Expert Profile

Share QR code Edit Profile

Xingmin Sun

Assoc Professor

MOLECULAR MEDICINE | MORSANI COLLEGE OF MEDICINE

View:

Select
All (all in one) Research Terms and Keywords Background Publications Activities Speaker Information Technologies Websites Contact

All
Research
Background
Publications
Activities
Speaker
Technologies
Websites
Contact

Research Terms & Keywords

Research Terms

Life Sciences Natural Sciences

Keywords

Antibiotic Resistance Bacterial Pathogenesis Bacterial Toxin Clostridium Difficile Immunology Microbiology Microbiome Analysis Vaccine

Research Projects

Ends

Title

03-2025

Assessment of the efficacies of RVAC¿s mRNAs in mouse an Assessment of the efficacies of RVAC¿s mRNAs in mouse an

08-2023

Effect of bile salt hydrolase inhibitors on Clostridium Effect of bile salt hydrolase inhibitors on Clostridium

05-2022

Multivalent Vaccines Against Clostridium Difficile Infec Multivalent Vaccines Against Clostridium Difficile Infec

08-2018

The Role of Tumor Progression Locus 2 (TPL2) in the Path The Role of Tumor Progression Locus 2 (TPL2) in the Path

03-2017

Multivalent Bacillus mucosal vaccines against Clostridri Multivalent Bacillus mucosal vaccines against Clostridri

03-2017

Signaling pathway of TNF production and Clostridium diff Signaling pathway of TNF production and Clostridium diff

Degrees

PhD, Natural Sciences

University of Kiel, Germany ▪ 2002
MS, Microbiology & Immunology

Nanjing Agricutural University, China ▪ 1994

Awards & Honors

Nominee by the Chair and the Dean for “2018 Excellence in Innovation Award”

University of South Florida ▪ 2018
Nominee by the Chair and the Dean for “2018 Faculty Outstanding Research Achievement Award

University of South Florida ▪ 2018
Tufts Institute for Innovation Inaugural Award

Tufts University ▪ 2014
NIH/NIDDK K01 Mentored Research Scientist Development Award

NIH ▪ 2012
ESCMID (European Society of Clinical Microbiology and Infectious Diseases) Award for the "6th ClostPath International Conference"

European Society of Clinical Microbiology and Infectious Diseases ▪ 2009
Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) Infectious Diseases Fellows Grant, 48th Annual ICAAC/46th IDSA Annual Meeting in Washington, DC

American Society for Microbiology and the Infectious Diseases Society of America ▪ 2008
Postdoctoral Travel Award

American Society for Biochemistry and Molecular Biology ▪ 2007
Young Scientist Award

Federation of European Microbiological Societies for the 7th Symposium on Lactic Acid Bacteria ▪ 2002
Excellent Graduate Student Award

Nanjing Agricultural University, China ▪ 1993
Excellent Graduate Student Award

Nanjing Agricultural University. China ▪ 1992

Publications

Search Google Scholar for Xingmin Sun

Memberships

Anaerobe Society of the Americas, Member; 2016 - present

Society for Mucosal Immunoloogy, Member; 2014 - present

America Society for Microbiology, Member; 2005 - present

Presentations

Clostridium difficile infection: Understanding the host cell response, antibiotic resistance and designing novel approaches to blocking infection

Introduction to Clostridium difficile pathogenesis and development of therapeutics against C difficile infection.

Subject Areas:

Medical Sciences Natural Sciences

Keywords:

Antibiotic Resistance Clostridium Difficile, Pathogenesis Vaccine Development

Audience:

Adults

Duration:

1 hour or less

Fee:

No Cost

updates on Clostridium difficile vaccine

USF Health microbiologist Dr. Xingmin Sun shared team's progress on vaccine for C. diff infection

Subject Areas:

Life Sciences Medical Sciences

Keywords:

Clostridium Difficile, Vaccine Development

Audience:

Adults

Duration:

1 hour or less

Fee:

No Cost

Videos

Anthony Gagliardi Foundation donates $15,000 to Clostridium difficile research at USF HealthType your paragraph here.

Link Address:	https://hscweb3.hsc.usf.edu/giving/2018/10/26/anthony-gagliardi-foundation-donates-15000-to-c-diff-research-at-usf-health/
Source:	upload

14 USF Faculty Recognized in 2018 Outstanding Research Achievement Awards

Link Address:	http://www.research.usf.edu/absolute-news/templates/usfri-template.aspx?articleid=7255&zoneid=1
Source:	upload

Five USF Faculty Members Recognized with Excellence in Innovation Awards

Year:	2019
Link Address:	https://www.usf.edu/news/2020/five-faculty-members-recognized-with-excellence-in-innovation-awards.aspx
Source:	upload

Clostridium difficile vaccine development

Year:	2018
Link Address:	https://hscweb3.hsc.usf.edu/blog/2018/06/13/usf-health-microbiologist-shares-teams-progress-on-vaccine-for-c-diff-infection/
Source:	upload
Duration:	10 minutes

Clostridium difficile pathogenesis and development of therapeutics against C. difficile infection at the University of South Florida

Link Address:	http://www.sunlab-usf.com/
Keywords:	Clostridium difficile
Source:	upload

A Vaccine for Clostridium difficile: What to Consider

Year:	2018
Link Address:	https://hscweb3.hsc.usf.edu/blog/2018/06/13/usf-health-microbiologist-shares-teams-progress-on-vaccine-for-c-diff-infection/
Keywords:	Clostridium difficile, vaccine
Source:	upload
Duration:	3 minutes

A Vaccine for Clostridium difficile: Current Progress

Year:	2018
Link Address:	https://hscweb3.hsc.usf.edu/blog/2018/06/13/usf-health-microbiologist-shares-teams-progress-on-vaccine-for-c-diff-infection/
Keywords:	Clostridium difficile, vaccine
Source:	upload
Duration:	10 minutes

Technologies

Immunogenic Proteins against Clostridium difficile

Described are immunogenic proteins against Clostridium difficile. Also described are compositions comprising the immunogenic proteins. Further described are methods of preventing or treating a Clostridium difficile infection in a subject in need thereof.Pharmaceuticals

Non-toxigenic Clostridium Difficile Spores For Use In Oral Vaccination

Competitive Advantages: Targets main virulent factors, Reduces distribution of toxigenic spores, Improved efficacy, No need for cold storage. Described are non-toxigenic Clostridium difficile strains and spores. Also described are vaccines comprising the Clostridium difficile spores. Further described are methods of preventing or treating a Clostridium difficile infection in a subject in need thereof.USF researchers have designed an oral vaccine to protect users against C. difficile infection. This vaccine uses non-toxigenic C. difficile (NTCD) strains to carry non-pathogenic toxin fragments. These strains will not harm the user and do not cause vaccine associated disease. These live vaccines (NTCD_138, NTCD_169) can target both C. difficile toxins and C. difficile colonization. This will inhibit the main virulence factors of the pathogen and reduce distribution of the spores. Furthermore, the NTCD strains can be converted into a spore form, which can be used as an oral immunogen. The spore form is ideal because spores are resistant to harsh conditions and do not require cold storage, lowering storage expenses. This novel vaccine has the potential to significantly improve current prevention and treatment methods for C. difficile infection.

Websites

Search Google Scholar for Xingmin Sun

twitter

Contact Information

sun5@usf.edu

(813) 974-2011

University of South Florida
4202 E. Fowler Avenue
Tampa, FL 33620

Profile QR code

What is this?