- Gu W, Zhu Q, Gao X, Brown M: Simulation of the progression of intervertebral disc degeneration due to decreased nutrition supply. Spine, in press. (NIHMSID: 617882)
- Gao X and Gu W: A new constitutive model for hydration-dependent mechanical properties in biological soft tissues and hydrogels. Journal of Biomechanics, in press (DOI information: 10.1016/j.jbiomech.2014.06.012). (NIHMSID: 608883)
- Wang C, Gonzales SD, Levene H, Gu WY, Huang C-Y: Energy Metabolism of Intervertebral Disc under Mechanical Loading. Journal of Orthopedic Research, 31:1733-8, 2013. (PMCID: PMC3787952)
- Gámez Sazo RE, Maenaka K, Gu W, Wood PM, Bunge MB: Fabrication of growth factor- and extracellular matrix-loaded, gelatin-based scaffolds and their biocompatibility with Schwann cells and dorsal root ganglia, Biomaterials. 2012 Nov;33(33):8529-39. doi: 10.1016/j.biomaterials.2012.07.028.
- Zhu Q, Jackson A, Gu WY: Cell viability in intervertebral disc under various nutritional and dynamic loading conditions: 3D Finite element analysis, Journal of Biomechanics 45 (2012), pp. 2769-2777. DOI information: 10.1016/j.jbiomech.2012.08.044. (PMCID: PMC3593676)
6. Jackson AR, Yuan T-Y, Huang C-Y, Brown, MD, Gu WY: Nutrient Transport in Human Annulus Fibrosus is Affected by Compressive Strain and Anisotropy, Annals of Biomedical Engineering, 40:2551-8, 2012 (DOI: 10.1007/s10439-012-0606-4). (PMCID: PMC3509223)
- Huang C-Y, Travascio F, Gu WY: Quantitative Analysis of Exogenous IGF-1 Administration of Intervertebral Disc Through Intradiscal Injection, Journal of Biomechanics, 45, pp. 1149-1155, 2012. DOI information: 10.1016/j.jbiomech.2012.02.005. (PMCID: PMC3327785)
8. Jackson AR, Huang C-Y, Brown, MD, Gu WY: 3D Finite Element Analysis of Nutrient Distributions and Cell Viability in The Intervertebral Disc: Effects of Deformation and Degeneration, Journal of Biomechanical Engineering, Volume 133, Issue 9, 091006, 2011. (MCID: PMC3318943)
9. Yuan T-Y, Huang C-Y, Gu WY: Novel Technique for Online Characterization of Cartilaginous Tissue Properties, Journal of Biomechanical Engineering, Volume 133, Issue 9, 094504, 2011. (PMCID: PMC3314334)
10. Jackson AR, Huang CY, Gu WY: Effect of Endplate Calcification and Mechanical Loading on the Distribution of Glucose in Intervertebral Disc: A 3-D Finite Element Study. Computer Methods in Biomechanics and Biomedical Engineering, 14, 2, 195-204, 2011 (PMCID: PMC3086201)
11. Fernando HN, Czamanski J, Yuan T-Y, Gu WY, Huang C-Y: Mechanical Loading Affects the Energy Metabolism of Intervertebral Disc Cells, Journal of Orthopedic Research, 29:1634-41, 2011. (PMCID: PMC3137745)
12. Salvatierra JC, Yuan T-Y, Fernando HN, Castillo A, Gu WY, Cheung HS, Huang C-Y. Difference in Energy Metabolism of Annulus Fibrosus and Nucleus Pulposus Cells of The Intervertebral Disc, Cellular and Molecular Bioengineering, 4:302-310, 2011. (PMCID: PMC3103069)
- Travascio F, Gu WY: Simultaneous measurement of anisotropic solute diffusivity and binding reaction rates in biological tissues by FRAP. Annals of Biomedical Engineering, Vol. 39, pp. 53-65, 2011. (DOI: 10.1007/s10439-010-0138-8). (PMCID: PMC3010316)
14. Jackson AR, Yuan T-Y, Huang C-Y, Gu WY: A conductivity approach to measuring fixed charge density in interverteral disc tissue. Annals of Biomedical Engineering, Vol. 37, No. 12, pp. 2566-2573, 2009 (DOI: 10.1007/s10439-009-9792-0, 2009). (PMCID: PMC2809825)
15. Travascio F, Jackson AR, Brown MD, Gu WY: Relationship between solute transport properties and tissue morphology in human annulus fibrosus. Journal of Orthopaedic Research, Vol. 27, Issue 12, pp. 1625-1630, December 2009 (DOI 10.1002/jor.20927, 2009). (PMCID: PMC2798905)
16. Flagler D, Huang C-Y, Yuan T-Y, Lu Z, Cheung HS, Gu WY: Intracellular flow cytometric measurement of extracellular matrix components in porcine intervertebral disc cells. Cellular and Molecular Bioengineering, Vol. 2, No. 2, pp. 264–273, June 2009. (PMCID: PMC2748431)
17. Jackson AR, Travascio F, Gu, WY: Effect of mechanical loading on electrical conductivity in human intervertebral disc. Journal of Biomechanical Engineering, Vol. 131, pp. 054505/1-5, 2009. (PMCID: PMC2714670)
18. Travascio F, Zhao WZ, Gu WY: Characterization of anisotropic diffusion tensor of solute in tissue by video-FRAP imaging technique. Annals of Biomedical Engineering, 37:813-823, 2009. (PMCID: PMC2714646)
19. Yuan T-Y, Jackson AR, Huang C-Y, Gu WY: Strain-dependent diffusion coefficient of oxygen in bovine annulus fibrosus. Journal of Biomechanical Engineering, Vol. 131, pp. 074503/1-4, 2009. (PMCID: PMC2719819)
20. Jackson AR, Gu WY: Transport properties of cartilaginous tissues. Current Rheumatology Review, 5 (1):40-50, 2009. (PMCID: PMC2748424)
21. Huang C-Y, Gu WY: Effects of mechanical compression on metabolism and distributions of oxygen and lactate in intervertebral disc. Journal of Biomechanics, 41:1184-1196, 2008. (PMCID: PMC2398770)
22. Jackson AR, Yuan T-Y, Huang C-Y, Travascio F, Gu WY: Effect of compression and anisotropy on the diffusion of glucose in annulus fibrosus. Spine, 33:1-7, 2008. (PMCID: PMC2671013)
23. Travascio F, Gu WY: Anisotropic diffusive transport in annulus fibrosus: Experimental determination of the diffusion tensor by FRAP technique. Annals of Biomedical Engineering, 35(10):1739-48, 2007. (PMCID: PMC2671030)
24. Huang C-Y, Yuan T-Y, Jackson AR, Hazbun L, Fraker C, Gu WY: Effects of low glucose concentration on oxygen consumption rates of intervertebral disc cells. Spine, 32:2063-2069, 2007. (PMCID: PMC2679584)
- Huang C-Y, Gu WY: Effects of tension-compression nonlinearity on solute transport in charged hydrated fibrous tissues under dynamic compression. Journal of Biomechanical Engineering, 129:423-9, 2007. (PMCID: PMC2671022)
26. Yao H, Gu WY: Three-dimensional inhomogeneous triphasic finite element analysis of physical signals and solute transport in human intervertebral disc under axial compression. Journal of Biomechanics, 40:2071-2077, 2007. (PMCID: PMC2034274)
27. Yao H, Gu WY: Convection and diffusion of solute in charged hydrated soft tissues: a mixture theory approach. Journal of Biomechanics and Modeling in Mechanobiology, 6:63-72, 2007. (PMCID: PMC2671028)
28. Fraker CA, Alvarez S, Papadopoulos P, Giraldo J, Gu WY, Ricordi C, Inverardi L, Domínguez-Bendala J: Enhanced oxygenation promotes beta cell differentiation in vitro. Stem Cells, 25(12):3155-64, 2007.
29. Yao H, Gu WY: Physical signals and solute transport in human intervertebral disc during compressive stress relaxation: 3D finite element analysis. Biorheology, 43(3-4):323-335, 2006.
30. Jackson A, Yao H, Brown M, Gu WY: Anisotropic ion diffusivity in intervertebral disc: an electrical conductivity approach. Spine, 31:2783-2789, 2006.
31. Mow VC, Gu WY, Chen FH: Structure and Function of Articular Cartilage and Meniscus, in Basic Orthopaedic Biomechanics & Mechano-Biology, ed by VC Mow and R Huiskes, Lippincott Williams and Wilkins, Philadelphia, PA. pp.181-258, 2005.
32. Yao H, Gu WY: Physical signals and solute transport in cartilage under dynamic unconfined compression: Finite element analysis. Annals of Biomedical Engineering, 32:380-390, 2004.
33. Gu WY, Yao H, Vega A, Flagler D: Diffusivity of ions in agarose gels and intervertebral disc: Effect of porosity. Annals of Biomedical Engineering, 32:1710-1717, 2004.
34. Gu WY, Sun DN, Lai WM, Mow VC: Analysis of the dynamic permeation experiment with implication to cartilaginous tissue engineering. J Biomechanical Engineering, 26:485-491, 2004.
35. Gu WY, Yao H: Effects of hydration and fixed charge density on fluid transport in charged hydrated soft tissues. Annals of Biomedical Engineering, 31:1162-1170, 2003.
36. Gu WY, Yao H, Huang CY, Cheung HS: New insight into deformation-dependent hydraulic permeability of gels and cartilage, and dynamic behavior of agarose gels in confined compression. J Biomechanics, 36:593-598, 2003.
37. Gu WY, Justiz MA, Yao H: Electrical conductivity of lumbar annulus fibrosis: Effects of porosity and fixed charge density. Spine, 27:2390-2395, 2002.
38. Gu WY, Justiz MA: Apparatus for measuring the swelling dependent electrical conductivity of charged hydrated soft tissues. J Biomechanical Engineering, 124:790-793, 2002.
39. Yao H,Justiz MA, Flagler D, Gu WY: Effects of Swelling Pressure and Hydraulic Permeability on Dynamic Compressive Behavior of Lumbar Annulus Fibrosus. Annals of Biomedical Engineering, 30:1234-1241, 2002.
40. Gu WY, Lai WM, Mow VC: Transport of multi-electrolytes in charged hydrated biological soft tissues. Transport in Porous Media 34: 143-157, 1999.
41. Sun DN, Gu WY, Guo XE, Lai WM, Mow VC: A mixed finite element formulation of triphasic mechano-electrochemical theory for charged, hydrated biological soft tissues. International Journal for Numerical Methods in Engineering 45:1375-1402, 1999.
42. Gu WY, Mao XG, Foster RJ, Weidenbaum M, Mow VC, Rawlins BA: The anisotropic hydraulic permeability of human lumbar anulus fibrosus: Influence of age, degeneration, direction, and water content. Spine 24:2449-2455, 1999.
43. Gu WY, Mao XG, Rawlins BA, Foster RJ, Iatridis JC, Sun DN, Weidenbaum M, Mow VC: Streaming potential of human lumbar anulus fibrosus is anisotropic and affected by disc degeneration. J Biomechanics 32:1183-1189, 1999.
44. Lai WM, Gu WY, Mow VC: On the conditional equivalence of chemical loading and mechanical loading on articular cartilage. J Biomechanics 31:1181-1185,1998.
45. Gu WY, Lai WM, Mow VC: A mixture theory for charged hydrated soft tissues containing multi-electrolytes: Passive transport and swelling behaviors. J Biomechanical Engineering 120:169-180, 1998.
46. Mow VC, Ateshian GA, Lai WM, Gu WY: Effects of fixed charge density on the stress-relaxation behavior of hydrated soft tissues in a confined compression problem. International Journal of Solids and Structures35:4945-4962, 1998.
47. Gu WY, Lai WM, Mow VC: A triphasic analysis of negative osmotic flow through charged-hydrated soft tissues. J Biomechanics 30:71-78, 1997.
48. Setton LA, Gu WY, Lai WM, Mow VC: Predictions of the swelling-induced pre-stress in articular cartilage. In: Mechanics of Poroelastic Media, ed by APS Selvadurai, Kluwer Academic Publishers, 1995, 299-322.
49. Gu WY, Lai WM, Mow VC: Transport of fluid and ions through a porous-permeable charged-hydrated tissue, and streaming potential data on normal bovine articular cartilage. J Biomechanics 26:709-723, 1993.
50. Gu WY, Lai WM, Mow VC: Theoretical basis for measurements of cartilage fixed-charge density using streaming current and electro-osmosis effects. Advances in Bioengineering, ASME, New York, ed by JM Tarbell, BED26:55-58, 1993.
51. Lai WM, Gu WY, Mow VC: Factors influencing interstitial flow in articular cartilage, Bioengineering Conference, ASME, New York, ed by NA Langrana, et al, BED24:395-398, 1993.
52. Gu WY, Lai WM, Mow VC: Analysis of fluid and ion transport through a porous charged-hydrated biological tissue during a permeation experiment, Proc Symp Comp Mech Porous Material, ed by NJ Salamon and RM Sullivan, AMD-Vol 136, pp 29-41, ASME, 1992.
53. Setton LA, Gu WY, Lai WM, Mow VC: Pre-stress in articular cartilage due to internal swelling pressures. Advances in Bioengineering, ASME, New York, ed by WM Bidez, BED19:485-492, 1992.
54. Gu WY, Lai WM, Mow VC: Hydraulic permeability and electro-kinetic properties of charged-hydrated tissues during permeation. Advances in Bioengineering, ASME, New York, ed by WM Bidez, BED19:593-596, 1992.
55. Lai WM, Gu WY, Setton LA, Mow VC: Constitutive theory for the mechano- electrochemical properties of articular cartilage. Biomech Symp ASME, New York, ed by RL Spilker, MH Friedman, AMD120:133-138, 1991.
56. Lai WM, Gu WY, Setton LA, Mow VC: Conditional equivalence of chemical loading and mechanical loading on articular cartilage. In: Advances in Bioengineering, ASME, New York, ed by R Vanerby, BED18:481-484, 1991.
57. Gu WY, Hou JS, Lai WM, Mow VC: Ion transport through charged hydrated tissues by convection and diffusion. In: Advances in Bioengineering, ASME, New York, ed by SA Goldstein, BED17:219-224, 1990.
