Research Terms
Cellular Physiology Exercise Physiology
Keywords
Aging Cachexia Exercise Physiology Mitochondria Muscle Atrophy Neuromuscular Junction Sarcopenia Skeletal Muscle
Industries
S. Spendiff, M. Vuda, S. Aare, T. Gove, G. Gouspillou, S. Kapchinsky, J. Morais, C. Pilon, M. Aubertin-Leuhedre, S. Hettwer, T. Taivassalo and R.T. Hepple. Denervation Drives Mitochondrial Dysfunction in Skeletal Muscle of Octogenarians. The Journal of Physiology 594.24: 7361-7379, 2016. PMID: 27619626
S. Aare, S. Spendiff, M. Vuda, D. Elkrief, A. Perez, Q.Wu, D. Mayaki, S.N. Hussain, S. Hettwer, and R.T. Hepple. Failed Reinnervation in Aging Skeletal Muscle. Skeletal Muscle Sept. 1; 6(1): 29, 2016. PMID: 27588166
Y. Konokhova, S. Spendiff, N. MacMillan, S. Kapchinsky, C. Pilon, M. Aubertin-Leuhedre, J. Morais, R.T. Jagoe, R.T. Hepple, and T. Taivassalo. Failed upregulation of TFAM protein and mtDNA copy number in oxidatively deficient single fibers of chronic obstructive pulmonary disease locomotor muscle. Skeletal Muscle 18[6]: 10, 2016. PMID: 26893822
G. Gouspillou, C. Scheede-Bergdahl, S. Spendiff, F.M. Purves-Smith, B. Meehan, H. Mlynarski, E. Archer-Lahlou, N. Sgarioto, J. Rak, T. Taivassalo, R.T. Hepple*, and R.T. Jagoe*. Severe Mitochondrial Dysfunction Persists Two Months Following Chemotherapy in Mouse Skeletal Muscle. *Dual senior author. Scientific Reports 5: 8717, 2015. PMID: 25732599
F.M. Purves-Smith, N.M. Solbak, S.L. Rowan, and R.T. Hepple. Severe Atrophy of Slow Fibers in Aging Muscle is Concealed by MHC Co-expression. Experimental Gerontology 47(12): 913-918, 2012. PMID: 22884852
S.L. Rowan, K.A. Rygiel, F.M. Purves-Smith, N.M. Solbak, D.M. Turnbull and R.T. Hepple. Denervation Causes Fiber Atrophy and Myosin Heavy Chain Co-expression in Senescent Skeletal Muscle. PLoS One 7(1): e29082, 2012. PMID: 22235261
M. Picard, T. Taivassalo, D. Ritchie, K.J. Wright, M.M. Thomas, C. Romestaing, and R.T. Hepple. Mitochondrial Structure and Function are Disrupted by Standard Isolation Methods. PLoS One 6(3): e18317, 2011. PMID: 21512578