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Ashish Sharma

Professor With Tenure

MD-SURGERY-VASCULAR | COLLEGE-MEDICINE

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Research
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Activities
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Research Terms & Keywords

Research Terms

Surgery

Keywords

Aortic Aneurysms Lung Transplantation Stem Cell Biology Vascular Biology

Industries

Health Care

Research Projects

Ends

Title

11-2025

Lung IDO-1+ TNFR2+ cDC2 subset in control of lung mucosal tolerance: Mechanism and Application Lung IDO-1+ TNFR2+ cDC2 subset in control of lung mucosal tolerance: Mechanism and Application

NATL INST OF HLTH NHLB

06-2025

Novel specialized pro-resolving lipid mediators in resolution of aortic aneurysms and rupture Novel specialized pro-resolving lipid mediators in resolution of aortic aneurysms and rupture

NATL INST OF HLTH NHLB

12-2023

Novel biomarkers for alpha 1-antitrypsin mediated liver disease in circulating exosomes Novel biomarkers for alpha 1-antitrypsin mediated liver disease in circulating exosomes

ALPHA ONE FO

11-2023

Role of myeloid-derived suppressor cells in aortic aneurysms and rupture Role of myeloid-derived suppressor cells in aortic aneurysms and rupture

FL DEPT OF HLTH BIOMED RES PGM/J&E KIN

06-2023

Pannexin-1 signaling in abdominal aortic aneurysms Pannexin-1 signaling in abdominal aortic aneurysms

NATL INST OF HLTH NHLB

08-2022

Raab Fund - Research Project Raab Fund - Research Project

UF FO

07-2020

Role of Neutrophil Extracellular Traps in AAA Pathogenesis Role of Neutrophil Extracellular Traps in AAA Pathogenesis

NATL INST OF HLTH NHLB

06-2020

Gender Differences in Experimental Aortic Aneurysms Gender Differences in Experimental Aortic Aneurysms

NATL INST OF HLTH NHLB

12-2018

Protective role of stem cell-derived microvesicles and microRNAs in aortic aneurysms Protective role of stem cell-derived microvesicles and microRNAs in aortic aneurysms

AMER HEART ASSOCIATIO

Degrees

PhD, Molecular Physiology & Immunology

University of Virginia ▪ 2012
MBBS, Medicine

MR Medical College, Gulbarga, India ▪ 1998

Awards & Honors

Dean's Excellence in Team Science Research Award

University of Virginia ▪ 2017
Conrad Jobst Award for outstanding contributions in vascular research

Coller Surgical Society, University of Michigan ▪ 2016
Top Ten Abstract Award

American Heart Association ▪ 2015
Peripheral Vascular Disease Council Award

Arteriosclerosis, Thrombosis and Vascular Biology ▪ 2014

Publications

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1) Increasing circulating sphingosine-1-phosphate attenuates lung injury during ex vivo lung perfusion. Mehaffey JH, Charles EJ, Narahari AK, Schubert S, Zhao Y, Laubach VE, Roeser ME, Lynch KR, Kron IL, Sharma AK.; J. Thorac. Cardio. Surg.; Aug;156(2):910-917

2) Invited Commentary. Sharma AK and Upchurch, GR, Jr. J Vasc. Surg. 2018; In Press.

3) Pannexin-1 channel inhibition on endothelial cells mitigates lung ischemia-reperfusion injury. Sharma AK, Charles E, Zhao Y, Narahari AK, Bayliss DA, Kron IL, Ravichandran KS, Isakson B and Laubach VE. American Journal of Physiology (Lung); Aug 1;315(2):L301-L312.

4) Human mesenchymal stem cell-derived extracellular vesicles attenuate aortic aneurysm formation and smooth muscle activation via microRNA-147. Lu G, Salmon MD, Gehrau R, Su G, Smith JR, Weiss ML, Mas VR, Upchurch GR, Jr., Sharma AK. FASEB; In Press; doi: 10.1096/fj.201701138RR.

5) Tamsulosin attenuates abdominal aortic growth. Montgomery WG, Spinosa MD, Cullen JM, Salmon M, Su G, Hassinger T, Sharma AK, Lu G, Fashandi A, Ailawadi G and Upchurch Gr, Jr. Surgery; In Press.

6) Can lung transplant surgeons still be scientists? High productivity despite competitive funding. Narahari AK, Charles EJ, Mehaffey JH, Hawkins RB, Sharma AK, Laubach VE, Tribble CG, Kron IL. The Heart Surgery Forum; In Press.

7) ZFP148 binds with NF-1 to inhibit Smooth Muscle Marker genes Expression and Activates p21 and BAK promoters during Abdominal Aortic Aneurysm Formation. Salmon M, Schaheen B, Pope N, Davis J, Johnston W, Sharma AK, Owens GK, Merchant J, Zehner Z, Upchurch GR, Ailawadi G. Arterio, Thromb. Vascul. Biol.; In Press.

8) A novel swine model of abdominal aortic aneurysm. Cullen MJ, Lu G, Shannon A, Su G, Sharma AK, Salmon MD, Montgomery WG, Johnston W, Ailawadi G, Upchurch GR. J Vascular Surgery; In Press.