The Institute for Therapeutic Innovation (ITI) has as a mission and focus of developing optimized chemotherapy for medically important Infectious Diseases. In contradistinction to other laboratories, ITI does not focus upon a specific pathogen, but we apply the same therapeutic principles to many different pathogens. Examples include nosocomial pathogens (Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella species, and MRSA), tuberculosis, Select Agents, Pandemic Influenza, HIV, Hepatitis C, and other bacterial and viral pathogens. We have developed unique and innovative model systems, including the hollow fiber infection model to probe for optimized drug regimens which kill pathogens and suppress resistance emergence. Distinctively, we apply cutting edge mathematical models to these data. This allows rapid identification of optimal regimens. This work is done to provide the best care for seriously infected patients.
DCU Number: 10.2530
