Abstract
Plant derived
compounds are known to exhibit a range of pharmaceutical and biological
activities. There are currently more than two dozen antiretroviral drugs used
for the treatment of HIV, and these drugs are divided into one of six classes
depending on how they attack the virus. The anti-retroviral drugs are usually
combined into three-drug cocktails called highly active antiretroviral therapy
or HAART. While the above-mentioned drugs can dramatically slow the disease's
progress if the patients strictly adhere to the treatment, they still cannot
effectively treat AIDS.FIU inventors
have developed methods to inhibit HIV-1 p24 antigen and therefore treat HIV/AIDS
with a composition comprising extract of Rubia cordifolia. The composition consists
of a hydro-ethanolic extract of Rubia cordifolia. The hydro-ethanolic extract is
obtained from the roots of a Rubia cordifolia plant and has demonstrated
anti-HIV activity.
Benefit
· Significantly suppresses p24 antigen production indicating inhibition of HIV-1 · Significantly suppresses HIV-TLR gene expression in a dose dependent manner · Shows low toxicity to human cells
Market Application
Inhibition of HIV-1 p24 antigen Treatment of HIV/AIDS
Brochure
