Abstract
The University of Central Florida invention is a novel two-step, makerspace-based microfabrication strategy for creating high-throughput (HT), self-insulated 3D microelectrode arrays (MEAs). Microstereolithography (µSLA)-based 3D printing technology not only allows for the realization of 3D microelectrode geometries but also enables the monolithic integration of all components of the “bio plate” (standard culture wells) to realize the HT, American National Standards Institute (ANSI)/Society for Lab Automation and Screening (SLAS)-compatible geometry in 1 to 768 well (or more wells) configurations. This approach enables a rapid, accurate, cost-effective, two-step scaling up technique to microfabricate HT-3D microelectrode arrays in several multiwell designs compatible with standard HT assay equipment such as plate readers, robotic handlers, and electrophysiological systems.
Publications
Development of a 3D Printed, Self-Insulated, High-Throughput 3D Microelectrode Array (HT-3DMEA), Journal of Microelectromechanical Systems, vol. 29, no. 5, pp. 1091-1093, Oct. 2020, doi: 10.1109/JMEMS.2020.3003644.
Brochure
