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Monoclonal Antibody against Connective Tissue Growth Factor

Belongs to the CTGF/Cyr61/Cef10/NOVH Protein Family

Connective Tissue Growth Factor (CTGF) belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF (Connective Tissue Growth factor) is a cysteine-rich, matrix-associated, heparin-binding protein. In vitro, CTGF mirrors some of the effects of TGF-beta on skin fibroblasts, such as stimulation of extracellular matrix production, chemotaxis, proliferation and integrin expression. CTGF can promote endothelial cell growth, migration, adhesion and survival and is implicated in endothelial cell function and angiogenesis.

Research Terms: Life Sciences > Biology > Cell Biology
Technology > Research Tools
Keywords: Antibody, CTGF, Elisa, Immunochemistry, Monoclonal, reagent,;
Technology Inventors: John Azeke
Daniel Gibson
Priscilla Phillips
Paulette Robinson
Edith Sampson
Gregory Schultz
Technology Information URL:
University: University of Florida
Tech Transfer URL:

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