-
"Short?term aerobic exercise prevents development of glucocorticoid myopathic features in aged skeletal muscle in a sex?dependent manner"
2024 ▪
The Journal of Physiology
-
"Post?translational modifications of vertebrate striated muscle myosin heavy chains"
2024 ▪
Cytoskeleton
-
"Troponin Structural Dynamics in the Native Cardiac Thin Filament Revealed by Cryo Electron Microscopy"
2024 ▪
Journal of Molecular Biology
-
"A missense variant in the Z-disc protein ?-actinin 2: Evidence for a sarcomere protein at the nexus of thick and thin filament regulation"
2024 ▪
Biophysical Journal
Isabella Leite Coscarella;
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Weikang Ma;
Bjorn C. Knollmann;
Thomas C. Irving;
Jeffrey Schmeckpeper;
Xuan Fang;
Payton A. Spran;
Aida Rahimi Kahmini;
M. Benjamin Shoemaker;
James B. Atkinson;
Peter M. Kekenes-Huskey;
Michelle C. Rodriguez Garcia;
-
"Cardiac troponin C N-helix deletion in mouse heart"
2024 ▪
Biophysical Journal
-
"Characterization of LV function using myocardial strain analysis in cardiac TnC-A8V mouse model"
2024 ▪
Biophysical Journal
-
"HCM- and DCM-associated TNNT2 sarcomeric variants induce divergent nucleus remodeling in human iPSC-CMs"
2024 ▪
Biophysical Journal
-
"Ryanodine receptor?associated myopathies: What's myosin got to do with it?"
2023 ▪
Acta Physiologica
-
"Disruption of Z-Disc Function Promotes Mechanical Dysfunction in Human Myocardium: Evidence for a Dual Myofilament Modulatory Role by Alpha-Actinin 2"
2023 ▪
International Journal of Molecular Sciences
Isabella Leite Coscarella;
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Weikang Ma;
Bjorn C. Knollmann;
Thomas C. Irving;
Michelle Rodriguez Garcia;
Jeffrey Schmeckpeper;
Xuan Fang;
Payton A. Spran;
Shengyao Yuan;
Lin Qi;
Aida Rahimi Kahmini;
M. Benjamin Shoemaker;
James B. Atkinson;
Peter M. Kekenes-Huskey;
-
"Nucleus Mechanosensing in Cardiomyocytes"
2023 ▪
International Journal of Molecular Sciences
-
"Creatine Kinase Equilibration and ?GATP over an Extended Range of Physiological Conditions: Implications for Cellular Energetics, Signaling, and Muscle Performance"
2023 ▪
International Journal of Molecular Sciences
P. Bryant Chase;
Robert W. Wiseman;
T. W. Beck;
Tyler R. Reinoso;
Yun Shi;
Caleb Micah Brown;
Jeffrey John Brault;
-
"The duration of glucocorticoid treatment alters the anabolic response to high-force muscle contractions"
2023 ▪
Journal of Applied Physiology
-
"Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function"
2023 ▪
Proceedings of the National Academy of Sciences
Isabella Leite Coscarella;
P. Bryant Chase;
Jose R. Pinto;
Vitold E. Galkin;
Maicon Landim-Vieira;
Weikang Ma;
Taejeong Song;
Hosna Rastegarpouyani;
Henry Gong;
Sylvia J. P. Bogaards;
Stefan P. Conijn;
Coen A. C. Ottenheijm;
Hyun S. Hwang;
Maria Papadaki;
Bjorn C. Knollmann;
Sakthivel Sadayappan;
Thomas C. Irving;
-
"Abnormal kinetics of contraction caused by an ?-actinin 2 missense variant in the EF-3-4 hand domain in human myocardium"
2023 ▪
Biophysical Journal
Isabella Leite Coscarella;
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Weikang Ma;
Bjorn C. Knollmann;
Thomas C. Irving;
Jeffrey Schmeckpeper;
Xuan Fang;
Aida Rahimi Kahmini;
M. Benjamin Shoemaker;
James B. Atkinson;
Peter M. Kekenes-Huskey;
Michelle C. Rodriguez Garcia;
Lili Wang;
-
"Computational modeling of cooperative regulation of both strands in thin filaments"
2023 ▪
Biophysical Journal
-
"Dissecting the mechanisms by which a pathogenic variant in cardiac TnT tail domain leads to disturbed myofilament performance"
2023 ▪
Biophysical Journal
P. Bryant Chase;
Jose R. Pinto;
Vitold E. Galkin;
Maicon Landim-Vieira;
Weikang Ma;
Taejeong Song;
Hosna Rastegarpouyani;
Henry Gong;
Coen A. C. Ottenheijm;
Maria Papadaki;
Bjorn C. Knollmann;
Sakthivel Sadayappan;
Thomas C. Irving;
Hyun Seok Hwang;
-
"HCM and DCM associated TNNT2 sarcomeric variants induce nucleus remodeling in human iPSC-CMs"
2023 ▪
Biophysical Journal
-
"Investigating the sarcolemma-sarcomere connection and force transmission in the heart"
2023 ▪
Biophysical Journal
-
"Protein densitometry profiling in mouse hearts carrying an HCM cardiac troponin T mutation"
2023 ▪
Biophysical Journal
-
"The structure of the junction region of the native cardiac thin filament"
2023 ▪
Biophysical Journal
-
"High-resolution cryo-EM structure of the junction region of the native cardiac thin filament in relaxed state"
2022 ▪
PNAS Nexus
-
"Post-translational modification patterns on ?-myosin heavy chain are altered in ischemic and nonischemic human hearts"
2022 ▪
eLife
-
"Author response: Post-translational modification patterns on ?-myosin heavy chain are altered in ischemic and nonischemic human hearts"
2022 ▪
-
"Human cardiac troponin T amino terminus is required for inhibition and cooperative activation of Ca2+-dependent thin filament sliding"
2022 ▪
Biophysical Journal
P. Bryant Chase;
Brenda Schoffstall;
Fang Wang;
Vincent A. LaBarbera;
Yun Shi;
Lauren E. Kessler;
Linda Stroud;
Quinton R. Sparrow;
-
"Hypertrophic and dilated cardiomyopathy-associatedTNNT2 pathogenic variants induce nucleus remodeling in hiPSC-CM models"
2022 ▪
Biophysical Journal
-
"Mechanism(s) of regulation of the cardiac thin filament: new perspectives for a longstanding enigma"
2022 ▪
Biophysical Journal
-
"Modeling force redevelopment as a response to thin filament activation time"
2022 ▪
Biophysical Journal
-
"Role of cardiac alpha-actinin 2 pathogenic variant in human myocardium mechanics"
2022 ▪
Biophysical Journal
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Bjorn C. Knollmann;
Jeffrey Schmeckpeper;
M. Benjamin Shoemaker;
Michelle C. Rodriguez Garcia;
Lili Wang;
-
"The HCM I79N pathogenic variant in cardiac TNT induces thick filament malfunction and myofilament lattice rearrangement"
2022 ▪
Biophysical Journal
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Weikang Ma;
Taejeong Song;
Henry Gong;
Coen A. C. Ottenheijm;
Bjorn C. Knollmann;
Sakthivel Sadayappan;
Thomas C. Irving;
Hyun Seok Hwang;
Maria Papadaki;
-
"Abstract P417: Cardiomyopathy-associated Variant In Troponin T Tail Domain Promotes Disruption Of Both Frank-starling Mechanism And Cardiac Myofilament Performance"
2021 ▪
Circulation Research
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Weikang Ma;
Taejeong Song;
Bjorn C. Knollmann;
Sakthivel Sadayappan;
Thomas C. Irving;
Hyun Seok Hwang;
Coen Ottenheijm;
-
"Abstract P421: Analysis Of The Functional Relevance Of Human Beta-myosin Heavy Chain Post-translational Modifications"
2021 ▪
Circulation Research
-
"Abstract P432: Alpha-actinin 2 Missense Variant And Its Role In Cardiac Muscle Force Production And Diastolic Dysfunction"
2021 ▪
Circulation Research
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Bjorn C. Knollmann;
Jeffrey Schmeckpeper;
Michelle C. Rodriguez Garcia;
Lili Wang;
Ben B Shoemaker;
-
"Systemic delivery of a mitochondria targeted antioxidant partially preserves limb muscle mass and grip strength in response to androgen deprivation"
2021 ▪
Molecular and Cellular Endocrinology
-
"Mandibular muscle troponin of the Florida carpenter ant Camponotus floridanus: extending our insights into invertebrate Ca2+ regulation"
2021 ▪
Journal of Muscle Research and Cell Motility
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Yun Shi;
Julia P. Bethea;
Hannah L. Hetzel-Ebben;
Ross J. Mayper;
Regan L. Williams;
Lauren E. Kessler;
Amanda M. Ruiz;
Kathryn Gargiulo;
Jennifer S. M. Rose;
Grayson Platt;
Brian K. Washburn;
-
"The structure of the native cardiac thin filament at systolic Ca 2+ levels"
2021 ▪
Proceedings of the National Academy of Sciences
-
"Conditional Knock-Out of Cardiac Myosin Light Chain Kinase Ameliorates Hypertrophic Cardiomyopathy Phenotype in a Murine Model"
2021 ▪
Biophysical Journal
-
"Genetic Variants and Post-Translational Modifications of Cardiac Troponin C: Insights from the Public Databases"
2021 ▪
Biophysical Journal
-
"Mandibular Muscle Troponin of the Florida Carpenter Ant Camponotus floridanus: Extending Our Insights into Invertebrate Ca2+ Regulation"
2021 ▪
Biophysical Journal
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Yun Shi;
Julia P. Bethea;
Hannah L. Hetzel-Ebben;
Ross J. Mayper;
Regan L. Williams;
Lauren E. Kessler;
Amanda M. Ruiz;
Kathryn Gargiulo;
Jennifer S. M. Rose;
Grayson Platt;
Brian K. Washburn;
-
"Mechanical Force Rather Than Strong Binding Intermediates Extends Activation of Regulated Actin"
2021 ▪
Biophysical Journal
-
"Modulation of Cardiac Thin Filament Azimuthal Rigidity by Calcium and Cross-Bridges"
2021 ▪
Biophysical Journal
-
"Post-Translational Modifications in Human Beta Myosin Heavy Chain"
2021 ▪
Biophysical Journal
-
"Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy"
2021 ▪
Chemical Science
P. Bryant Chase;
Jose R. Pinto;
Vitold E. Galkin;
Maicon Landim-Vieira;
Jamie R. Johnston;
Michelle S. Parvatiyar;
Mayra A. Marques;
Guilherme A.P. de Oliveira;
Adolfo H. Moraes;
Jerson L. Silva;
Karissa M. Dieseldorff Jones;
Isela C. Valera;
Peter M. Kekenes-Huskey;
Bin Sun;
Elio A. Cino;
-
"A comprehensive guide to genetic variants and post-translational modifications of cardiac troponin C"
2020 ▪
Journal of Muscle Research and Cell Motility
-
"Association between ELABELA Serum Concentrations in First Trimester and Pregnancy-Induced Hypertension"
2020 ▪
BioMed Research International
P. Bryant Chase;
Shujuan Ma;
Chuhao Guo;
Jiayue Zhang;
Sisi Long;
Hongzhuan Tan;
Yiping You;
-
"Mechanical contribution to muscle thin filament activation"
2020 ▪
Journal of Biological Chemistry
-
"Meta-analysis of cardiomyopathy-associated variants in troponin genes identifies loci and intragenic hot spots that are associated with worse clinical outcomes"
2020 ▪
Journal of Molecular and Cellular Cardiology
-
"Sexual dimorphism in cardiac transcriptome associated with a troponin C murine model of hypertrophic cardiomyopathy"
2020 ▪
Physiological Reports
-
"Calcium Regulates Average Time and not Velocity a Thin Filament Moves"
2020 ▪
Biophysical Journal
-
"Connecting Cardiac Sarcolemma Protein Content with Sarcomeric Function"
2020 ▪
Biophysical Journal
-
"Measurements of Actin Layer Lines in Permeabilized Heart Tissue Reveal New Structural Properties of the Cardiac Thin Filament"
2020 ▪
Biophysical Journal
-
"Osmotic Compression Influences Cross-Bridge Detachment Rate in Transgenic Hypertrophic Cardiomyopathy Variant Hctnt-I79N and Non-Transgenic Mouse Cardiac Muscle"
2020 ▪
Biophysical Journal
-
"Reduced Beta Myosin Heavy Chain K213 Acetylation and T215 Phosphorylation in Human Heart Failure"
2020 ▪
Biophysical Journal
-
"Sex Differences in Regulating the Cardiac Transcriptome within a Murine Model for Hypertrophic Cardiomyopathy"
2020 ▪
Biophysical Journal
-
"Familial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants"
2020 ▪
Frontiers in Physiology
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Jamie R. Johnston;
Weizhen Ji;
Emily K. Mis;
Joshua Tijerino;
Michele Spencer-Manzon;
Lauren Jeffries;
E. Kevin Hall;
David Panisello-Manterola;
Mustafa K. Khokha;
Engin Deniz;
Saquib A. Lakhani;
-
"The intrinsically disordered C terminus of troponin T binds to troponin C to modulate myocardial force generation"
2019 ▪
Journal of Biological Chemistry
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Jamie R. Johnston;
Huan He;
David Gonzalez-Martinez;
Mayra A. Marques;
Guilherme A.P. de Oliveira;
Adolfo H. Moraes;
Anwar Iqbal;
Yael Wilnai;
Einat Birk;
Nili Zucker;
Jerson L. Silva;
-
"Supplementary Data for Publication Titled "Sex differences in regulating the cardiac transcriptome within a murine model for hypertrophic cardiomyopathy""
2019 ▪
-
"A Dynamic Situation with Uncertainty: Multiscale Modeling of Cardiac Thin-Filament Ca2+ Regulation"
2019 ▪
Biophysical Journal
-
"Cardiomyocyte nuclearity and ploidy: when is double trouble?"
2019 ▪
Journal of Muscle Research and Cell Motility
-
"Elastic domains of giant proteins in striated muscle: Modeling compliance with rulers"
2019 ▪
The Journal of General Physiology
-
"Annulment of Cardiac Muscle Length-Dependent Force Activation in Transgenic Mice Bearing the HcTnT-I79N Mutation"
2019 ▪
Biophysical Journal
-
"Dynamic and Structural Allosteric Events between the D/E Linker and N-Domain of Cardiac Troponin C Reveal a Novel Mechanism for Cardiac Muscle Regulation"
2019 ▪
Biophysical Journal
P. Bryant Chase;
Jose R. Pinto;
Mayra A. Marques;
Guilherme A.P. de Oliveira;
Adolfo H. Moraes;
Jerson L. Silva;
Karissa M. Dieseldorff Jones;
Elio A. Cino;
Maicom Landim-Vieira;
-
"Thin Filament Regulation Blends Thermodynamic and Mechanical Mechanisms"
2019 ▪
Biophysical Journal
-
"Structural and functional impact of troponin C-mediated Ca2+ sensitization on myofilament lattice spacing and cross-bridge mechanics in mouse cardiac muscle"
2018 ▪
Journal of Molecular and Cellular Cardiology
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Jamie R. Johnston;
Weikang Ma;
Thomas C. Irving;
David Gonzalez-Martinez;
Olga Antipova;
Omar Awan;
-
"Aberrant Cardiac Muscle Mechanics in a Hypertrophic Cardiomyopathy Troponin T ILE79ASN Transgenic Mouse"
2018 ▪
Biophysical Journal
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Bjorn C. Knollmann;
David Gonzalez-Martinez;
Hyun Seok Hwang;
Karissa M. Dieseldorff Jones;
Yeojung Koh;
-
"Cardiac Thin Filament-Mediated Calcium Sensitization Modulates Cross-Bridge Kinetics"
2018 ▪
Biophysical Journal
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Jamie R. Johnston;
Weikang Ma;
Thomas C. Irving;
David Gonzalez-Martinez;
Omar Awan;
Olga A. Antipova;
-
"Clinical and Biophysical Characterization of a Mutation in the N-Helix Region of Cardiac Troponin C: Evidence for an Allosteric Mechanism of Contractile Dysfunction"
2018 ▪
Biophysical Journal
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Jamie R. Johnston;
David Gonzalez-Martinez;
Mayra A. Marques;
Guilherme A.P. de Oliveira;
Adolfo H. Moraes;
Yael Wilnai;
Einat Birk;
Nili Zucker;
Jerson L. Silva;
-
"Is Thin Filament Movement Switched On and Off by a Thermodynamic Process Alone"
2018 ▪
Biophysical Journal
-
"Troponin through the looking-glass: emerging roles beyond regulation of striated muscle contraction"
2017 ▪
Oncotarget
-
"Hypertrophic Cardiomyopathy Cardiac Troponin C Mutations Differentially Affect Slow Skeletal and Cardiac Muscle Regulation"
2017 ▪
Frontiers in Physiology
-
"A Novel DCM-Associated Mutation in the N-Helix of Cardiac Troponin C Exhibits Impaired Contractile Kinetics and Reduced Ca 2+ -Sensitivity In Vitro"
2017 ▪
Biophysical Journal
-
"Abnormal Cardiac Cross-Bridge Kinetics in a Troponin T ILE79ASN Transgenic Mouse Model"
2017 ▪
Biophysical Journal
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Bjorn C. Knollmann;
David Gonzalez-Martinez;
Hyun Seok Hwang;
Karissa M. Dieseldorff Jones;
Kwangjun Lee;
Yeojung Koh;
-
"Thin Filament-Mediated Modulation of Mouse Cardiac Cross-Bridge Kinetics by Ca 2+ -Sensitizing Mutation CTNC-A8V or Bepridil"
2017 ▪
Biophysical Journal
P. Bryant Chase;
Jose R. Pinto;
Maicon Landim-Vieira;
Jamie R. Johnston;
Weikang Ma;
Thomas C. Irving;
David Gonzalez-Martinez;
Omar Awan;
Olga A. Antipova;
Brittany Griffin;
-
"Cooccurrence of Obesity, Osteoporosis, and Sarcopenia in the Ovariectomized Rat"
2017 ▪
Journal of Aging Research
-
"The Cooccurrence of Obesity, Osteoporosis, and Sarcopenia in the Ovariectomized Rat: A Study for Modeling Osteosarcopenic Obesity in Rodents"
2017 ▪
Journal of Aging Research
-
"Will you still need me (Ca2+, TnT, and DHPR), will you still cleave me (calpain), when I'm 64?"
2016 ▪
Aging Cell
-
"Fluorescent Protein-Based Ca2+ Sensor Reveals Global, Divalent Cation-Dependent Conformational Changes in Cardiac Troponin C"
2016 ▪
PLoS ONE
-
"Commentary: Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised ?-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy"
2016 ▪
Frontiers in Physiology
-
"Role of cardiac troponin I carboxy terminal mobile domain and linker sequence in regulating cardiac contraction"
2016 ▪
Archives of Biochemistry and Biophysics
-
"The functional significance of the last 5 residues of the C-terminus of cardiac troponin I"
2016 ▪
Archives of Biochemistry and Biophysics
P. Bryant Chase;
Jennifer E. Gilda;
Qian Xu;
Margaret E. Martinez;
Susan T. Nguyen;
Aldrin V. Gomes;
-
"Simultaneous Measurement of Force and Lattice Spacing in Skinned Cardiac Fibers"
2016 ▪
Biophysical Journal
-
"sliding , G203S, K206Q) enhance filament ? troponin I (K183 Familial hypertrophic cardiomyopathy mutations in"
2015 ▪
P. Bryant Chase;
Michael Regnier;
Anthony J. Rivera;
Albert M. Gordon;
D.A. Martyn;
Bernhard Brenner;
Theresia Kraft;
Chien-Kao Wang;
Albert Wang;
William Lehman;
D. Brian;
Victoria Hatch;
Roger Craig;
Anne M. Murphy;
Jennifer E. Van Eyk;
F. Steven Korte;
Erik R. Feest;
Maria V. Razumova;
An-Yue Tu;
-
"Frequency dependence of power and its implications for contractile function of muscle fibers from the digital flexors of horses"
2014 ▪
Physiological Reports
P. Bryant Chase;
M. T. Butcher;
J. W. Hermanson;
J. E. A. Bertram;
Douglas A. Syme;
-
"Age?related differences in select systemic and local biomarkers affecting body composition in ovariectomized rats (1031.5)"
2014 ▪
The FASEB Journal
-
"Ca2+-regulatory function of the inhibitory peptide region of cardiac troponin I is aided by the C-terminus of cardiac troponin T: Effects of familial hypertrophic cardiomyopathy mutations cTnI R145G and cTnT R278C, alone and in combination, on filament sliding"
2014 ▪
Archives of Biochemistry and Biophysics
-
"Ca2+-Regulatory Function of the Inhibitory Peptide Region of Cardiac Troponin I is Aided by the C-Terminus of Cardiac Troponin T: Effects of FHC Mutations Ctni R145G and Ctnt R278C, Alone and in Combination, on Filament Sliding"
2014 ▪
Biophysical Journal
-
"Nuclear tropomyosin and troponin in striated muscle: new roles in a new locale?"
2013 ▪
Journal of Muscle Research and Cell Motility
-
"Estrogen replacement prevents ovariectomy?induced muscle degradation via lowering local IGF?1 production"
2013 ▪
The FASEB Journal
-
"Slowed Dynamics of Thin Filament Regulatory Units Reduces Ca2+-Sensitivity of Cardiac Biomechanical Function"
2013 ▪
Cellular and Molecular Bioengineering
P. Bryant Chase;
Aya K. Takeda;
Campion K P Loong;
Myriam A Badr;
Jordan S. Rogers;
-
"Human Cardiac Troponin C undergoes Global Conformational Changes in Response to Divalent Cation Binding: Solution Studies of Fluorescent Protein Constructs by FRET and Analytical Ultracentrifugation"
2013 ▪
Biophysical Journal
-
"Muscle fatigue and muscle weakness: what we know and what we wish we did"
2013 ▪
Frontiers in Physiology
-
"Familial hypertrophic cardiomyopathy related E180G mutation increases flexibility of human cardiac ??tropomyosin"
2012 ▪
FEBS Letters
-
"Persistence Length of Human Cardiac ?-Tropomyosin Measured by Single Molecule Direct Probe Microscopy"
2012 ▪
PLoS ONE
-
"Bionanotechnology and Nanomedicine"
2012 ▪
Journal of Biomedicine and Biotechnology
-
"Detection of Target ssDNA Using a Microfabricated Hall Magnetometer with Correlated Optical Readout"
2012 ▪
Journal of Biomedicine and Biotechnology
-
"Micromechanical Thermal Assays of Ca2+-Regulated Thin-Filament Function and Modulation by Hypertrophic Cardiomyopathy Mutants of Human Cardiac Troponin"
2012 ▪
Journal of Biomedicine and Biotechnology
-
"Persistence Length of Human Cardiac ?-Tropomyosin Implies Near-Neighbor Cooperative Activation of Cardiac Thin Filaments"
2012 ▪
Biophysical Journal
-
"Tropomyosin Flexural Rigidity and Single Ca2+ Regulatory Unit Dynamics: Implications for Cooperative Regulation of Cardiac Muscle Contraction and Cardiomyocyte Hypertrophy"
2012 ▪
Frontiers in Physiology
-
"Nuclear cardiac troponin and tropomyosin are expressed early in cardiac differentiation of rat mesenchymal stem cells"
2011 ▪
Differentiation
-
"Age-related changes in rat bone-marrow mesenchymal stem cell plasticity"
2011 ▪
BMC Cell Biology
-
"Functionalized SnO2 nanobelt field-effect transistor sensors for label-free detection of cardiac troponin"
2011 ▪
Biosensors and Bioelectronics
-
"Interaction Between Troponin and Myosin Enhances Contractile Activity of Myosin in Cardiac Muscle"
2011 ▪
DNA and Cell Biology
P. Bryant Chase;
Nancy L. Meyer;
Aya K. Takeda;
Nicolas M. Brunet;
Brenda Schoffstall;
Vincent A. LaBarbera;
Belinda J. Gavino;
Lauren Herring;
Sara Heshmati;
Brittany H. Kraft;
Vanessa Inchausti;
Danamarie Moonoo;
-
"Several cardiomyopathy causing mutations on tropomyosin either destabilize the active state of actomyosin or alter the binding properties of tropomyosin"
2011 ▪
Biochemical and Biophysical Research Communications
-
"Enhanced Active Cross-Bridges during Diastole: Molecular Pathogenesis of Tropomyosin's HCM Mutations"
2011 ▪
Biophysical Journal
-
"Flexibility Change in Human Cardiac ?-Tropomyosin E180G Mutant: Possible Link to Cardiac Hypertrophy"
2011 ▪
Biophysical Journal
-
"The Effect of Dilated Cardiomyopathy (DCM) Mutations of Tropomyosin on Force Generation and Cross-Bridge Kinetics in Thin-Filament Reconstituted Bovine Cardiac Muscle Fibers"
2011 ▪
Biophysical Journal
-
"Facilitated Cross-Bridge Interactions with Thin Filaments by Familial Hypertrophic Cardiomyopathy Mutations in?-Tropomyosin"
2011 ▪
BioMed Research International
-
"Dynamic micro-Hall detection of superparamagnetic beads in a microfluidic channel"
2010 ▪
Journal of Magnetism and Magnetic Materials
-
"Contractile properties of muscle fibers from the deep and superficial digital flexors of horses"
2010 ▪
AJP Regulatory Integrative and Comparative Physiology
P. Bryant Chase;
Nicolas M. Brunet;
Amanda Clark;
M. T. Butcher;
J. W. Hermanson;
J. E. A. Bertram;
-
"Label-free detection of DNA hybridization using InAs $\mu $-Hall sensors"
2010 ▪
Bulletin of the American Physical Society
-
"Magnetic and Fluorescence Detection of Hybridized DNA Assemblies Immobilized onto a Hall Device"
2010 ▪
Biophysical Journal
-
"Mechanical Properties of Human Cardiac Tropomyosin in Familial Hypertrophic Cardiomyopathy (FHC) Probed by Atomic Force Microscopy"
2010 ▪
Biophysical Journal
-
"Molecular Function of the C-terminal Domain of Cardiac Troponin I"
2010 ▪
Biophysical Journal
P. Bryant Chase;
Nancy L. Meyer;
Nicolas M. Brunet;
Brenda Schoffstall;
Vincent A. LaBarbera;
Vanessa Inchausti;
Danamarie Moonoo;
-
"The Effect of Hypertrophic Cardiomyopathy (HCM) Mutations of Tropomyosin on Force Generation and Cross-Bridge Kinetics in Thin-Filament Reconstituted Bovine Cardiac Muscle Fibers"
2010 ▪
Biophysical Journal
-
"The detection of specific biomolecular interactions with micro-Hall magnetic sensors"
2009 ▪
Nanotechnology
-
"Magnetic detection of biotin-streptavidin binding using InAs quantum well $\mu $-Hall sensor"
2009 ▪
Bulletin of the American Physical Society
-
"Effects of Elevated Solvent Viscosity on Calcium Dependence of Cardiac Myofilament Contractility"
2009 ▪
Biophysical Journal
-
"Increased intracellular [dATP] enhances cardiac contraction in embryonic chick cardiomyocytes"
2008 ▪
Journal of Cellular Biochemistry
-
"InAs quantum well $\mu$-Hall sensors for magnetic biosensing"
2008 ▪
Bulletin of the American Physical Society
-
"Detection of specific biomolecular interactions with micro-hall magnetic sensors"
2008 ▪
Small
-
"Molecular Motor-Based Assays for Altered Nanomechanical Function of Ca2+-Regulatory Proteins in Cardiomyopathies"
2008 ▪
MRS Proceedings
-
"Selective Assembly and Guiding of Actomyosin Using Carbon Nanotube Network Monolayer Patterns"
2007 ▪
Langmuir
-
"Tropomyosin in the groove? Molecular insights into an inherited myopathy"
2007 ▪
The Journal of Physiology
-
"Thin?filament regulation of force redevelopment kinetics in rabbit skeletal muscle fibres"
2007 ▪
The Journal of Physiology
P. Bryant Chase;
Michael Regnier;
Anthony J. Rivera;
D.A. Martyn;
Alicia Moreno-Gonzalez;
Todd E. Gillis;
-
"Computational simulation of hypertrophic cardiomyopathy mutations in Troponin I: Influence of increased myofilament calcium sensitivity on isometric force, ATPase and [Ca2+]"
2006 ▪
Journal of Biomechanics
-
"Spatially explicit, nano-mechanical models of the muscle half-sarcomere: Implications for biomechanical tuning in atrophy and fatigue"
2006 ▪
Acta Astronautica
P. Bryant Chase;
Thomas L. Daniel;
Michael Regnier;
J. Michael Macpherson;
Aya Kataoka;
Bertrand C.W. Tanner;
Xiangrong Xu;
Qi Wang;
-
"Ca2+ sensitivity of regulated cardiac thin filament sliding does not depend on myosin isoform"
2006 ▪
The Journal of Physiology
P. Bryant Chase;
Nicolas M. Brunet;
Brenda Schoffstall;
Fang Wang;
Lisa A. Compton;
Victor F. Miller;
Shanedah Williams;
Alyson T. Barnes;
Lori A. McFadden;
Dianne W. Taylor;
Margaret Seavy;
Rani Dhanarajan;
-
"Selective Assembly and Alignment of Actin Filaments with Desired Polarity on Solid Substrates"
2006 ▪
Langmuir
-
"Positive Inotropic Effects of Low dATP/ATP Ratios on Mechanics and Kinetics of Porcine Cardiac Muscle"
2006 ▪
Biophysical Journal
-
"A7. Nanomechanical assays for detection of atlered protein function in cardiomyopathies"
2006 ▪
Journal of Molecular and Cellular Cardiology
-
"Packaging actomyosin-based biomolecular motor-driven devices for nanoactuator applications"
2005 ▪
IEEE Transactions on Advanced Packaging
P. Bryant Chase;
Peng Xiong;
Timothy S. Moerland;
Nicolas M. Brunet;
Goran Mihajlovi?;
Lori A. McFadden;
S von Molnár;
T.J. Grove;
K.A. Puckett;
-
"Effects of temperature, ionic strength and pH on the function of skeletal muscle myosin from a eurythermal fish, Fundulus heteroclitus"
2005 ▪
Journal of Muscle Research and Cell Motility
-
"Highly Selective Directed Assembly of Functional Actomyosin on Au Surfaces"
2005 ▪
Langmuir
P. Bryant Chase;
Pradeep Manandhar;
Justin R. Grubich;
Ling Huang;
John W. Hutchinson;
Seunghun Hong;
-
"The ?14 Mutation of Human Cardiac Troponin T Enhances ATPase Activity and Alters the Cooperative Binding of S1-ADP to Regulated Actin"
2004 ▪
Biochemistry
P. Bryant Chase;
Bernhard Brenner;
Joseph M. Chalovich;
Boris Gafurov;
Scott Fredricksen;
Anmei Cai;
-
"A Spatially Explicit Nanomechanical Model of the Half-Sarcomere: Myofilament Compliance Affects Ca2+-Activation"
2004 ▪
Annals of Biomedical Engineering
-
"Effects of Rapamycin on Cardiac and Skeletal Muscle Contraction and Crossbridge Cycling"
2004 ▪
Journal of Pharmacology and Experimental Therapeutics
-
"All-electrical switching and control mechanism for actomyosin-powered nanoactuators"
2004 ▪
Applied Physics Letters
-
"A reversible switch for actomyosin-based nanoactuators"
2004 ▪
Biophysical Journal
-
"An All-Electrical Switching and Control Mechanism for Actomyosin-Powered Nanoactuators"
2004 ▪
APS March Meeting Abstracts
P. Bryant Chase;
Peng Xiong;
Nicolas M. Brunet;
Goran Mihajlovi?;
Jelena Trbovi?;
Lori A. McFadden;
Shanedah T. Williams;
Stephan von Molnir;
-
"Actomyosin-Driven Motility on Patterned Polyelectrolyte Mono- and Multilayers"
2003 ▪
Nano Letters
-
"Ca2+ Regulation of Rabbit Skeletal Muscle Thin Filament Sliding: Role of Cross-Bridge Number"
2003 ▪
Biophysical Journal
P. Bryant Chase;
Z. Luo;
Michael Regnier;
Albert M. Gordon;
Ying Chen;
Bo Liang;
Chien-Kao Wang;
-
"Familial hypertrophic cardiomyopathy mutations in troponin I (K183?, G203S, K206Q) enhance filament sliding"
2003 ▪
Physiological Genomics
P. Bryant Chase;
Michael Regnier;
Anthony J. Rivera;
Albert M. Gordon;
D.A. Martyn;
Jan Köhler;
Ying Chen;
Bernhard Brenner;
Theresia Kraft;
Chien-Kao Wang;
-
"A Simple Model with Myofilament Compliance Predicts Activation-Dependent Crossbridge Kinetics in Skinned Skeletal Fibers"
2002 ▪
Biophysical Journal
-
"Thin filament near?neighbour regulatory unit interactions affect rabbit skeletal muscle steady?state force?Ca2+ relations"
2002 ▪
The Journal of Physiology
P. Bryant Chase;
Michael Regnier;
Anthony J. Rivera;
Chien?Kao Wang;
Mandy A. Bates;
Albert M. Gordon;
-
"Motility Assays of Calcium Regulation of Actin Filaments"
2002 ▪
Results and problems in cell differentiation
-
"Dimethyl sulphoxide enhances the effects of Pi in myofibrils and inhibits the activity of rabbit skeletal muscle contractile proteins"
2001 ▪
Biochemical Journal
P. Bryant Chase;
Ying Chen;
M.M. Sorenson;
Ana C. MARIANO;
Giani M.C. ALEXANDRE;
Leonardo C. SILVA;
Alexandre ROMEIRO;
Luiz Claudio CAMERON;
-
"Dimethyl sulphoxide enhances the effects of Pi in myofibrils and inhibits the activity of rabbit skeletal muscle contractile proteins"
2001 ▪
Biochemical Journal
P. Bryant Chase;
Ying Chen;
M.M. Sorenson;
Ana C. MARIANO;
Giani M.C. ALEXANDRE;
Leonardo C. SILVA;
Alexandre ROMEIRO;
Luiz Claudio CAMERON;
-
"2-Deoxy-ATP Enhances Contractility of Rat Cardiac Muscle"
2000 ▪
Circulation Research
-
"Viscosity and solute dependence of F-actin translocation by rabbit skeletal heavy meromyosin"
2000 ▪
AJP Cell Physiology
-
"Regulation of Skeletal Muscle Tension Redevelopment by Troponin C Constructs with Different Ca2+ Affinities"
1999 ▪
Biophysical Journal
P. Bryant Chase;
Michael Regnier;
Anthony J. Rivera;
L.B. Smillie;
M.M. Sorenson;
-
"Ca2+ and Cross-Bridge-Induced Changes in Troponin C in Skinned Skeletal Muscle Fibers: Effects of Force Inhibition"
1999 ▪
Biophysical Journal
-
"Contractile properties of rabbit psoas muscle fibres inhibited by beryllium fluoride."
1999 ▪
Journal of Muscle Research and Cell Motility
-
"Calcium Regulation of Tension Redevelopment Kinetics with 2-Deoxy-ATP or Low [ATP] in Rabbit Skeletal Muscle"
1998 ▪
Biophysical Journal
-
"Compliant Realignment of Binding Sites in Muscle: Transient Behavior and Mechanical Tuning"
1998 ▪
Biophysical Journal
-
"Calcium Regulation Of Actin Filament Speed In Vitro"
1998 ▪
APS
-
"Effect of Viscosity on Mechanics of Single, Skinned Fibers from Rabbit Psoas Muscle"
1998 ▪
Biophysical Journal
-
"Skeletal Muscle Regulatory Proteins Enhance F-Actin In Vitro Motility"
1998 ▪
Advances in experimental medicine and biology
-
"Calcium regulation of skeletal muscle thin filament motility in vitro"
1997 ▪
Biophysical Journal
-
"Calmidazolium alters Ca2+ regulation of tension redevelopment rate in skinned skeletal muscle"
1996 ▪
Biophysical Journal
-
"Effect of intracellular pH on force development depends on temperature in intact skeletal muscle from mouse"
1996 ▪
AJP Cell Physiology
-
"Phase 2 Tension Transients, Unlike VUS and kTR, are Faster at Submaximal Calcium Activation in Skinned Rabbit Psoas Muscle Fibers"
1995 ▪
Biophysical Journal
-
"Effect of physiological ADP concentrations on contraction of single skinned fibers from rabbit fast and slow muscles"
1995 ▪
AJP Cell Physiology
-
"Faster force transient kinetics at submaximal Ca2+ activation of skinned psoas fibers from rabbit"
1995 ▪
Biophysical Journal
-
"Isometric force redevelopment of skinned muscle fibers from rabbit activated with and without Ca2+"
1994 ▪
Biophysical Journal
-
"Unloaded shortening of skinned muscle fibers from rabbit activated with and without Ca2+"
1994 ▪
Biophysical Journal
P. Bryant Chase;
M.J. Kushmerick;
A.M. Gordon;
D.A. Martyn;
J.D. Hannon;
L.L. Huntsman;
-
"Activation dependence and kinetics of force and stiffness inhibition by aluminiofluoride, a slowly dissociating analogue of inorganic phosphate, in chemically skinned fibres from rabbit psoas muscle"
1994 ▪
Journal of Muscle Research and Cell Motility
-
"Calcium-independent activation of skeletal muscle fibers by a modified form of cardiac troponin C"
1993 ▪
Biophysical Journal
P. Bryant Chase;
M.J. Kushmerick;
A.M. Gordon;
D.A. Martyn;
J.D. Hannon;
L.L. Huntsman;
-
"Effects of inorganic phosphate analogues on stiffness and unloaded shortening of skinned muscle fibres from rabbit."
1993 ▪
The Journal of Physiology
-
"Antibody and peptide probes of interactions between the SH1-SH2 region of myosin subfragment 1 and actin's N-terminus"
1992 ▪
Biochemistry
-
"High-performance liquid chromatographic assays for free and phosphorylated derivatives of the creatine analogues ?-guanidopropionic acid and 1-carboxymethyl-2-iminoimidazolidine (cyclocreatine)"
1992 ▪
Analytical Biochemistry
P. Bryant Chase;
M.J. Kushmerick;
Robert W. Wiseman;
Timothy S. Moerland;
Rudolph Stuppard;
-
"Molecular charge dominates the inhibition of actomyosin in skinned muscle fibers by SH1 peptides"
1991 ▪
Biophysical Journal
-
"Competitive Inhibition of Maximum Ca-Activated Force in Skinned Muscle Fibers by Cationic Peptides from the SH-1 Region of Myosin Heavy Chain"
1991 ▪
Springer eBooks
-
"Effects of pH on contraction of rabbit fast and slow skeletal muscle fibers"
1988 ▪
Biophysical Journal
-
"Permeation and interaction of divalent cations in calcium channels of snail neurons."
1985 ▪
The Journal of General Physiology
-
"Calcium current activation kinetics in neurones of the snail Lymnaea stagnalis."
1984 ▪
The Journal of Physiology