Expert Profile

Zhiyong Cheng

Assistant Professor

AG-FOOD SCIENCE - HUMAN NUTR | COLLEGE- AGRICUL - NAT RES

Research Terms & Keywords

Research Terms

Foods and Food Science

Keywords

Adipose Tissue Autophagy Cell Biology Cell Metabolism Epigenetics Metabolic Syndrome Mitochondria Molecular Metabolism Obesity Type 2 Diabetes

Industries

Biotech

Research Projects

Ends

Title

08-2023

Gain in Research Ability Test (GRAT) for a Twofold Backward Design of Lab Courses Multi-Institution Innovative Teaching Award Gain in Research Ability Test (GRAT) for a Twofold Backward Design of Lab Courses Multi-Institution Innovative Teaching Award

06-2023

Examining FoxO1 as a novel target for browning of white adipose tissue Examining FoxO1 as a novel target for browning of white adipose tissue

Publications

Cheng Z. The FoxO-Autophagy Axis in Health and Disease. Trends in Endocrinology & Metabolism, 2019, 30 (9): 658-671.
Tao Z, Liu L, Zheng LD, Cheng Z. Autophagy in Adipocyte Differentiation. Methods in Molecular Biology,2019, 1854:45-53.
Luo J, Wang A, Zhen W, Wang Y, Si H, Jia Z, Alkhalidy H, Cheng Z, Gilbert E, Xu B, Liu D. Phytonutrient genistein is a survival factor for pancreatic β-cells via GPR30-mediated mechanism. Journal of Nutritional Biochemistry, 2018, 58: 59-70.
Shi H, Munk A, Nielsen TS, Daughtry MR, Larsson L, Li S, Høyer KF, Geisler HW, Sulek K, Kjøbsted R, Fisher T, Andersen MM, Shen Z, Hansen UK, England EM, Cheng Z, Højlund K, Wojtaszewski JFP, Yang X, Hulver MW, Helm RF, Treebak JT, Gerrard DE. Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity. Molecular Metabolism, 2018, 11: 160-177.
Tao Z, Zheng LD, Smith C, Luo J, Robinson A, Almeida FA, Wang Z, Olumi AF, Liu D, Cheng Z. Estradiol signaling mediates gender difference in visceral adiposity via autophagy. Cell Death & Disease, 2018, 9: 309.
Cheng Z, Zheng L, Almeida FA. Epigenetic reprogramming in metabolic disorders: nutritional factors and beyond. Journal of Nutritional Biochemistry, 2018, 54: 1-10.
Liu L, Zheng LD, Donnelly SR, Emont MP, Wu J, Cheng Z. Isolation of Mouse Stromal Vascular Cells for Monolayer Culture. Methods in Molecular Biology, 2017, 1566: 9-16.
Liu L, Tao Z, Zheng LD, Brooke JP, Smith CM, Liu D, Long YC, Cheng Z. FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes. Cell Death & Discovery, 2016, 2: 16066.
Wang A, Luo J, Moore W, Alkhalidy H, Wu L, Zhang J, Zhen W, Wang Y, Clegg DJ, Bin Xu, Cheng Z, McMillan RP, Hulver MW, Liu D. GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro. Scientific Report, 2016, 6: 34302.
Liu L, Zheng LD, Zou P, Brooke J, Smith C, Long YC, Almeida FA, Liu D, Cheng Z. FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytes. Cell Cycle, 2016, 15(15): 2033-41.
Cheng Z. FoxO1: mute for a tuned metabolism? Trends in Endocrinology & Metabolism, 2015, 26(8):402-403.
Zheng LD, Linarelli LE, Liu L, Wall SS, Greenawald MH, Seidel RW, Estabrooks PA, Almeida FA, Cheng Z. Insulin resistance is associated with epigenetic and genetic regulation of mitochondrial DNA in obese humans. Clin Epigenetics, 2015, 7(1):60.
Liu L, Zou P, Zheng L, Linarelli LE, Amarell S, Passaro A, Liu D, Cheng Z. Tamoxifen reduces fat mass by boosting reactive oxygen species. Cell Death & Disease,2015, 6:e1586
Zou P, Liu L, Zheng L, Liu L, Stoneman RE, Cho A, Emery A, Gilbert ER, Cheng Z. Targeting FoxO1 with AS1842856 Suppresses Adipogenesis. Cell Cycle,2014;13(23):3759-67
Cheng Z, Schmelz EM, Liu D, Hulver MW. Targeting mitochondrial alterations to prevent type 2 diabetes—Evidence from studies of dietary redox-active compounds. Molecular Nutrition & Food Research, 2014, 58(8):1739-49.
Cheng Z, Almeida FA. Mitochondrial alteration in type 2 diabetes and obesity: An epigenetic link. Cell Cycle, 2014, 13(6):890-7.
Cheng Z, Ristow M. Mitochondria and metabolic homeostasis. Antioxidants & Redox Signaling, 2013, 19(3):240-2.
Wang Z, Cheng Z, Cristofaro V, Li J, Xiao X, Gomez P, Ge R, Gong E, Strle K, Sullivan MP, Adam RM, White MF, Olumi AF. Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes. Diabetes, 2012, 61(8):2134-45.
Cheng Z, White MF. kNOXing on the door of selective insulin resistance. Arteriosclerosis Thrombosis and Vascular Biology, 2012, 32(5):1063-5.
Cheng Z, White MF. The AKTion in non-canonical insulin signaling. Nature Medicine, 2012, 18(3):351-3.
Sadagurski M, Cheng Z, Rozzo A, Palazzolo I, Kelley GR, Dong X, Krainc D, White MF. IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease. Journal of Clinical Investigation, 2011, 121(10):4070-81.
Cheng Z, Zhang J, Ballou DP, Williams CH. Reactivity of thioredoxin as a protein thiol-disulfide oxidoreductase. Chemical Reviews, 2011, 111(9):5768-83.
Long YC, Cheng Z, Copps KD, White MF. Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways.Molecular Cellular Biology, 2011, 31(3):430-41.
Cheng Z, White MF. Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models. Antioxidants & Redox Signaling, 2011, 14(4):649-61.
Cheng Z, Tseng Y, White MF. Insulin signaling meets mitochondria in metabolism. Trends in Endocrinology and Metabolism, 2010, 21(10):589-98.
Cheng Z, White MF. Foxo1 in hepatic lipid metabolism. Cell Cycle, 2010, 9(2):219-20.
Cheng Z, Guo S, Copps K, Dong X, Kollipara R, Rodgers JT, Depinho RA, Puigserver P, White MF. Foxo1 integrates insulin signaling with mitochondrial function in the liver. Nature Medicine, 2009, 15(11):1307-11.

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Presentations

Understanding Obesity and Type 2 Diabetes

Obesity and type 2 diabetes worldwide affect 70% population in the U.S. This presentation will present an updated view of how dietary factors may contribute to obesity and type 2 diabetes. Keeping up with the research finding may inform practical lifestyle modification to prevent the diseases.

Subject Areas:

Education Foods and Food Science Life Sciences Medical Sciences

Keywords:

Diabetes Diet Insulin Function Lifestyle Obesity

Audience:

High School

Duration:

1 hour or less

Fee:

No Cost

Are We what Our Parents Ate?

Diet interacts with genes and alter metabolic activities in ourselves and the offspring. This presentation will discuss how dietary factors regulate genes and affect metabolic health. The potential of lifestyle modification in curbing metabolic disease will also be discussed.

Subject Areas:

Education Foods and Food Science Life Sciences Medical Sciences

Keywords:

Diabetes Epigenetics Lifestyle Metabolism Obesity

Audience:

High School

Duration:

1 hour or less

Fee:

No Cost

Expertnet Author Network

Experts within Florida Expertnet that have co-authored works with Zhiyong Cheng.

Websites

ORCID 0000-0001-7615-9788 OpenAlex Works Search Search Google Scholar for Zhiyong Cheng

Contact Information

z.cheng@ufl.edu

3522943728

572 NEWELL DR
GAINESVILLE, FL 32611-1907

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Zhiyong Cheng

Assistant Professor

AG-FOOD SCIENCE - HUMAN NUTR | COLLEGE- AGRICUL - NAT RES

Research Terms & Keywords

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Presentations

Expertnet Author Network

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