The present disclosure is directed to compositions, methods of use, and methods of making, wherein the compositions contain one or more galloylated procyanidins having between two and five epicatechin monomers, wherein the one or more galloylated procyanidins include epicatechin( 4-8)-epicatechin-( 4-8)-epicatechin-gallate, catechin trimer gallate, catechin dimer digallate, or combinations thereof.Pharmaceuticals
