Abstract
Florida International University inventors created a methodology
to detect tumors primarily in pediatric patients. A combined point-detection
and imaging system device is utilized to detect brain tumors and their margins
to high accuracy based on distinct morphological, biochemical, and
physiological attributes to reduce the elimination of healthy brain tissue and
maximize the removal of tumor cells.Utilization of diffuse reflectance spectroscopy using long
wavelength light is effective in differentiating between tumors and normal
brain tissue. Preliminary in vivo studies show that adding regional hemodynamic
characteristics improved on differentiability. This enhancement in brain tumor
detection will improve patient prognoses and reduce financial and emotional
strain experienced by both the patients and their families.Current technologies for establishing tumor borders are
either not sensitive enough and result in tumor cells being left behind or are
expensive and difficult to implement. Due to these limitations, neurosurgeons
will often rely on subjective, inaccurate visual inspection. This technology
would be an addition to existing microscopes used for neurosurgery.
Benefit
Improves accuracy of detection of brain tumors and their margins than existing technologiesResults in minimal removal of normal brain tissueMaximal removal of tumor cellsDoes not require additional equipment to implement since it uses existing neurosurgical microscopes
Market Application
Pediatric brain tumor surgeryAid in pediatric epilepsy surgeryEasily adaptable to detection in other tissues.
Brochure
