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Analyzing the Molecular Mechanisms of Disease

FSU’s Robert Lazenby is developing tools to more accurately measure molecules within living cells and studying how cells communicate with each other through release and detection of chemical signals. Lazenby studies the way small molecules such as serotonin, dopamine, and glucose behave during cell communication, which affects functions such as growth, tissue repair, and immune responses. A breakdown in communication among cells is associated with a wide range of diseases.

“Our development of advanced nanoscale imaging tools and new analytical methods could lead to a means of testing the efficacy of medical treatments without relying on animal or human studies,” says Lazenby. “Our approach could also improve how we study diseases that are difficult to study with current imaging techniques.” The NIH Maximizing Investigators’ Research Award will support the lab’s work over a five-year period, maximizing stability, flexibility, and opportunities for discovery.

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