Monoclonal antibodies can be important tools for treating infectious diseases and other conditions. However, researchers at the FAMU-FSU College of Engineering and the National High Magnetic Field Laboratory have found that these products degrade under certain conditions, reducing their quality and shelf life.
“Air can get trapped in the IV bags ... or when administered by syringe the oil used in delivering the product can mix with the proteins in the therapeutic and alter its effectiveness,” says researcher Hadi Mohammadigoushki. The structure of the monoclonal antibodies causes this vulnerability. Once that process is better understood, steps can be taken to mitigate the risks.
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