Abstract
FIU inventors have proposed an improvement to the laborious and time-consuming process of the Comet assay. By incorporating automation the slide-filled racks no longer need to be moved from one staining dish to another; the racks remain in one staining container to which buffers and reagents are added and then drained after the required step time. This process includes a tank designed to accommodate two slide racks to undergo electrophoresis. Through this approach, the electrophoresis process is automated and the user is able to leave the apparatus during the Comet assay.We are looking for a business partner to further develop and commercialize Automated Method for the Processing of Slides as a viable alternative to commercially available techniques and to exploit its business and scientific potential as an efficient yet effective method for processing electrophoresis and high throughput Comet assay.
Benefit
Pump switching and chiller automates filing, emptying, chilling, and recirculation of all fluids provided as a fully automated processChilling and recirculation of the electrophoresis buffer through the electrophoresis tank would precisely maintain a lowered temperature (essential for electrophoresis)Racks no longer need to be removable, they can be integrated into the tankOvernight, chilled steps will not need to be performed in a fridgeLess time required for the operator to directly monitor every step of the processReduced waste and variability among slides
Market Application
The comet assay is increasingly used for genotoxicology testing by pharmaceutical companies which require high throughput speed and reliability in assays processing
Brochure