Research Terms
1. Fernandez-Funez P, Lu C-H, Rincon-Limas DE, Garcia-Bellido A and Botas J (1998). The relative expression amounts of apterous and its co-factor dLdb/Chip are critical for dorso-ventral compartmentalization in the Drosophila wing. EMBO J., 17, 6846-6853. PMID: 9843490
2. Fernandez-Funez P, Nino-Rosales ML, de Gouyon B, She W-C, Luchak JM, Martinez P, Turiegano E, Benito J, Capovilla M, Skinner PJ, McCall A, Canal I, Orr H, Zoghbi HY and Botas J (2000). Identification of genes that modify ataxin-1-induced neurodegeneration. Nature, 408, 101-106. (Featured in Nat Rev Neurosci. (2000) 1:154). PMID: 11081516.
3. Chen H-K, Fernandez-Funez P, Acevedo SF, Lam YC, Kaytor MD, Fernandez MH, Aitken A, Skoulakis EMC, Orr H, Botas J and Zoghbi HY (2003). Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1. Cell, 113, 457-468. (Picture selected for cover, Featured in Science, 301: 59-60). PMID: 12757707.
4. Martin-Peña A, Acebes A, Rodriguez JR, Sorribes A, de Polavieja GG, Fernandez-Funez P* and Ferrus A (2006). Age-Independent Synaptogenesis by Phosphoinositide 3 Kinase. J. Neuroscience 26: 10199-10208. PMID: 17021175.
5. Branco J, Al-Ramahi I, Ukani L, Perez AM, Fernandez-Funez P, Rincon-Limas D and Botas J. (2008). Comparative Analysis of Genetic Modifiers in Drosophila Points to Common and Mechanisms of Pathogenesis among Polyglutamine Diseases. Hum Mol Genet 17, 376-390. PMID: 17984172
6. Casas-Tinto S, Gomez-Velazquez M, Granadino B and Fernandez-Funez P*. (2008). FoxK mediates TGF-beta signalling during midgut differentiation. J. Cell Biol. 183, 1049-1060.
7. Fernandez-Funez P*, Casas-Tinto S, Zhang Y, Gomez-Velazquez M, Morales-Garza, MA, Cepeda-Nieto AC, Castilla J, Soto C and Rincon-Limas DE. (2009). In Vivo Generation of Neurotoxic Prion Protein Isoforms: Role for Hsp70 in Prion Protein Conversion. PloS Genetics 5, e1000507. PMID: 19503596
8. Fernandez-Funez P*, Zhang Y, Casas-Tinto S, Xiao X, Zou WQ, Rincon-Limas DE. (2010). Sequence-dependent prion protein misfolding and neurotoxicity. J. Biol. Chem., 285 (47): 36897-908. PMID: 20817727.
9. Casas-Tinto S, Zhang Y, Sanchez-Garcia J, Gomez-Velazquez M, Rincon-Limas DE Fernandez-Funez P*. (2011). The ER-stress transcription factor XBP1s prevents Amyloid-ß neurotoxicity. Hum. Mol. Gen. 20 (11): 2144-60. PMID: 21389082.
10. Zou W-Q, Xiao X, YuanJ, Fujioka H, Wang X, Richardson S, Zhou X, Zou R, Li S, Zhu X, McGeer PL, McGeehan J, Kneale G, Rincon-Limas DE, Fernandez-Funez P, Lee H, Petersen RB, Smith MA, and Guo JP. (2011). Amyloid-β42 interacts mainly with insoluble prion protein in the Alzheimer’s brain. J. Biol. Chem. 286 (17): 15095-105. PMID: 21393248
11. Tare M, Modi RM, Nainaparampil JN, Bedi S, Fernandez-Funez P, Kango-Singh M and Singh. (2011). Activation of JNK signaling mediates Amyloid-ß-dependent cell death. PLoS One 6 (9), e24361, Epub Sep 14. PMID: 21949710.
12. Castillo-Carranza DL, Zhang Y, Guerrero-Muñoz MJ, Kayed R, Rincon-Limas DE and Fernandez-Funez P*. (2012). Differential activation of the ER stress factor XBP1 by oligomeric assemblies. Neurochem. Res. 37 (8): 1707-17. PMID: 22528838.
13. Jensen K, Williams C, Sanchez-Garcia J, Khare , Mathur K, Graze RM, Hahn DA, McIntyre LM, Rincon-Limas DE and Fernandez-Funez P*. (2012). Purification of transcripts and metabolites from Drosophila heads. Journal of Visualized Experiments (In Press).
14. Zhang Y, Arcia S, Perez B, Fernandez-Funez P and Rincon-Limas DE. p?TubHA4C, a new versatile vector for constitutive expression in Drosophila. (In Press)
Invited Articles
1. Fernandez-Funez P*, Salinas J, Nino-Rosales L and Rincon-Limas DE (2007). Novel Suppressors of Abeta Neurotoxicity. New Trends in Alzheimer and Parkinson Disorders (Salzburg, Austria, Medimont), p37-41.
2. Rincon-Limas DE, Fernandez-Funez P and Resendez-Perez D. (2009). From Fly Genetics to Human Health. Ciencia UANL (Monterrey, Mexico).
3. Fernandez-Funez P*, Casas-Tinto S and Rincon-Limas DE. (2010). Exploring prion protein biology in flies: genetics and beyond. Prion 4, 1-8. PMID: 20083902.
4. Fernandez-Funez P*, Zhang Y, Casas-Tinto S, Jensen K, Zou WQ and Rincon-Limas DE. (2011). Pulling rabbits to reveal the secrets of the prion protein. Comm. and Integra. Biol. 4 (3), May/June, 262-266. PMID: 21980555
5. Rincon-Limas DE, Jensen K and Fernandez-Funez P*. (2012). Drosophila Models of Proteinopathies: the Little Fly that Could. Curr. Pharm. Design, 18 (8), 1108-22. PMID: 22288402
6. Fernandez-Funez P*, Malaga-Trillo E and Rincon-Limas DE. (2012) Alternative models of prion diseases. In: Zou WQ and Gambetti P (ed) Prions and prion diseases, 1st edn. Springer, New York. (In Press).
7. Fernandez-Funez P* and Rincon-Limas DE. (2013). Contribution of the Drosophila eye to unraveling the basis of neurodegeneration in: Singh A (ed) Molecular genetics of axial patterning, growth and disease in Drosophila eye, 1st edn. Springer, New York. (In Press).