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Arnold Louie
Aso Prg Dir & Prof
MD-INST FOR THERAPEUTIC INNOV | COLLEGE-MEDICINE
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Title
04-2027
Development of CZ-02s (AIIPS), a New Class of Antibacterial for the Treatment of Drug-Resistant Bacterial Infections, including those caused by Multidrug-Resistant Yersinia pestis, Francisella tularensis, and Burkholderia mallei
Development of CZ-02s (AIIPS), a New Class of Antibacterial for the Treatment of Drug-Resistant Bacterial Infections, including those caused by Multidrug-Resistant Yersinia pestis, Francisella tularensis, and Burkholderia mallei
DEFENSE THREAT REDUCTION AGENC
11-2024
Novel Strategies for Antibiotic Combinations to Combat Gram-negative Superbugs
Novel Strategies for Antibiotic Combinations to Combat Gram-negative Superbugs
NATL INST OF HLTH NIAI
11-2024
Novel Strategies for Antibiotic Combinations to Combat Gram-negative Superbugs
Novel Strategies for Antibiotic Combinations to Combat Gram-negative Superbugs
STATE UNIV OF NEW YORK BUFFAL
09-2024
Battelle Subcontract 778380 SAB Year 1
Battelle Subcontract 778380 SAB Year 1
BATTELLE MEMORIAL INS
09-2024
Battelle Subcontract 778380 SAB Year 1
Battelle Subcontract 778380 SAB Year 1
DEFENSE THREAT REDUCTION AGENC
07-2024
Combating resistant superbugs by understanding the molecular determinants of target site penetration and binding
Combating resistant superbugs by understanding the molecular determinants of target site penetration and binding
NATL INST OF HLTH NIAI
10-2023
Next-generation combination dosing strategies to combat resistant Acinetobacter baumannii
Next-generation combination dosing strategies to combat resistant Acinetobacter baumannii
NATL INST OF HLTH NIAI
08-2023
Efficacy of the polypeptide antibiotic SPR206 when administered alone and in combination with beta-lactam partner antibiotics for the killing of multidrug-resistant nosocomial Gram-negative bacterial pathogens and the impact of combination therapy on resi
Efficacy of the polypeptide antibiotic SPR206 when administered alone and in combination with beta-lactam partner antibiotics for the killing of multidrug-resistant nosocomial Gram-negative bacterial pathogens and the impact of combination therapy on resi
SPERO THERAPEUTICS
05-2023
A Mechanism Based Approach to Metallo beta-Lactamase Inhibition
A Mechanism Based Approach to Metallo beta-Lactamase Inhibition
CASE WESTERN RESERVE UNI
05-2023
A Mechanism Based Approach to Metallo beta-Lactamase Inhibition
A Mechanism Based Approach to Metallo beta-Lactamase Inhibition
NATL INST OF HLTH NIAI
08-2022
Pharmacokinetic-Pharmacodynamic Studies to Support Dose Selection for Tebipenem for the Treatment of Mycobacterium avium Complex Pulmonary Disease
Pharmacokinetic-Pharmacodynamic Studies to Support Dose Selection for Tebipenem for the Treatment of Mycobacterium avium Complex Pulmonary Disease
SPERO THERAPEUTICS
07-2022
Optimizing combination therapy for accelerate clinical cure of tuberculosis
Optimizing combination therapy for accelerate clinical cure of tuberculosis
NATL INST OF HLTH NIAI
12-2021
Project Bioshield
Project Bioshield
SPERO THERAPEUTICS
12-2021
A Preclinical Mouse Model of Acinetobacter buamannii Infection For Antibacterial Development
A Preclinical Mouse Model of Acinetobacter buamannii Infection For Antibacterial Development
UNIV OF SOUTHERN CALIFORNI
12-2021
A Preclinical Mouse Model of Acinetobacter buamannii Infection For Antibacterial Development
A Preclinical Mouse Model of Acinetobacter buamannii Infection For Antibacterial Development
US FOOD AND DRUG ADM
10-2021
Ceftazidime/Avibactam plus Aminoglycoside for Ceftazidime/Avibactam Resistant KPC-3 Klebsiella pneumonia
Ceftazidime/Avibactam plus Aminoglycoside for Ceftazidime/Avibactam Resistant KPC-3 Klebsiella pneumonia
ALLERGAN SALE
05-2021
Broad spectrum antibacterials selectively targeting an un-drugged site on the ribosome
Broad spectrum antibacterials selectively targeting an un-drugged site on the ribosome
CURZA
05-2021
Broad spectrum antibacterials selectively targeting an un-drugged site on the ribosome
Broad spectrum antibacterials selectively targeting an un-drugged site on the ribosome
NATL INST OF HLTH NIAI
05-2021
OR-DRPD-ROF2017:Combating resistant Gram-negative bacterial superbugs via omics techniques
OR-DRPD-ROF2017:Combating resistant Gram-negative bacterial superbugs via omics techniques
UF DSR OPPORTUNITY FUN
05-2021
Rapid Identification of Optimal Combination Regimens for Pseudomonas aeruginosa
Rapid Identification of Optimal Combination Regimens for Pseudomonas aeruginosa
NATL INST OF HLTH NIAI
06-2019
CZ-02 pharmacodynamic studies, A New Class of Antibiotics Selectively Inhibiting Bacterial Protein Synthesis
CZ-02 pharmacodynamic studies, A New Class of Antibiotics Selectively Inhibiting Bacterial Protein Synthesis
BIOMEDICAL ADVANCED RES & DEVLPMT AUTHOR
06-2019
CZ-02 pharmacodynamic studies, A New Class of Antibiotics Selectively Inhibiting Bacterial Protein Synthesis
CZ-02 pharmacodynamic studies, A New Class of Antibiotics Selectively Inhibiting Bacterial Protein Synthesis
CURZA
06-2019
Can ceftazidime-avibactam be pharmacodynamically-optimized to prevent emergence of resistance by KPC3-expressing Enterobacteriaceae?
Can ceftazidime-avibactam be pharmacodynamically-optimized to prevent emergence of resistance by KPC3-expressing Enterobacteriaceae?
ALLERGAN SALE
05-2019
Nitroxoline Small Molecules as Cures for Persistent Bacterial Infections
Nitroxoline Small Molecules as Cures for Persistent Bacterial Infections
UF DIV OF SPONSORED RES OPPORTUNITY FUN
05-2019
Nitroxoline Small Molecules as Cures for Persistent Bacterial Infections
Nitroxoline Small Molecules as Cures for Persistent Bacterial Infections
UF DSR OPPORTUNITY FUN
05-2018
Pharmacokinetics-Pharmacodynamics of RG-6080, a Potent Non-Beta-Lactam Beta-Lactamase Inhibitor, In Combination with Meropenem, Piperacillin, and/or Cefepime for the Killing of Multidrug-Resistant Enterobacteriaceae and Pseudomonas aeruginosa in Neutropen
Pharmacokinetics-Pharmacodynamics of RG-6080, a Potent Non-Beta-Lactam Beta-Lactamase Inhibitor, In Combination with Meropenem, Piperacillin, and/or Cefepime for the Killing of Multidrug-Resistant Enterobacteriaceae and Pseudomonas aeruginosa in Neutropen
F Hoffmann La Roche LTD
12-2017
HDTRA114-CBM-06-1-0052 titled GC-072: The First Oral Antibiotic for the Treatment of Acute Melioidosis and Select Agents
HDTRA114-CBM-06-1-0052 titled GC-072: The First Oral Antibiotic for the Treatment of Acute Melioidosis and Select Agents
EMERGENT BIOSOLUTIONS
12-2017
HDTRA114-CBM-06-1-0052 titled GC-072: The First Oral Antibiotic for the Treatment of Acute Melioidosis and Select Agents
HDTRA114-CBM-06-1-0052 titled GC-072: The First Oral Antibiotic for the Treatment of Acute Melioidosis and Select Agents
EVOLVA SA
12-2017
HDTRA114-CBM-06-1-0052 titled GC-072: The First Oral Antibiotic for the Treatment of Acute Melioidosis and Select Agents
HDTRA114-CBM-06-1-0052 titled GC-072: The First Oral Antibiotic for the Treatment of Acute Melioidosis and Select Agents
US DEPT OF DEFENS
10-2017
aIn vitro Hollow Fiber Pharmacodynamic Studies to Identify the Dose nd Frequency of Administration of Iclaprim that Optimizes the Killing of MRSA and Prevents the Emergence of Drug-Resistance During Therapy
aIn vitro Hollow Fiber Pharmacodynamic Studies to Identify the Dose nd Frequency of Administration of Iclaprim that Optimizes the Killing of MRSA and Prevents the Emergence of Drug-Resistance During Therapy
MOTIF BIOSCIENCES INC
09-2017
Dose-fractionation study for AKPN001 (ATCC 43816) for plazomicin and the pharmacokinetics-pharmacodynamics of amikacin
Dose-fractionation study for AKPN001 (ATCC 43816) for plazomicin and the pharmacokinetics-pharmacodynamics of amikacin
ACHAOGEN
09-2017
Dose-fractionation study for AKPN001 (ATCC 43816) for plazomicin and the pharmacokinetics-pharmacodynamics of amikacin
Dose-fractionation study for AKPN001 (ATCC 43816) for plazomicin and the pharmacokinetics-pharmacodynamics of amikacin
BIOMEDICAL ADVANCED RES & DEVLPMT AUTHOR
06-2017
DOSE-RANGE STUDIES FOR PLAZOMICIN IN NEUTROPENIC MURINEPNEUMONIA & THIGH INFECTION MODELS AGAINST CARBAPENEM......
DOSE-RANGE STUDIES FOR PLAZOMICIN IN NEUTROPENIC MURINEPNEUMONIA & THIGH INFECTION MODELS AGAINST CARBAPENEM......
ACHAOGEN
06-2017
DOSE-RANGE STUDIES FOR PLAZOMICIN IN NEUTROPENIC MURINEPNEUMONIA & THIGH INFECTION MODELS AGAINST CARBAPENEM......
DOSE-RANGE STUDIES FOR PLAZOMICIN IN NEUTROPENIC MURINEPNEUMONIA & THIGH INFECTION MODELS AGAINST CARBAPENEM......
US DEPT OF HLTH AND HUMAN SE
05-2017
Optimization of Neoglycoside Antibiotics for Nosocomial Pathogens and SelectAgents
Optimization of Neoglycoside Antibiotics for Nosocomial Pathogens and SelectAgents
NATL INST OF HLTH NIAI
04-2017
Combination Therapy Modeling for M tuberculosis Resistance Suppression and Kill
Combination Therapy Modeling for M tuberculosis Resistance Suppression and Kill
NATL INST OF HLTH NIAI
06-2016
Efficacy of oxazolidinones alone in in vitro EBA studies & in polydrug TB therapy
Efficacy of oxazolidinones alone in in vitro EBA studies & in polydrug TB therapy
MIRIAM HOSPITAL
06-2016
Efficacy of oxazolidinones alone in in vitro EBA studies & in polydrug TB therapy
Efficacy of oxazolidinones alone in in vitro EBA studies & in polydrug TB therapy
NATL INST OF HLTH NIAI
11-2015
Pharmacokinetic study for to determine the comparative s
Pharmacokinetic study for to determine the comparative s
EMERGENT BIOSOLUTIONS
12-2014
Brown University CFAR Supplement
Brown University CFAR Supplement
MIRIAM HOSPITAL
09-2014
Allecra BLI HFS Cefepime/Piperacillin KPC/ESBL Enteroba
Allecra BLI HFS Cefepime/Piperacillin KPC/ESBL Enteroba
ALLECRA THERAPEUTICS
07-2014
Measure the concentration of fosfomycin in mouse plasma.
Measure the concentration of fosfomycin in mouse plasma.
ZAVANTE THERAPEUTICS
12-2013
Resistance Supression for P. Aeruginosa using Novel Comb
Resistance Supression for P. Aeruginosa using Novel Comb
NATL INST OF HLTH NIAI
08-2013
Achaogen BARDA SOW 5
Achaogen BARDA SOW 5
ACHAOGEN
03-2013
Rady Children s Foundation
Rady Children s Foundation
RADY CHILDREN'S HOSP SAN DIEGO
12-2012
Trius NIH NIAID SOW 1
Trius NIH NIAID SOW 1
TRIUS THERAPEUTIC
12-2012
In Vitro Pharmacodynamic Studies for PNU-100480 Alone an
In Vitro Pharmacodynamic Studies for PNU-100480 Alone an
PFIZER IN
12-2012
Cerexa CXLMB39 Avibactam Efficacy Combination HFS
Cerexa CXLMB39 Avibactam Efficacy Combination HFS
CEREXA
06-2012
SOW E Task 2: Achaogen BARDA ACHN-490 Development
SOW E Task 2: Achaogen BARDA ACHN-490 Development
ACHAOGEN
Publications
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Co-Investigator Network
Inactive Expert
Gregory Schultz
Professor
University of Florida
Md-Obgyn-Wound Research Center, College-Medicine
Timothy Garrett
Research Asst Professor
University of Florida
Md-Pathology-Experimental, College-Medicine
tgarrett@ufl.edu
Charles Peloquin
The Jack C. Massey Endowed Professor and Associate Chair Of The Department Pharmacotherapy and Translational Research
University of Florida
Ph-Pharmtherapy Trnsl Rsch, College-Pharmacy
peloquin@ufl.edu
George Drusano
Dir & Prof
University of Florida
Md-Molecular Gentcs - Microbio, College-Medicine
gdrusano@ufl.edu
Ashley Brown
Prg Dir & Aso Prof
University of Florida
Md-Inst For Therapeutic Innov, College-Medicine
ashleybrown@ufl.edu
Charles Heine
Prg Dir & Res Aso Prof
University of Florida
Md-Inst For Therapeutic Innov, College-Medicine
henry.heine@medicine.ufl.edu
Stephan Schmidt
Professor and The Certara Endowed Professor; Director Of The Center For Pharmacometrics and Systems Pharmacology
University of Florida
Ph-Pharmaceutics, College-Pharmacy
sschmidt@cop.ufl.edu
Inactive Expert
Herbert Schweizer
Co Prof
University of Florida
Md-Inst For Therapeutic Innov, College-Medicine
Robert Huigens
Associate Professor
University of Florida
Ph-Medicinal Chemistry, College-Pharmacy
rwhuigens@ufl.edu
Jurgen Bulitta
Professor and The Perry E. Foote Eminent Scholar Chair
University of Florida
Ph-Pharmtherapy Trnsl Rsch, College-Pharmacy
jbulitta@ufl.edu
Kari Basso
Director Mass Spectrometry Research and Education Center
University of Florida
Chemistry, College Of Liberal Arts and Science
kari.basso@chem.ufl.edu
Bret Purcell
Res Aso Prof
University of Florida
Md-Inst For Therapeutic Innov, College-Medicine
bret.purcell@medicine.ufl.edu
Expertnet Author Network
Experts within Florida Expertnet that have co-authored works with Arnold Louie.
Alicja Copik
University of Central Florida
Burnett School Of Biomedical Sciences - Research, College Of Medicine
Alicja.Copik@ucf.edu
Works Co-Authored: 78
Inactive Expert
Hartmut Derendorf
Distinguished Professor Emeritus (Deceased)
University of Florida
Ph-Office Of The Dean, College-Pharmacy
Works Co-Authored: 121
Kenneth Rand
Professor Of Medicine; Medical Director Of Clinical Microbiology Laboratory
University of Florida
Md-Infectious Diseases, College-Medicine
kenrand@pathology.ufl.edu
Works Co-Authored: 54
Charles Peloquin
The Jack C. Massey Endowed Professor and Associate Chair Of The Department Pharmacotherapy and Translational Research
University of Florida
Ph-Pharmtherapy Trnsl Rsch, College-Pharmacy
peloquin@ufl.edu
Works Co-Authored: 105
Hassan Alnuaimat
Professor Of Medicine
University of Florida
Md-Pulmonary Medicine, College-Medicine
hassan1@ufl.edu
Works Co-Authored: 98
George Drusano
Dir & Prof
University of Florida
Md-Molecular Gentcs - Microbio, College-Medicine
gdrusano@ufl.edu
Works Co-Authored: 439
Ashley Brown
Prg Dir & Aso Prof
University of Florida
Md-Inst For Therapeutic Innov, College-Medicine
ashleybrown@ufl.edu
Works Co-Authored: 66
Charles Heine
Prg Dir & Res Aso Prof
University of Florida
Md-Inst For Therapeutic Innov, College-Medicine
henry.heine@medicine.ufl.edu
Works Co-Authored: 68
Inactive Expert
Gregory Hurteau
University of Florida
Md-Inst For Therapeutic Innov, College-Medicine
Works Co-Authored: 1
Inactive Expert
David Brown
University of Florida
Md-Inst For Therapeutic Innov, College-Medicine
Works Co-Authored: 28
Stephan Schmidt
Professor and The Certara Endowed Professor; Director Of The Center For Pharmacometrics and Systems Pharmacology
University of Florida
Ph-Pharmaceutics, College-Pharmacy
sschmidt@cop.ufl.edu
Works Co-Authored: 211
Inactive Expert
Herbert Schweizer
Co Prof
University of Florida
Md-Inst For Therapeutic Innov, College-Medicine
Works Co-Authored: 23
Jurgen Bulitta
Professor and The Perry E. Foote Eminent Scholar Chair
University of Florida
Ph-Pharmtherapy Trnsl Rsch, College-Pharmacy
jbulitta@ufl.edu
Works Co-Authored: 222
Kari Basso
Director Mass Spectrometry Research and Education Center
University of Florida
Chemistry, College Of Liberal Arts and Science
kari.basso@chem.ufl.edu
Works Co-Authored: 32
Awewura Kwara
Professor Of Medicine, Va Section Chief
University of Florida
Md-Infectious Diseases, College-Medicine
awewura.kwara@medicine.ufl.edu
Works Co-Authored: 108
Michael Norris
AfFL Ast Prof
University of Florida
Re-Emerging Pathogens, Uf Research
mhnorris@ufl.edu
Works Co-Authored: 94
Sarah Kim
Assistant Professor
University of Florida
Ph-Pharmaceutics, College-Pharmacy
sarahkim@cop.ufl.edu
Works Co-Authored: 184
Eunjeong Shin
Co Ast Prof
University of Florida
Ph-Pharmtherapy Trnsl Rsch, College-Pharmacy
eshin@ufl.edu
Works Co-Authored: 10
Yinzhi Lang
Research Assistant Professor
University of Florida
Ph-Pharmtherapy Trnsl Rsch, College-Pharmacy
y.lang@ufl.edu
Works Co-Authored: 25
Inactive Expert
Alaa Sayed
Research Assistant Professor
University of Florida
Ph-Pharmtherapy Trnsl Rsch, College-Pharmacy
Works Co-Authored: 5
Inactive Expert
Max Salfinger
Professor
University of South Florida
Works Co-Authored: 7
Websites
ORCID 0000-0001-6227-7580
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alouie@ufl.edu
4073137061
6550 SANGER RD ORLANDO, FL 32827-7445
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