Ozlem Guzeloglu-Kayisli has uncovered a mechanism to help explain how stress in pregnant women can trigger preterm birth. The results of his work suggest that hormone FKBP51 plays a pivotal role in both term labor and stress-associated preterm birth.
“Prevention of idiopathic preterm birth by extending gestation even two or three weeks can benefit the newborn, because it provides critical time needed for the fetus’s lungs and brain to mature,” Guzeloglu-Kayisli said. “Our research indicates the importance of investigating the potential use of FKBP51 inhibitors as a targeted therapy.”
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