Research Terms
Biochemistry Molecular Biology Biomedicine Chemistry Science
Liu Y and Wilson S.H. DNA base excision repair: a mechanism of trinucleotide repeat expansion.
Trends Biochem Sci. 2012 Jan 27. [Epub ahead of print]
Naidu, M.D., Agarwal R., Pena, L. A., Cunha, L., Mezei, M., Shen M., Wilson III, D.M. Liu, Y.,
Sanchez, Z., Wilson, S.H. and Waring, M.J. (2011) Lucanthone and its derivative
Hycanthone inhibit Apurinic Endonuclease-1 (APE1) by direct protein binding PLoS
One 6 (9):e23679.
Prasad, R. Beard, W.A., Batra, V., Liu, Y. and Wilson, S.H. (2011) A Review of recent
experiments on step-to-step “hand-off” of the DNA intermediates in Mammalian Base
Excision Repair Pathways. Mol Biol (Mosk). 45(4):586-600.
Wilson, S.H., Beard, W.A., Shock, D. D., Batra, V.K., Cavanaugh, N. A., Prasad, R., Hou, E.
W., Liu, Y., Asagoshi, K., Horton, J.K., Stefanick, D. F., Kedar, P.S., Carrozza, M. J.,
Masaka, A., Heacock, M.L. (2010) Base Excision Repair and Design of Small Molecule
Inhibitors of Human Polymerase b. Cellular and Molecular Life Sciences 67:
3633-3647.
Khodyerva, S.N., Prasad, R., Ilina, E.S., Sukhanova, M.V.m Kutuzov, M.M., Liu, Y., Hou,
E.W., Wilson, S.H., Lavrik, O.I. (2010) Apurinic/apyrimidinic (AP) site recognition by
the 5'-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1). Proceedings of
National Academy of Science U S A 107(51): 22090-5.
Asagoshi, K., Liu, Y., Masaoka, A., Lan, L., Prasad, R., Horton, J.K., Brown, A.R., Wang, XH.,
Bdour, H.M., Sobol, R.W., Taylor, J., Yasui, A. and Wilson, S.H. (2010) DNA
Polymerase β –Dependent Long Patch Base Excision Repair of UV-Induced pyrimidine
Photoproducts in Nucleotide Excision Repair-Deficient Cells. DNA repair (Amst) 9
(2): 109-119.
Liu, Y., Prasad, R. Wilson, S.H. (2010) HMGB1: Roles in Base Excision Repair and Related
Function. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms-
2010 Jan-Feb Special Edition (ed. Michael Bustin), 1799 (1-2): 119-130.
Liu, Y., Prasad, R., Beard, W.A., Hou, E.W., Horton, J.K., McMurray, C.T. and Wilson, S.H.
(2009) Coordination Between Polymerase β and FEN1 Modulate CAG Repeat
Expansion. Journal of Biological Chemistry 284 (41): 28352-28366.
Prasad, R., Liu, Y., Deterding, L.J., Poltorasky, V.P., Kedar, P.S., Horton, J.K., Kanno, S.,
Asagoshi, K., Hou, E.W., Khodyreva, S.V., Lavrik, O.I., Tomer, K.B., Yasui, A. and
Wilson, S.H. (2007) HMGB1 Is a Cofactor in Mammalian Base Excision Repair.
Molecular Cell 27:829-841.
Kovtun, I.V., Liu, Y., Bjoras, M., Klungland, A., Wilson, S.H. and McMurray, C.T. (2007)
OGG1 Initiates Age-dependent CAG Trinucleotide Expansion in Somatic Cells. Nature,
447 (24):447-452.
Liu, Y., Prasad, R., Beard, W.A., Kedar, P.S., Hou, E.W., Shock, D.D. and Wilson, S.H. (2007)
Coordination of Steps in Single-nucleotide Base Excision Repair Mediated by
Apurinic/Apyrimidinic Endonuclease 1 and DNA Polymerase β. Journal of Biological
Chemistry 282 (18):13532-13541.
Liu, Y., Beard, W.A., Shock, D.D., Prasad, R., Hou, E.H. and Wilson, S.H. (2005) DNA
Polymerase β and Flap Endonuclease 1 Enzymatic Specificities Sustain DNA Synthesis
for Long-Patch Base Excision Repair. Journal of Biological Chemistry 280 (5):3665-
3674.
