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Antimony-resistant Bacteria Have Master Regulator

Barry Rosen has earned his fifth science journal cover—and his third since joining FIU. Rosen is a world-renowned expert in the detoxification and transport of metals in yeast, bacteria, mammals, protozoans, and plants. His most recent cover featured his study of bacteria that are resistant to antimony, a highly toxic metalloid..

“Chinese researchers isolated the bacteria from an antimony mine. We cloned the genes that allowed them to grow in the presence of antimony. And we found they had a master regulator, like an on/off light switch, that turns on in the presence of antimony to pump it out of the cell,” said Rosen.

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