Opportunity
The University of North Florida is seeking companies interested in commercializing new synthetic methods for the preparation of pentauorosulfanyl (SF5) aromatic diazonium salts and the application of such salts as building blocks for a wide variety of compounds useful in biomedical, pharmaceutical, agricultural, and materials applications. The new methods developed at the University of North Florida facilitate access to a wide variety of SF5-aromatic compounds whose synthesis by other means is challenging and not economical due to their reliance on exotic/hazardous reagents and harsh conditions.
Application
SF5-bearing molecules have important biological properties and are of current interest in a wide variety of fields. The development of synthetic methods in this invention enable facile access to novel SF5-aromatics and to a large assortment of SF5-bearing molecules for use in high-performance polymers, liquid crystals, pharmaceuticals, and pesticides, areas that are highly dependent on the availability of these small molecule building blocks for producing functional compounds
Invention Details
Compounds in the pentauorosulfanyl (SF5) group impart a number of favorable physical and chemical characteristics including thermal, hydrolytic, and chemical stability, high density, high electronegativity, and high lipophilicity. These favorable characteristics have prompted a high degree of interest in SF5-organics for practical applications in the biomedical, agricultural, and materials elds. This invention provides a versatile, readily available, and easily produced starting pentauorosulfanyl-substituted compound for use in pentauorosulfanyl-based synthesis. Specically, the invention allows for the synthesis and isolation of 4-(pentauorosulfanyl)benzenediazonium tetrauoroborate salt, which can be further deployed in a wide assortment of reactions to form novel SF5-bearing alkenes, alkynes, and biaryl derivatives, demonstrating the broad utility of pentauorosulfanyl diazonium salts as building blocks of SF5-aromatics.
Brochure
