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Todd Brusko
Professor
MD-PATHOLOGY-GENERAL | COLLEGE-MEDICINE
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Title
03-2025
Role of ADAM17 in MDSC-Mediated Development of Pulmonary
Role of ADAM17 in MDSC-Mediated Development of Pulmonary
03-2025
The Role and Mechanisms of Lipid and Lipoprotein Dysregu
The Role and Mechanisms of Lipid and Lipoprotein Dysregu
09-2023
The Network for Pancreatic Organ donors with Diabetes (nPOD) : A Collaborative Type 1 Diabetes Research Project
The Network for Pancreatic Organ donors with Diabetes (nPOD) : A Collaborative Type 1 Diabetes Research Project
09-2023
Collaborative Type 1 Diabetes Research Project: The Network for Pancreatic Organ donors with Diabetes (nPOD)
Collaborative Type 1 Diabetes Research Project: The Network for Pancreatic Organ donors with Diabetes (nPOD)
07-2023
Immunocore ImmTAAI technology and its potential use to treat type 1 diabetes autoimmunity
Immunocore ImmTAAI technology and its potential use to treat type 1 diabetes autoimmunity
06-2023
A 3D Tissue Map of the Human Lymphatic System
A 3D Tissue Map of the Human Lymphatic System
05-2023
Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapy
Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapy
05-2023
Immune Function and the Progression to Type 1 Diabetes
Immune Function and the Progression to Type 1 Diabetes
05-2023
Multi-modal single cell analysis for investigation of T1D pathogenesis
Multi-modal single cell analysis for investigation of T1D pathogenesis
04-2023
Impact of T1D Risk Alleles on Pancreatic Islet Gene Expression in TIGER and PANC-DB Studies
Impact of T1D Risk Alleles on Pancreatic Islet Gene Expression in TIGER and PANC-DB Studies
04-2023
Regulatory T-cells Engineering and Functionality Validation
Regulatory T-cells Engineering and Functionality Validation
03-2023
CD226 inhibition to prevent regulatory T cell dysfunction in type 1 diabetes
CD226 inhibition to prevent regulatory T cell dysfunction in type 1 diabetes
01-2023
Human Atlas of Neonatal Developmental and Early Life Pancreas / Immunity (HANDEL)-P/I Continuation
Human Atlas of Neonatal Developmental and Early Life Pancreas / Immunity (HANDEL)-P/I Continuation
09-2022
T cell receptor sequencing in type 1 diabetes - biomarker discovery and technology development
T cell receptor sequencing in type 1 diabetes - biomarker discovery and technology development
06-2022
Human Islet Research Enhancement Center for the Human Islet Research Network: "The SIRP:CD47 Signaling Pathway in Pancreatic ?-Cell Survival"
Human Islet Research Enhancement Center for the Human Islet Research Network: "The SIRP:CD47 Signaling Pathway in Pancreatic ?-Cell Survival"
05-2022
Characterization of SLE-susceptibility loci on mouse chromosome 1
Characterization of SLE-susceptibility loci on mouse chromosome 1
12-2021
Human Atlas of Neonatal Development and Early-Life Immunity (HANDEL-I)
Human Atlas of Neonatal Development and Early-Life Immunity (HANDEL-I)
12-2021
An Imputation-Consistency Algorithm for Biomedical Complex Data Analysis
An Imputation-Consistency Algorithm for Biomedical Complex Data Analysis
08-2021
Engineered Tregs to block autoantibody development and progression of type 1 diabetes
Engineered Tregs to block autoantibody development and progression of type 1 diabetes
07-2021
Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions
Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions
06-2021
TrialNet Clinical Center infrastructure support
TrialNet Clinical Center infrastructure support
03-2021
Advanced Liver 3-D Tissue Models for Drug Development Applications to Support Toxicology, Drug Metabolism, Target ID & Pharmacology
Advanced Liver 3-D Tissue Models for Drug Development Applications to Support Toxicology, Drug Metabolism, Target ID & Pharmacology
02-2021
The CD226 amd TIGIT costimulatory Axis in Type 1
The CD226 amd TIGIT costimulatory Axis in Type 1
09-2020
Amendment 2 - Genetic Data Analysis
Amendment 2 - Genetic Data Analysis
08-2020
Single cell sequencing for islet-reactive T cell clonotype and transcript signatures
Single cell sequencing for islet-reactive T cell clonotype and transcript signatures
05-2020
Delivery of biomaterial-conjugated regulatory T Cells for the amelioration of Type 1 Diabetes
Delivery of biomaterial-conjugated regulatory T Cells for the amelioration of Type 1 Diabetes
11-2019
Clinical Trial Planning Grant for Treg Therapy in Type I Diabetes
Clinical Trial Planning Grant for Treg Therapy in Type I Diabetes
07-2019
Safety & Efficacy of Imatinib for Preserving Beta-cell Function in New-Onset T1D
Safety & Efficacy of Imatinib for Preserving Beta-cell Function in New-Onset T1D
07-2019
Insulin Specific T and B cells in Type 1 Diabetes
Insulin Specific T and B cells in Type 1 Diabetes
06-2019
The impacts of co-stimulatory molecules CD226 and TIGIT on T1D development
The impacts of co-stimulatory molecules CD226 and TIGIT on T1D development
06-2019
Functional Interrogation of Non-Coding Type 1 Diabetes Risk Variants in Human Immune Cells and Beta Cells
Functional Interrogation of Non-Coding Type 1 Diabetes Risk Variants in Human Immune Cells and Beta Cells
06-2019
Genetic Regulation of Human Beta Cell Destruction
Genetic Regulation of Human Beta Cell Destruction
06-2019
Characterization of T cell Autoreactivity in Type 1 Diabetes
Characterization of T cell Autoreactivity in Type 1 Diabetes
05-2019
Disruption of T cell tolerance in type 1 diabetes: Specificity and repertoire of Tregs in T1D
Disruption of T cell tolerance in type 1 diabetes: Specificity and repertoire of Tregs in T1D
03-2019
Biomaterial-based delivery of Interleukin-2 to Regulatory T Cells for the amelioration of Type 1 diabetes
Biomaterial-based delivery of Interleukin-2 to Regulatory T Cells for the amelioration of Type 1 diabetes
12-2018
ELUCIDATING THE IMMUNOREGULATORY ROLES OF TIGIT AND CD226DURING T1D
ELUCIDATING THE IMMUNOREGULATORY ROLES OF TIGIT AND CD226DURING T1D
07-2018
Low-Dose IL-2 in Established T1D
Low-Dose IL-2 in Established T1D
06-2018
Islet-reactive TCR clones in humanized mice generated with type 1 diabetes patient
Islet-reactive TCR clones in humanized mice generated with type 1 diabetes patient
06-2018
Characterization of SLE-susceptibility loci on mouse chromosome 1
Characterization of SLE-susceptibility loci on mouse chromosome 1
06-2018
Immune Function and the Progression to Type 1 Diabetes
Immune Function and the Progression to Type 1 Diabetes
04-2018
T cell therapy against factor VIII inhibitors
T cell therapy against factor VIII inhibitors
04-2018
Altered Immunometabolic Associations With Type 1 Diabetes Clinical Status and Genetic Risk.
Altered Immunometabolic Associations With Type 1 Diabetes Clinical Status and Genetic Risk.
12-2017
Impacts of co-stimulation molecules CD226 and TIGIT on NK cell immunoregulation and function during Type 1 diabetes
Impacts of co-stimulation molecules CD226 and TIGIT on NK cell immunoregulation and function during Type 1 diabetes
12-2017
The George S. Eisenbarth nPOD Award for Team Science
The George S. Eisenbarth nPOD Award for Team Science
04-2017
Investigating Human Autoreactive T Cell Responses in Humanized Mice
Investigating Human Autoreactive T Cell Responses in Humanized Mice
01-2017
Characterization and in silico reconstruction of TCRs for modeling autoreactive T cells in T1D
Characterization and in silico reconstruction of TCRs for modeling autoreactive T cells in T1D
12-2016
Determine the influence of IL-12 and IL-18 signaling on Treg activity
Determine the influence of IL-12 and IL-18 signaling on Treg activity
07-2016
Cord Blood Expansion of Regulatory T cells
Cord Blood Expansion of Regulatory T cells
06-2016
Minimizing Leukemia Relapse: A Phase I, Dose Escalation Study of Decitabine in High Risk Pediatric and Young Adult Leukemia Post Allogeneic Stem Cell Transplantation
Minimizing Leukemia Relapse: A Phase I, Dose Escalation Study of Decitabine in High Risk Pediatric and Young Adult Leukemia Post Allogeneic Stem Cell Transplantation
06-2016
Influence of IL-12 and IL-18 on immunoregulation and type 1 diabetes pathogenesis
Influence of IL-12 and IL-18 on immunoregulation and type 1 diabetes pathogenesis
02-2016
A novel biomaterial-based therapy to prevent type 1 diab
A novel biomaterial-based therapy to prevent type 1 diab
12-2015
Nanoparticle-coupled Tregs for the Treatment of Type 1 D
Nanoparticle-coupled Tregs for the Treatment of Type 1 D
05-2015
Regulatory T Cells with Chimeric Antigen Receptor for Im
Regulatory T Cells with Chimeric Antigen Receptor for Im
12-2014
Cord Blood (UCB) T Cell (Treg)
Cord Blood (UCB) T Cell (Treg)
12-2014
Lymphocyte mitochondrial dysfunction in type 1 diabetes
Lymphocyte mitochondrial dysfunction in type 1 diabetes
09-2012
Post-transcriptional regulation of pancreas-targeting nT
Post-transcriptional regulation of pancreas-targeting nT
08-2012
Nanoparticle-coupled Tregs for the treatment of type 1 d
Nanoparticle-coupled Tregs for the treatment of type 1 d
02-2012
Investigating human autoreactive T cell responses in
Investigating human autoreactive T cell responses in
09-2011
Development of antigen-specific human Tregs for the trea
Development of antigen-specific human Tregs for the trea
Publications
Search Google Scholar for Todd Brusko
Co-Investigator Network
Thomas Angelini
University of Florida
EG-MECHANICAL / AEROSPACE ENG, College-Engineering
t.e.angelini@ufl.edu
Mark Atkinson
Professor
University of Florida
MD-PATHOLOGY, College-Medicine
atkinson@ufl.edu
Rhonda Bacher
Assistant Professor
University of Florida
PHHP-COM BIOSTATISTICS, Phhp-Com Integrated Programs
rbacher@ufl.edu
Leandro Balzano Nogueira
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
leobalzano@ufl.edu
Moanaro Biswas
University of Florida
MD-PEDS-CELL / MOLEC THERP DIV, College-Medicine
narobiswas@ufl.edu
Maigan Brusko
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
maigan@ufl.edu
Andrew Bryant
University of Florida
MD-PULMONARY MEDICINE, College-Medicine
andrew.bryant@medicine.ufl.edu
Martha Campbell Thompson
Professor
University of Florida
MD-PATHOLOGY, College-Medicine
mct@ufl.edu
Paul Castillo Caro
Assistant Professor
University of Florida
MD-PEDS-HEMATOLOGY, College-Medicine
castillopa@ufl.edu
Jing Chen
Associate Scientist
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
jic24@pathology.ufl.edu
Seung-Chul Choi
Research Assistant Scientist
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
seungchulchoi@ufl.edu
Inactive Expert
Michael Clare-Salzler
Professor Emeritus
University of Florida
MD-SURGERY, College-Medicine
salzler@ufl.edu
Patrick Concannon
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
patcon@ufl.edu
Susmita Datta
Professor
University of Florida
PHHP-COM BIOSTATISTICS, Phhp-Com Integrated Programs
susmita.datta@ufl.edu
Jon Dobson
Professor
University of Florida
EG-BIOMEDICAL ENGINEERING, College-Engineering
jdobson@ufl.edu
Inactive Expert
Lamis Eldjerou
CLIN AST PROF
University of Florida
MD-CANCER CTR CLINICAL TRIALS, College-Medicine
leldjerou@peds.ufl.edu
Faheem Guirgis
Vice Chair of Research; Professor; Co-Director, CTSI KL2 Program
University of Florida
MD-EMERGENCY MED-AED, College-Medicine
fguirgis@ufl.edu
David Hahn
Courtesy Professor
University of Florida
EG-MECHANICAL / AEROSPACE ENG, College-Engineering
dwhahn@ufl.edu
Michael Haller
Professor and Chief
University of Florida
MD-PEDS-ENDOCRINOLOGY, College-Medicine
hallerms@ufl.edu
Roland Herzog
Associate Professor
University of Florida
MD-PEDS-CELL / MOLEC THERP DIV, College-Medicine
rherzog@ufl.edu
Laura Jacobsen
Assistant Professor
University of Florida
MD-PEDS-ENDOCRINOLOGY, College-Medicine
lauraj@ufl.edu
Benjamin Keselowsky
Professor
University of Florida
EG-BIOMEDICAL ENGINEERING, College-Engineering
bkeselowsky@bme.ufl.edu
Michael Kladde
Professor & Director of Center for Epigenetics
University of Florida
MD-BIOCHEM / MOLECULAR BIOL, College-Medicine
kladde@ufl.edu
Christiaan Leeuwenburgh
Professor Department of Physiology and Aging
University of Florida
MD-PHYSIOLOGY AND AGING, College-Medicine
cleeuwen@aging.ufl.edu
Faming Liang
University of Florida
PHHP-COM BIOSTATISTICS, Phhp-Com Integrated Programs
faliang@ufl.edu
Clayton Mathews
Sebastian Family Professor
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
cxm@ufl.edu
Peter McFetridge
Associate Professor
University of Florida
Biomedical Engineering, College Of Engineering / Biomedical Engineering
pmcfetridge@bme.ufl.edu
Lauren McIntyre
Professor
University of Florida
MD-MOLECULAR GENTCS / MICROBIO, College-Medicine
mcintyre@ufl.edu
Duane Mitchell
Director - UF Clinical and Translational Science Institute; Assistant Vice President for Research - University of Florida; Associate Dean - UF College of Medicine
University of Florida
MD-NEUROLOGICAL SURGERY, College-Medicine
duane.mitchell@neurosurgery.ufl.edu
Lyle Moldawer
Professor
University of Florida
MD-SURGERY-TRAUMA, College-Medicine
moldawer@surgery.ufl.edu
Laurence Morel
PROFESSOR
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
morel@pathology.ufl.edu
Harry Nick
PROFESSOR
University of Florida
MD-NEUROSCIENCE, College-Medicine
hnick@ufl.edu
Maxim Norkin
University of Florida
MD-HEMATOLOGY/ONCOLOGY, College-Medicine
norkinm@ufl.edu
Kevin Otto
Professor
University of Florida
EG-BIOMEDICAL ENGINEERING, College-Engineering
kevin.otto@bme.ufl.edu
Glyn Palmer
University of Florida
MD-ORTHOPAEDICS / REHAB, College-Medicine
palmegd@ortho.ufl.edu
Daniel Perry
Assistant Research Scientist
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
perryd@pathology.ufl.edu
Edward Phelps
University of Florida
EG-BIOMEDICAL ENGINEERING, College-Engineering
ephelps@bme.ufl.edu
Desmond Schatz
PROF & ASO CHR
University of Florida
MD-PEDS-ENDOCRINOLOGY, College-Medicine
schatda@peds.ufl.edu
Melanie Shapiro
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
mrshapir@ufl.edu
Robert Sharp
Cell Culture Biologist
University of Florida
MD-NEUROLOGY-MOVEMENT DISORDER, College-Medicine
rsharp07@ufl.edu
Elizabeth Shenkman
Professor and Chair
University of Florida
MD- Health Outcomes and Policy, College-Medicine
eas@ichp.ufl.edu
Eric Sobel
Associate Professor, Program Director
University of Florida
MD-RHEUMATOLOGY, College-Medicine
eric.sobel@medicine.ufl.edu
Cheryl Stabler Anderson
Professor
University of Florida
EG-BIOMEDICAL ENGINEERING, College-Engineering
cstabler@bme.ufl.edu
Brent Sumerlin
Professor
University of Florida
LS-CHEMISTRY-GENERAL, College-Liberal Arts/Sciences
sumerlin@ufl.edu
Naohiro Terada
Professor
University of Florida
VM-SACS, College-Veterinary Med
terada@pathology.ufl.edu
Mark Wallet
Assistant Professor
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
mawallet@pathology.ufl.edu
Shannon Wallet
Chair & Professor
University of Florida
DN-ORAL BIOLOGY, College-Dentistry
swallet@dental.ufl.edu
Clive Wasserfall
Asst in
University of Florida
MD-PATHOLOGY, College-Medicine
clive@ufl.edu
Wen I Yeh
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
wiyeh@ufl.edu
Lei Zhou
Professor
University of Florida
MD-MOLECULAR GENTCS / MICROBIO, College-Medicine
leizhou@ufl.edu
Websites
0000-0003-2878-9296
Search Google Scholar for Todd Brusko
Contact Information
tbrusko@ufl.edu
3522739255
PO Box 100275 GAINESVILLE, FL 32610
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