 Jan; 39(1):133-40. Epub 2011 Jul 7.
Nasreen N., Khodayari N., and Mohammed K.A. Advances in Malignant Pleural Mesothelioma therapy: Targeting EphA2 a Novel Approach.Am J Cancer Research Am J Cancer Res 2012; 2(2):222-234.
Sukka-Ganesh B, Mohammed KA, Kaye F, Goldberg EP, Nasreen N. Ephrin-A1 Inhibits NSCLC Tumor Growth via Induction of Cdx-2 a Tumor Suppressor GeneBMC Cancer. 2012 Jul 23;12(1):309. [Epub ahead of print].
Hung-Yen Lee, Mohammed KA., Goldberg EP., and Nasreen N. Arginine – conjugated Albumin Microspheres inhibits Proliferation and Migration in Lung Cancer Cells. Am J Cancer Research; 2013; 3(3): ISSN:2156-6976/ajcr_ms0000195[Epub ahead of print].
Hung-Yen Lee, Mohammed K.A., Sharma P, Moudgil BM., William CL, and Nasreen N. Targeted delivery of let-7a microRNA encapsulated ephrin-A1 conjugated liposomal nanoparticles inhibit tumor growth in lung cancer. International Journal of Nano-medicine. 2013;8:4481-94. doi: 10.2147/IJN.S41782. Epub 2013 Nov 21.
Lee HY, Mohammed KA, Kaye F, Sharma P, Moudgil BM, Clapp WL, Nasreen N. Targeted Delivery of Let-7a MicroRNA Encapsulated-EphrinA1 Conjugated Liposomal Nanoparticles Inhibit Tumor Growth in Lung Cancer.Intl. Journal of Nano medicine, 2013; 8:4481-94.
Nasreen N, Gonzalves L, Sriram PS, Mohammed KA. Fluticasone furoate is more effective than mometasone furoate in restoring tobacco smoke inhibited SOCS-3 expression in airway epithelial cells. Int. Immunopharmacol. 2014 Mar; 19(1):153-60.doi10.1016/j.intimp.2013.12.029. Epub 2014 Jan 13.
Nasreen N, Khodayari N, Sriram PS, Patel J, Mohammed KA. Tobacco Smoke induces Epithelial Barrier Dysfunction via Receptor EphA2 Signaling. Am J Physiol Cell Physiol. 2014 Apr 9. [Epub ahead of print].
Yuan Z, Mehta HJ, Mohammed KA, Nasreen N, Roman R, Brantly M, Sadikot RT. TREM-1 Is Induced in Tumor Associated Macrophages by Cyclo-Oxygenase Pathway in Human Non-Small Cell Lung Cancer. PLoS One. 2014 May 19;9(5); eCollection 2014.Y
Yue Jin, Anitha K. Shenoy, Veerle Rottiers, Hao Chen,Huacheng Luo, Huangxuan Shen, Tong Lin, Ryan Fiske, Ting Chen, Lizi Wu, Kamal A. Mohammed, Siu Sylvia Lee, Jianrong Lu FBXO11 regulates epithelial integrity and homeostasis by targeting Snail transcription factors for degradation. Cell Reports, 2014 (In review).

Other Professional Activities

Invited reviewer on peer reviewed journals: 1. Journal of Immunology 2. American Journal of Physiology: Lung Cell & Molecular Physiology 3. Journal of Infectious Disease 4. Lung 5. Archivum Immunologiae et Therapiae Experimentalis (Polish immunological journal published in English) 6. International Journal of Immunopharmacology 7. Experimental Cell Research 8. Journal of Allergy and Therapy Membership in Scientific Societies: 1. Member of American Federation for Medical Research. 2. Member of American Thoracic Society. 3. Member of American Society for Pharmacology and Experimental Therapeutics. 4. Member of Indiana Thoracic Society, The Medical Section of the American Lung Association of Indiana.