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Adaptive Optics Ophthalmic Imager Without Wavefront Sensor or Correction

Researchers at the University of South Florida have developed a novel adaptive optics ophthalmic imager that does not require the use of separate hardware devices, which are essential to con-ventional systems. This will ultimately reduce manufacturing and mainte-nance costs.

Imaging of the eye is important both in order to understand the process of vision and to correct or repair any defects in the vision system. The pro-cess is, however, challenging in several respects. For example, the relative-ly small aperture of the pupil and low reflectivity of the retina, limits the amount of light available for imaging with an external instrument. Current technology of adaptive optics (AO) solves this problem by employing a wavefront sensor to measure the aberration and a wavefront corrector to compensate for the aberration. However, these components require a high degree of delicate alignment and maintenance, constrain resolution, dynamic range, and speed, as well as drive up costs.

Our inventors have developed a new adaptive Optics system that dispens-es with wavefront sensor and corrector. This novel system replaces the above mentioned hardware components with numerical processing for wavefront measurement and compensation of aberration through princi-ples of digital holography. The wavefront sensing and correction has al-most full resolution of the CCD camera. In addition, the new aberration correction system can be easily incorporated into a conventional fundus camera to achieve high resolution imaging of retinal cone mosaic. It can also generate profiles of retinal vesculature and measurement of blood flow, provide real time profiles of ocular abberation during refractive sur-gery (Lasik), and generate three-dimensional map of intraocular debris.

Research Terms: Technology > Imaging Technology
Physical Sciences > Optics
Keywords: Engineering & Software, Optics/Imaging;
Technology Information URL:
University: University of South Florida
Tech Transfer URL:

Associated Patents

Patent Name: Adaptive optics ophthalmic imager without wavefront sensor or wavefront corrector
Patent Number: US Patent 9,179,841
Patent Status: Issued
Issue Date: November 10, 2015
Patent Record: View full record at google patents
View full record at United States Patent and Trademark Office
Patent Inventors:

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