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Matthew Disney
Institute Professor & Chair, Department Of Chemistry
SR-CHEM-DISNEY LAB | UF SCRIPPS BIOMEDICAL RESEARCH
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Chemistry
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Title
03-2030
Targeted degradation of RNAs by using small molecules
Targeted degradation of RNAs by using small molecules
NATL INST OF HLTH NC
07-2028
Novel mRNA degraders to target hypoxic tumor microenvironment
Novel mRNA degraders to target hypoxic tumor microenvironment
FL DEPT OF HLTH BANKHEAD-COLEY CANCER R
04-2028
Design of precision small molecules targeting RNA repeating transcripts to manipulate and study disease biology
Design of precision small molecules targeting RNA repeating transcripts to manipulate and study disease biology
NATL INST OF HLTH NIND
08-2027
Development of Clinical Candidates for the Treatment of Myotonic Dystrophy
Development of Clinical Candidates for the Treatment of Myotonic Dystrophy
US ARMY MED RES ACQUISITIO
11-2026
Small molecule degradation of tau mRNA
Small molecule degradation of tau mRNA
RAINWATER CHARITABLE FOUNDATION
08-2026
Targeting the RNA Repeat Expansion that Causes Myotonic Dystrophy Type 2
Targeting the RNA Repeat Expansion that Causes Myotonic Dystrophy Type 2
MUSCULAR DYSTROPHY ASS
06-2026
Design of small molecules that degrade the mRNA encoding a-synuclein
Design of small molecules that degrade the mRNA encoding a-synuclein
SPARK NS
12-2025
Developing Artificial Intelligence and Machine Learning Approaches to Identify and Optimize Small Molecule Medicines Targeting Oncogenic RNAs
Developing Artificial Intelligence and Machine Learning Approaches to Identify and Optimize Small Molecule Medicines Targeting Oncogenic RNAs
FL DEPT OF HLT
10-2025
Astellas Pharma Inc. bench fees for Dr. Ryuichi Sekioka
Astellas Pharma Inc. bench fees for Dr. Ryuichi Sekioka
ASTELLAS PHARMA US, IN
08-2025
Graduate Research Fellowship program (GRFP)
Graduate Research Fellowship program (GRFP)
NATL SCIENCE FO
08-2025
Design and evaluation of drug-like small molecules targeting repeat expansion (MDA 963835)
Design and evaluation of drug-like small molecules targeting repeat expansion (MDA 963835)
MUSCULAR DYSTROPHY ASS
06-2025
Small Molecule Targeting of mRNAs Encoding Proteins relevant for Cardiovascular, Renal and Metabolic Diseases
Small Molecule Targeting of mRNAs Encoding Proteins relevant for Cardiovascular, Renal and Metabolic Diseases
ASTRAZENEC
06-2025
CD33 Targeting Small Molecule Drug Discovery
CD33 Targeting Small Molecule Drug Discovery
EISAI
04-2025
Center for Antiviral Medicines & Pandemic Preparedness (CAMPP) - PROJECT 4
Center for Antiviral Medicines & Pandemic Preparedness (CAMPP) - PROJECT 4
NATL INST OF HLTH NIAI
04-2025
Development of outpatient antiviral cocktails against SARS-CoV-2 and other potential pandemic RNA viruses
Development of outpatient antiviral cocktails against SARS-CoV-2 and other potential pandemic RNA viruses
NATL INST OF HLTH NIAI
03-2025
Targeted degradation of RNAs by using small molecules
Targeted degradation of RNAs by using small molecules
NATL INST OF HLTH NC
03-2025
Targeting mRNAs that Contribute to Neurological Disease
Targeting mRNAs that Contribute to Neurological Disease
EXPANSION THERAPEUTICS
11-2024
Brain penetrant small molecules drugs that target tau pre-mRNA for degradation
Brain penetrant small molecules drugs that target tau pre-mRNA for degradation
RAINWATER CHARITABLE FOUNDATION
08-2024
Small Molecules That Target the RNAs That Cause Pulmonary Fibrosis and Polycystic Kidney Disease
Small Molecules That Target the RNAs That Cause Pulmonary Fibrosis and Polycystic Kidney Disease
US ARMY MED RES ACQUISITIO
10-2023
Pre-clinical evaluation of small molecules that rescue aberrant Tau mRNA splicing
Pre-clinical evaluation of small molecules that rescue aberrant Tau mRNA splicing
RAINWATER CHARITABLE FOUNDATION
10-2023
Targeting RNAs Associated with Tauopathies with Small Molecules
Targeting RNAs Associated with Tauopathies with Small Molecules
RAINWATER CHARITABLE FOUNDATION
08-2023
Expanding Ribonuclease Targeting Chimeras (RIBOTACs) to Advance Targeted Degradation of Disease-Causing RNAs
Expanding Ribonuclease Targeting Chimeras (RIBOTACs) to Advance Targeted Degradation of Disease-Causing RNAs
GENENTECH IN
08-2023
Design and Study of Small Molecules That Cleave the RNA That Causes Myotonic Dystrophy Type 1 (DM1)
Design and Study of Small Molecules That Cleave the RNA That Causes Myotonic Dystrophy Type 1 (DM1)
US ARMY MED RES ACQUISITIO
05-2023
RNA-Targeted Drug Discovery and Development for Parkinson's Disease
RNA-Targeted Drug Discovery and Development for Parkinson's Disease
NATL INST OF HLTH NIND
04-2023
Pathophysiology of genetically defined dementia and neurodegeneration: Defining therapeutic targets and pathways
Pathophysiology of genetically defined dementia and neurodegeneration: Defining therapeutic targets and pathways
NATL INST OF HLTH NIND
12-2022
Developing Pre-Clinical Candidates Against miRNAs Implicated in Autoimmune Diseases
Developing Pre-Clinical Candidates Against miRNAs Implicated in Autoimmune Diseases
EMD SERON
12-2022
Small Molecule Targeting of DUX4 mRNA for treatment of Fascioscapulohumeral Dystrophy (FSHD)
Small Molecule Targeting of DUX4 mRNA for treatment of Fascioscapulohumeral Dystrophy (FSHD)
PFIZER IN
Publications
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Co-Investigator Network
Eric Wang
Professor
University of Florida
Md-Molecular Gentcs - Microbio, College-Medicine
eric.t.wang@ufl.edu
Chenglong Li
Chair Of Medicinal Chemistry and The Nicholas Bodor Professor in Drug Discovery
University of Florida
Ph-Medicinal Chemistry, College-Pharmacy
lic@ufl.edu
Michael Cameron
Senior Scientific Director - Translational Research Institute, Professor - Research, Department Of Molecular Medicine
University of Florida
Sr-Mm-Cameron Lab, Uf Scripps Biomedical Research
michaelcameron@ufl.edu
Samantha Meyer
University of Florida
Sr-Chem-Disney Lab, Uf Scripps Biomedical Research
smeyer1@ufl.edu
Jessica Childs-Disney
Research Assistant Professor
University of Florida
Sr-Chem-Shen Lab, Uf Scripps Biomedical Research
jchildsdisney@ufl.edu
Yanjun Li
Assistant Professor
University of Florida
Ph-Medicinal Chemistry, College-Pharmacy
yanjun.li@ufl.edu
Michalina Janiszewska
Assistant Professor
University of Florida
Sr-Mm-Janiszewska Lab, Uf Scripps Biomedical Research
mjaniszewska@ufl.edu
Amirhossein Taghavi
Postdoctoral Associate, The Disney Lab
University of Florida
Sr-Chem-Disney Lab, Uf Scripps Biomedical Research
a.taghavi@ufl.edu
Expertnet Author Network
Experts within Florida Expertnet that have co-authored works with Matthew Disney.
Ilyas Yildirim
Associate Professor
Florida Atlantic University
Chemistry & Biochemistry, College Of Science
iyildirim@fau.edu
Works Co-Authored: 57
Eric Wang
Professor
University of Florida
Md-Molecular Gentcs - Microbio, College-Medicine
eric.t.wang@ufl.edu
Works Co-Authored: 130
Chenglong Li
Chair Of Medicinal Chemistry and The Nicholas Bodor Professor in Drug Discovery
University of Florida
Ph-Medicinal Chemistry, College-Pharmacy
lic@ufl.edu
Works Co-Authored: 35
Inactive Expert
Lukasz Sznajder
Research Assistant Professor
University of Florida
Md-Molecular Gentcs - Microbio, College-Medicine
Works Co-Authored: 12
Gavin Rumbaugh
Professor
University of Florida
Sr-Neuro-Rumbaugh Lab, Uf Scripps Biomedical Research
gavinrumbaugh@ufl.edu
Works Co-Authored: 88
Inactive Expert
ALEXANDER ADIBEKIAN
Associate Professor
University of Florida
Sr-Chemistry, Uf Scripps Biomedical Research
Works Co-Authored: 63
Donald Phinney
Professor
University of Florida
Sr-Mm-Phinney Lab, Uf Scripps Biomedical Research
dphinney@ufl.edu
Works Co-Authored: 163
Thomas Kodadek
Professor Of Chemistry
University of Florida
Sr-Chem-Kodadek Lab, Uf Scripps Biomedical Research
kodadek@ufl.edu
Works Co-Authored: 447
Ben Shen
Professor
University of Florida
Sr-Chem-Shen Lab, Uf Scripps Biomedical Research
ben.shen@ufl.edu
Works Co-Authored: 389
Michael Cameron
Senior Scientific Director - Translational Research Institute, Professor - Research, Department Of Molecular Medicine
University of Florida
Sr-Mm-Cameron Lab, Uf Scripps Biomedical Research
michaelcameron@ufl.edu
Works Co-Authored: 337
Kendall Nettles
Associate Professor
University of Florida
Sr-Im-Nettles Lab, Uf Scripps Biomedical Research
k.nettles@ufl.edu
Works Co-Authored: 80
Jessica Childs-Disney
Research Assistant Professor
University of Florida
Sr-Chem-Shen Lab, Uf Scripps Biomedical Research
jchildsdisney@ufl.edu
Works Co-Authored: 97
Gogce Crynen
Shared Services Core / Bioinformatics and Statistics Core Director
University of Florida
Sr-Bioinformatics, Uf Scripps Biomedical Research
gogce@ufl.edu
Works Co-Authored: 14
Yanjun Li
Assistant Professor
University of Florida
Ph-Medicinal Chemistry, College-Pharmacy
yanjun.li@ufl.edu
Works Co-Authored: 20
William Ja
Associate Professor Department Of Neuroscience
University of Florida
Sr-Neuro-Ja Lab, Uf Scripps Biomedical Research
w.ja@ufl.edu
Works Co-Authored: 3
Amirhossein Taghavi
Postdoctoral Associate, The Disney Lab
University of Florida
Sr-Chem-Disney Lab, Uf Scripps Biomedical Research
a.taghavi@ufl.edu
Works Co-Authored: 15
Michael Benatar
University of Miami
Neurology, Medical
mbenatar@miami.edu
Works Co-Authored: 536
Joanne Wuu
University of Miami
Neurology, Medical
jwuu@miami.edu
Works Co-Authored: 156
Websites
ORCID 0000-0001-8486-1796
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Search Google Scholar for Matthew Disney
Contact Information
mdisney@ufl.edu
5612282203
130 SCRIPPS WAY A331 # 3A1 JUPITER, FL 33458
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