Malcolm Maden

REINJTJES, S., BLENTIC, A., GALE, E. & MADEN, M. (2005). The control of morphogen signalling: Regulation of the synthesis and catabolism of retinoic acid in the developing embryo. Dev. Biol. 285, 224-237.

WILSON, L. & MADEN, M. (2005). The mechanisms of dorsoventral patterning in the vertebrate neural tube.  Dev. Biol. 282, 1-13.

WONG, L-F, YIP, P.K., BATTAGLIA, A., GRIST, J., CORCORAN, J., MADEN, M., AZZOUZ, M., KINGSMAN, S.M., KINGSMAN, A.J., MAZARAKIS, N.D. & MCMAHON, S.B. (2005). Retinoic acid receptor b2 promotes functional regeneration of sensory axons into the adult rat spinal cord. Nature Neurosci. 9, 243-250  .

MADEN, M. (2006). Retinoids and the spinal cord. J. Neurosci. 66, 726-738.

MADEN M. (2006). Analysis of retinoid signalling in embryos. In Growth Factor Signaling in the Embryos. M.Whitman & A.K.Slater (eds) pp87-128. CRC Press, Boca Raton, Florida.

YIP,P.K., WONG, L-F., PATTINSON, D., BATTAGLIA, A., GRIST, J., BRADBURY, E.J., MADEN, M., MCMAHON, S.B. & MAZARAKIS, N.D. (2006). Lentiviral vector expressing retinoic acid receptor b2 promotes recovery of function after corticospinal injury in the adult rat spinal cord. Human Mol. Genet. 15, 1-12.

MADEN, M. (2006). Retinoids have differing efficacies at inducing alveolar regeneration in a dexamethasone treated mouse model. . Am. J. Resp. Cell Mol Biol. 35, 260-267.

PO, S.L., YIP, P.K., BUNTING, S, WONG, L-F., MAZARAKIS, N.D., HALL, S.,MCMAHON, S., MADEN, M. & CORCORAN, J.P. (2006). Interactions between retinoic acid, nerve growth factor and sonic hedgehog signalling pathways in neurite outgrowth. Dev. Biol. 298, 167-175.

CHAMBERS, D., MADEN, M. & LUMSDEN, A. (2007). Raldh-independent generation of retinoic during vertebrate embryogenesis by Cyp1B1 Development 134, 1369-1383.

REIJNTJES, S., RODAWAY, A. & MADEN, M. (2007). The retinoic acid metabolizing gene, CYP26B1, functions in zebrafish to pattern the cranial neural crest. Int. J. Dev. Biol. 51, 351-360.

MADEN, M. (2007). Commentary.  Respiratory Medicine: COPD Update 3, 71.

MADEN, M., BLENTIC, A., REIJNTJES, S., SEGUIN, S., GALE, E. & GRAHAM, A. (2007). Retinoic acid is required for specification of the ventral eye field and for Rathke’s pouch in the avian embryo. Int. J. Dev. Biol. 51, 191-200.

MADEN, M. (2007). Retinoic acid in the development, regeneration and maintenance of the nervous system. Nature Reviews Neurosci. 8, 755-765.

WILSON, L.J., MYATT, A., SHARMA, A., MADEN, M. and WINGATE, RJT. (2007). Retinoic acid is a potential dorsalising signal in the late embryonic chick hindbrain. BMC Dev. Biol. 7, 138.

STINCHCOMBE, S.V. and MADEN, M. (2008). Retinoic acid-induced alveolar regeneration. Critical differences in strain sensitivity. Am. J. Respir. Cell Mol. Biol. 38, 185-191.

GONCALVES, M.B., AGUDO, M., CONNOR, S., MCMAHON S., MINGER, S.L., MADEN, M. & CORCORAN, J.P. (2009). Sequential RARbeta and alpha signalling in vivo can induce adult forebrain neural progenitor cells to differentiate into neurons through Shh and FGF signalling pathways. Dev. Biol. 326, 305-313.

HIND, M., GILTHORPE, A., STINCHCOMBE, S.V. & MADEN, M. (2009). Retinoid induction of alveolar regeneration: from mice to man? Thorax 64, 451-457.

KRAGL, M., KNAPP, D., NACU, E., KHATTAK, S., MADEN, M., EPPERLEIN, H-H. and TANAKA, E.M. (2009). Cells keep a memory of their tissue origin during axolotl limb regeneration. Nature 460, 60-5.

AGUDO, M., YIP, P., DAVIES, M., BRADBURY, E., DOHERTY, P., MCMAHON, S., MADEN, M. & CORCORAN, J.P. (2010). A retinoic acid receptor beta agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord. Neurobiol. Dis. 37, 147-155.

 XU Q., HENDRY B. M., MADEN M., LU H., WONG  Y. F., RANKIN A. R., NOOR M. & KOPP J. B. (2010). Kidneys of Alb/TGF-ß1 transgenic mice are deficient in retinoic acid and exogenous retinoic acid shows dose-dependent toxicity. Nephron Exp. Nephrol. 114, e127-e132.

REIJNTJES, S., ZILE, M.H. & MADEN, M. (2010). The expression of Stra6 and Rdh10 in the avian embryo and their contribution to the generation of retinoid signatures. Int. J. Dev. Biol. 54, 1267-1275.

JARVIS, C.I., GONCALVES, M.B., CLARKE, E., DORGUEL, M., KALINDJIAN, S.B., THOMAS, S.A., MADEN, M. & CORCORAN, J.P.T. (2010). Retinoic acid receptor-a signalling antagonizes both intracellular and extracellular amyloid-b production and prevents neuronal cell death caused by amyloid-b. Eur. J. Neurosci. 32, 1246-1255.?

HIND, M & MADEN, M. (2011). Is a regenerative approach viable for the treatment of COPD? Br. J. Pharmacol.