Reginald Frye

Joy MS, Frye RF, Nolin TD, Roberts BV, La MK, Wang J, Brouwer KL, Dooley MA, Falk RJ. In Vivo Alterations in Drug Metabolism and Transport Pathways in Patients with Chronic Kidney Diseases. Pharmacotherapy. 2013 Sep 6. doi: 10.1002/phar.1347. [Epub ahead of print] PubMed PMID: 24038489.

 

Li L, Han AR, Kinghorn AD, Frye RF, Derendorf H, Butterweck V. Pharmacokinetic properties of pure xanthones in comparison to a mangosteen fruit extract in rats. Planta Med. 2013 May;79(8):646-53. doi: 10.1055/s-0032-1328543. Epub 2013 May 14. PubMed PMID: 23673465.

 

Wikoff WR, Frye RF, Zhu H, Gong Y, Boyle S, Churchill E, Cooper-Dehoff RM, Beitelshees AL, Chapman AB, Fiehn O, Johnson JA, Kaddurah-Daouk R; Pharmacometabolomics Research Network. Pharmacometabolomics reveals racial differences in response to atenolol treatment. PLoS One. 2013;8(3):e57639. doi: 10.1371/journal.pone.0057639. Epub 2013 Mar 11. PubMed PMID: 23536766; PubMed Central PMCID: PMC3594230.

 

Joy MS, La M, Wang J, Bridges AS, Hu Y, Hogan SL, Frye RF, Blaisdell J, Goldstein JA, Dooley MA, Brouwer KL, Falk RJ. Cyclophosphamide and 4-hydroxycyclophosphamide pharmacokinetics in patients with glomerulonephritis secondary to lupus and small vessel vasculitis. Br J Clin Pharmacol. 2012 Sep;74(3):445-55. doi: 10.1111/j.1365-2125.2012.04223.x. PubMed PMID: 22380717; PubMed Central PMCID: PMC3477346.

 

Le MT, Frye RF, Rivard CJ, Cheng J, McFann KK, Segal MS, Johnson RJ, Johnson JA. Effects of high-fructose corn syrup and sucrose on the pharmacokinetics of fructose and acute metabolic and hemodynamic responses in healthy subjects. Metabolism. 2012 May;61(5):641-51. doi: 10.1016/j.metabol.2011.09.013. Epub 2011 Dec 5. PubMed PMID: 22152650; PubMed Central PMCID: PMC3306467.

 

Sampath C, Haug K, Thanei S, Hamburger M, Derendorf H, Frye R, Butterweck V. Pharmacokinetics of valerenic acid in rats after intravenous and oral administrations. Planta Med. 2012 Apr;78(6):575-81. doi: 10.1055/s-0031-1298301. Epub 2012 Mar 12. PubMed PMID: 22411722.

 

Ardjomand-Woelkart K, Kollroser M, Magnes C, Sinner F, Frye RF, Derendorf H, Bauer R, Butterweck V. Absolute/relative bioavailability and metabolism of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides (tetraenes) after intravenous and oral single doses to rats. Planta Med. 2011 Nov;77(16):1794-9. doi: 10.1055/s-0030-1271120. Epub 2011 May 20. PubMed PMID: 21604240.

 

Flaherty KT, Lathia C, Frye RF, Schuchter L, Redlinger M, Rosen M, O'Dwyer PJ. Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: a phase I/II pharmacokinetic interaction study. Cancer Chemother Pharmacol. 2011 Nov;68(5):1111-8. doi: 10.1007/s00280-011-1585-0. Epub 2011 Feb 25. PubMed PMID: 21350850.

 

Shin J, Pauly DF, Pacanowski MA, Langaee T, Frye RF, Johnson JA. Effect of cytochrome P450 3A5 genotype on atorvastatin pharmacokinetics and its interaction with clarithromycin. Pharmacotherapy. 2011 Oct;31(10):942-50. doi: 10.1592/phco.31.10.942. PubMed PMID: 21950641; PubMed Central PMCID: PMC3712822.