Research selected as one of the Highlights of National Science Foundation funded research

National Science Foundation ▪ 2007
Nominated Project Kaleidoscope Faculty for the 21st Century Class of 2007

Project Kaleidoscope ▪ 2007
Outstanding achievement in new competitive research awards

Tulane University Health Sciences Center Board of Governors ▪ 2004
National Research Service Award – Postdoctoral Fellow

National Institutes of Health ▪ 1996

Publications

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Schieffelin JS, Costin JM, Nicholson CO, Orgeron NM, Fontaine KA, Isern S, Michael SF, Robinson JE. “Neutralizing and non-neutralizing human monoclonal antibodies against dengue virus E protein from a naturally infected patient”, Virology Journal 2010, 7:28. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829534/pdf/1743-422X-7-28.pdf

Costin JM, Jenwitheesuk E, Rees CR, Hunsperger E, Conrads K, Fontaine KA, Isern S, Samudrala R, Michael SF. “Structural Optimization and De Novo Design of Dengue Virus Entry Inhibitory Peptides”, PLoS Neglected Tropical Diseases, 2010 4(6): e721. doi:10.1371/journal.pntd.0000721.

Nicholson CO, Costin JM, Rowe DK, Lin L, Jenwitheesuk E, Samudrala R, Isern S, Michael SF. “Viral entry inhibitors block dengue antibody-dependent enhancement in vitro”, Antiviral Research 89:71–74 (2011).

Graham AS, Pruszynski CA, Hribar LJ, DeMay DJ, Tambasco AN, Hartley AE, Fussell EM, Michael SF, Isern S. “Mosquito-associated dengue virus, Key West, Florida, USA, 2010”, Emerging Infectious Diseases, 2011 vol. 17, no. 11, 2074-2075 http://dx.doi.org/10.3201/eid1711.110419

Costin JM, Zaitseva E, Kahle KM, Nicholson CO, Rowe DK, Graham AS, Bazzone LE, Hogancamp G, Figueroa Sierra M, Fong RH, Yang S-T, Lin L, Robinson JE, Doranz BJ, Chernomordik LV, Michael SF, Schieffelin JS, Isern S. “Mechanistic study of broadly neutralizing human monoclonal antibodies against dengue virus that target the fusion loop”, Journal of Virology 87:52-60 (2013).

Muyanja E, Ssemaganda A, NGauv P, Cubas R, Perrin H, Srinivasan D, Canderan G, Lawson B, Kopycinski J, Graham AS, Rowe DK, Smith MJ, Isern S, Michael S, Silvestri G, Vanderford TH, Castro E, Pantaleo G, Singer J, Gillmour J, Kiwanuka N, Nanvubya A, Schmidt C, Birungi J, Cox J, Haddad EK, Kaleebu P, Fast P, Sekaly R-P, Trautmann L. “Immune activation alters cellular and humoral responses to yellow fever 17D vaccine”. Journal of Clinical Investigation doi:10.1172/JCI75429 (2014).

Teets FD, Ramgopal MN, Sweeney KD, Graham AS, Michael SF, Isern S. “Origin of the dengue virus outbreak in Martin County, Florida, USA 2013”. Virology Reports, http://dx.doi.org/10.1016/j.virep.2014.05.001 (2014).

Pope WH, Bowman CA, Russell DA, Jacobs-Sera D, Asai DJ, Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science (SEA-PHAGES)*, Phage Hunters Integrating Research and Education (PHIRE), Mycobacterial Genetics Course (MGC), Cresawn SG, Jacobs Jr. WR, Hendrix RW, Lawrence JG, and Hatfull GF. “Whole Genome Comparison of a Large Collection of Mycobacteriophages Reveals a Continuum of Phage Genetic Diversity”, eLife 2015;4:e06416

Michael SF, Isern S, Garry RF, Samudrala R, Costin JM, Jenwitheesuk E. Patent No. 8,541,377, September 24, 2013. “Optimized dengue virus entry inhibitory peptide (DN81)”, awarded by the U.S. Patent and Trademark Office. Foreign patent applications: Africa, Australia, Bolivia, China, Columbia, Costa Rica, Dominican Republic, Ecuador, El Salvador, Europe, Guatemala, Haiti, Hong Kong, India, Indonesia, New Guinea, Philippines, Seychelles, Vietnam.

Michael SF, Isern S, Costin JM, Samudrala R, Jenwitheesuk E. Patent No. 8,637,472, January 28, 2014. “Optimized dengue virus entry inhibitory peptide (10AN)”, awarded by the U.S. Patent and Trademark Office.

Memberships

Vaccines Against Microbial Diseases Study Section, National Institutes of Health Center for Scientific Review, Member; 2015 - present

American Society for Microbiology, Member; 2013 - present

Florida Mosquito Control Association, Member; 2011 - present

American Society for Virology, Member; 2011 - present

American Association for the Advancement of Science, Member; 1993 - present

Peer Review Positions

Vaccines Against Microbial Diseases Study Section, Member, National Institutes of Health Center for Scientific Review; 2013 - 2016

Special Emphasis Panel/Scientific Review Group 2012/05 ZAI1 RWM-I (M2) 1, National Institutes of Health Center for Scientific Review; 2012 - 2012

Vaccines against Microbial Diseases Study Section, National Institutes of Health Center for Scientific Review; 2011 - 2011

SBIR/STTR Non-HIV Microbial Vaccine Development Study Section, National Institutes of Health Center for Scientific Review; 2011 - 2011

Scholarships in Science, Technology, Engineering, and Mathematics (S-STEM) Program Panel, National Science Foundation; 2008 - 2011

Advisory Panel for Increasing the Participation and Advancement of Women in Academic Science and Engineering Careers (ADVANCE), National Science Foundation; 2003 - 2003

Professional Presentations

Preventing Dengue Virus Entry; International Seminar Programme, Seminars in Virology; Section of Medical Virology, University Medical Center Groningen, Groningen, The Netherlands; 2010

Surveillance of Mosquito Populations for Dengue Virus in Monroe County, Florida in 2010-2011; 30th Annual Meeting American Society for Virology, University of Minnesota, Minneapolis, MN; American Society for Virology; 2011

Origin of Dengue Virus from Mosquitoes in Key West, Florida, 2010; Florida Mosquito Control Association 83rd Annual Meeting, Jacksonville, FL; Florida Mosquito Control Association; 2011

Development and Characterization of Dengue Virus Peptide Entry Inhibitors; A Re-Emerging Challenge: New Opportunities for Dengue Research Collaboration in the Americas, San Juan, PR; National Institutes of Allergy and Infectious Diseases and Centers for Disease Control and Prevention; 2011

Other Professional Activities

Course Director, Howard Hughes Medical Institute Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science (SEA-PHAGES) Virus Discovery Workshops (In Situ), University of Maryland Baltimore County, Baltimore, MD - 2015 to present

Stories

Researchers Discover Unreported Zika Outbreak in Cuba

#ZikaLately

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Search Google Scholar for Sharon Isern

Contact Information

sisern@fgcu.edu

239-590-7438

10501 FGCU Boulevard South
Fort Myers, FL 33965

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Sharon Isern

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