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Frederic Kaye
Professor
MD-MOLECULAR GENTCS / MICROBIO | COLLEGE-MEDICINE
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Hematology
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Ends
Title
07-2025
Signaling and Targeting of CRTC1-MAML2 Fusion Oncoprotein in Salivary Gland
Signaling and Targeting of CRTC1-MAML2 Fusion Oncoprotein in Salivary Gland
NATL INST OF HLTH NIDC
01-2025
Aberrant CRTC activation as a unique vulnerability of lung cancer with LKB1 inactivation
Aberrant CRTC activation as a unique vulnerability of lung cancer with LKB1 inactivation
NATL INST OF HLTH NC
10-2024
LIMITED STAGE SMALL CELL LUNG CANCER (LS-SCLC): A PHASE II/III RANDOMIZED STUDY OF CHEMORADIATION VERSUS CHEMORADIATION PLUS ATEZOLIZUMAB
LIMITED STAGE SMALL CELL LUNG CANCER (LS-SCLC): A PHASE II/III RANDOMIZED STUDY OF CHEMORADIATION VERSUS CHEMORADIATION PLUS ATEZOLIZUMAB
NATL INST OF HLTH NC
10-2024
LIMITED STAGE SMALL CELL LUNG CANCER (LS-SCLC): A PHASE II/III RANDOMIZED STUDY OF CHEMORADIATION VERSUS CHEMORADIATION PLUS ATEZOLIZUMAB
LIMITED STAGE SMALL CELL LUNG CANCER (LS-SCLC): A PHASE II/III RANDOMIZED STUDY OF CHEMORADIATION VERSUS CHEMORADIATION PLUS ATEZOLIZUMAB
NRG ONCOLOGY FOU
06-2024
Platinum-induced lipid reprogramming and tumor immune microenvironment in SCLC
Platinum-induced lipid reprogramming and tumor immune microenvironment in SCLC
NATL INST OF HLTH NC
02-2024
EA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNa
EA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNa
NATL INST OF HLTH NC
02-2024
EA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNa
EA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNa
NRG ONCOLOGY FOU
12-2023
SMK-1, a novel, conserved nuclear activator of DAF-16/FOXO tumor suppressor
SMK-1, a novel, conserved nuclear activator of DAF-16/FOXO tumor suppressor
AMER CANCER SO
06-2023
Editorship for "Journal of the National Cancer Institute"
Editorship for "Journal of the National Cancer Institute"
OXFORD UNIVERSITY PRESS
03-2023
Testing novel drug combination for pancreatic cancer
Testing novel drug combination for pancreatic cancer
FL DEPT OF HLTH BIOMED RES PGM/J&E KIN
03-2023
Good manufacturing Practice (GMP) production to allow Phase 1 clinical trial testing intralesional delivery of myxomavirus to patients with advanced small cell lung cancer
Good manufacturing Practice (GMP) production to allow Phase 1 clinical trial testing intralesional delivery of myxomavirus to patients with advanced small cell lung cancer
FL DEPT OF HLTH BIOMED RES PGM/J&E KIN
12-2021
The Role of Lipid Metabolism in Anti-tumor Immunity in Lung Cancer
The Role of Lipid Metabolism in Anti-tumor Immunity in Lung Cancer
AMER LUNG ASS
12-2021
Protein kinase signaling in cisplatin-resistant ASCL1-high SCLC
Protein kinase signaling in cisplatin-resistant ASCL1-high SCLC
US ARMY MED RES ACQUISITIO
12-2021
The role of NFIB-MAST1 signaling in mediating adaptive cisplatin resistance in SCLC
The role of NFIB-MAST1 signaling in mediating adaptive cisplatin resistance in SCLC
NATL INST OF HLTH NC
12-2021
Targeting MAST1-BCL2 signaling in small cell lung cancer
Targeting MAST1-BCL2 signaling in small cell lung cancer
LUNG CANCER RESEARCH FOUNDATION
12-2021
ufhcc-ioa cancer-aging collaborative team grants
ufhcc-ioa cancer-aging collaborative team grants
SHANDS TEACHING HOSPITA
06-2020
Targeting NFIB-MAST1 signaling in cisplatin-resistant small cell lung cancer
Targeting NFIB-MAST1 signaling in cisplatin-resistant small cell lung cancer
PARDEE FOU, ELSA
05-2020
Tumor Infiltrating lymphocyte adoptive T cell therapy for NSCLC
Tumor Infiltrating lymphocyte adoptive T cell therapy for NSCLC
AMER ASSO FOR CANCER RESEARCH
05-2020
Tumor Infiltrating lymphocyte adoptive T cell therapy for NSCLC
Tumor Infiltrating lymphocyte adoptive T cell therapy for NSCLC
MOFFITT CANCER CTR, H LE
05-2020
Signaling and targeting of CRTC1-MAML2 fusion oncoprotein in salivary gland tumor
Signaling and targeting of CRTC1-MAML2 fusion oncoprotein in salivary gland tumor
NATL INST OF HLT
05-2019
First-of-its-kind study of oncolytic virotherapy for Small Cell Lung Cancer (SCLC) using mouse models and human ex-vivo intralesional analyses
First-of-its-kind study of oncolytic virotherapy for Small Cell Lung Cancer (SCLC) using mouse models and human ex-vivo intralesional analyses
FL DEPT OF HLTH BIOMED RES PGM/J&E KIN
02-2019
ET-CTN with Phase 2 Emphasis
ET-CTN with Phase 2 Emphasis
NATL INST OF HLTH NC
02-2019
ET-CTN with Phase 2 Emphasis
ET-CTN with Phase 2 Emphasis
UNIV OF PITTSBURG
09-2018
Epha2 -/- NK Cell Therapy against Malignant Pleural Mesothelioma
Epha2 -/- NK Cell Therapy against Malignant Pleural Mesothelioma
US ARMY MED RES ACQUISITIO
06-2018
4th International Conference on Malignant Salivary Gland Tumors
4th International Conference on Malignant Salivary Gland Tumors
NATL INST OF HLTH NIDC
03-2018
A novel noncoding RNA and human lung cancers with inactivated LKB1 signaling
A novel noncoding RNA and human lung cancers with inactivated LKB1 signaling
NATL INST OF HLTH NC
03-2018
TIGER-3: A Phase 3, Open-label, Multicenter, Randomized Study of Oral Rociletinib (CO-1686) Monotherapy Versus Single-agent Cytotoxic Chemotherapy in Patients with Mutant EGFR Non-small Cell Lung Cancer (NSCLC) after Failure of at Least 1 Previous
TIGER-3: A Phase 3, Open-label, Multicenter, Randomized Study of Oral Rociletinib (CO-1686) Monotherapy Versus Single-agent Cytotoxic Chemotherapy in Patients with Mutant EGFR Non-small Cell Lung Cancer (NSCLC) after Failure of at Least 1 Previous
CLOVIS ONCOLOGY INC
03-2018
TIGER-3: A Phase 3, Open-label, Multicenter, Randomized Study of Oral Rociletinib (CO-1686) Monotherapy Versus Single-agent Cytotoxic Chemotherapy in Patients with Mutant EGFR Non-small Cell Lung Cancer (NSCLC) after Failure of at Least 1 Previous
TIGER-3: A Phase 3, Open-label, Multicenter, Randomized Study of Oral Rociletinib (CO-1686) Monotherapy Versus Single-agent Cytotoxic Chemotherapy in Patients with Mutant EGFR Non-small Cell Lung Cancer (NSCLC) after Failure of at Least 1 Previous
PRA HEALTH SCIENCES
12-2017
A Phase III, Open Label, Randomized Study of AZD9291 versus Platinum-Based Doublet Chemotherapy for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer whose Disease has Progressed with Previous Epidermal Growth
A Phase III, Open Label, Randomized Study of AZD9291 versus Platinum-Based Doublet Chemotherapy for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer whose Disease has Progressed with Previous Epidermal Growth
ASTRAZENEC
12-2017
A Phase III, Open Label, Randomized Study of AZD9291 versus Platinum-Based Doublet Chemotherapy for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer whose Disease has Progressed with Previous Epidermal Growth
A Phase III, Open Label, Randomized Study of AZD9291 versus Platinum-Based Doublet Chemotherapy for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer whose Disease has Progressed with Previous Epidermal Growth
CLINICAL FINANCIAL SERVICES
10-2016
An Open-label, Randomized Phase IIb/III Active Control Study of Second-line HyperAcute?-Lung (tergenpumatucel-L) Immunotherapy versus Docetaxel in Progressive or Relapsed Non-Small Cell Lung Cancer
An Open-label, Randomized Phase IIb/III Active Control Study of Second-line HyperAcute?-Lung (tergenpumatucel-L) Immunotherapy versus Docetaxel in Progressive or Relapsed Non-Small Cell Lung Cancer
NEW LINK GENETICS
07-2016
Small Cell Lung Cancer, sponsor code 7275
Small Cell Lung Cancer, sponsor code 7275
UF FO
11-2015
A novel ubiquitin ligase in epithelial maintenance
A novel ubiquitin ligase in epithelial maintenance
FL DEPT OF HLTH BIOMED RES PGM/J&E KIN
11-2015
T cell engineering targeting small cell lung cancer
T cell engineering targeting small cell lung cancer
FL DEPT OF HLTH BANKHEAD-COLEY CANCER R
05-2015
Molecular and Epidemiologic Characterization of Salivary
Molecular and Epidemiologic Characterization of Salivary
UNIV OF TEXA
05-2015
H3E-US-S130
H3E-US-S130
LILLY US
04-2015
IMGN0007
IMGN0007
ImmunoGen, Inc
07-2014
AML study contract
AML study contract
ANDAMAN THERAPEUTICS
05-2012
Molecular and Edidemiology Characterization of Salivary
Molecular and Edidemiology Characterization of Salivary
UNIV OF TEXA
06-2011
Center of Excellence in Lung Transplantation
Center of Excellence in Lung Transplantation
FL CLINICAL PRACTICE ASS
05-2011
Molecular and Epidemiology Characterization of Salivary
Molecular and Epidemiology Characterization of Salivary
UNIV OF TEXA
05-2010
Molecular and Epidemiology Characterization of Salivary
Molecular and Epidemiology Characterization of Salivary
UNIV OF TEXA
Publications
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Co-Investigator Network
Inactive Expert
Henry Baker
Hazel Kitzman Professor and Chair
University of Florida
MD-MOLECULAR GENTCS / MICROBIO, College-Medicine
hvbaker@ufl.edu
Christopher Batich
PROF
University of Florida
EG-MATERIALS SCI ENGINEERING, College-Medicine and Engineering
cbati@ufl.edu
Inactive Expert
Maher Baz
University of Florida
MD-PULMONARY-TRANSPLANT, College-Medicine
-
Thomas Beaver
Professor
University of Florida
Surgery, College Of Medicine
thomas.beaver@surgery.ufl.edu
Inactive Expert
Victoria Bird
Assistant Prof
University of Florida
MD-CANCER CENTER, College-Medicine
-
Sanford Boye
Associate Scientist, Director of Vector Core
University of Florida
MD-POWELL GENE THERAPY CENTER, College-Medicine
sboye@ufl.edu
Inactive Expert
Mark Brantly
Professor
University of Florida
MD-MOLECULAR GENTCS / MICROBIO, College-Medicine
brantml@medicine.ufl.edu
Inactive Expert
Lung-Ji Chang
PROFESSOR
University of Florida
MD-MOLECULAR GENTCS / MICROBIO, College-Medicine
lchang@mgm.ufl.edu
Brian Cleaver
Associate Program Director
University of Florida
MD-CTSI-SVC CGMP GENE THERAPY, College-Medicine
bcleaver@ufl.edu
Christopher Cogle
Associate Professor of Medicine
University of Florida
MD-HEMATOLOGY/ONCOLOGY, University Of Florida
c@ufl.edu
Thomas George
AssociateProfessor - Physician
University of Florida
MD-HEMATOLOGY/ONCOLOGY, College-Medicine
tgeorge@ufl.edu
Inactive Expert
Robert Hromas
University of Florida
MD-MEDICINE CHAIRMAN, College-Medicine
-
Inactive Expert
Hanbo Hu
Assistant Scientist
University of Florida
MD-PULMONARY-TRANSPLANT, College-Medicine
hanbohu@ufl.edu
Inactive Expert
Michael Jantz
PROFESSOR
University of Florida
MD-PULMONARY MEDICINE, College-Medicine
majantz@ufl.edu
Inactive Expert
Lingtao Jin
University of Florida
MD-ANATOMY-GENERAL, College-Medicine
ljin1@ufl.edu
Dennie Jones
Professor
University of Florida
MD-HEMATOLOGY/ONCOLOGY, College-Medicine
dvjonesii@ufl.edu
Andrew Judge
Professor
University of Florida
HP-PHYSICAL THERAPY, College-Publ Hlth / Hlth Profs
arjudge@ufl.edu
Inactive Expert
Jae Kim
Professor
University of Florida
MD-ANATOMY-GENERAL, College-Medicine
uwsolutn@ufl.edu
Jonathan Licht
UF Health Cancer Center Director and The Marshall E. Rinker Senior Chair
University of Florida
MD-HEMATOLOGY/ONCOLOGY-ONCOL, College-Medicine
jdlicht@ufl.edu
Inactive Expert
Chen Liu
Professor
University of Florida
MD-PATHOLOGY, College-Medicine
liu@pathology.ufl.edu
Jianrong Lu
Associate Professor
University of Florida
MD-BIOCHEM / MOLECULAR BIOL, University Of Florida
jrlu@ufl.edu
Debra Lyon
Professor and Kirbo Endowed Chair
University of Florida
NR-BNS-BIOBEHAVORIAL NUR SCI, College-Nursing
delyon@ufl.edu
Todd Manini
Professor; Division Chief of Clinical and Population Health Integration; Co-Director of the Claude D. Pepper Older Americans Independence Center
University of Florida
MD-HOBI-BIOMED INFORMATICS, College-Medicine
tmanini@ufl.edu
Merry Markham
Clinical Professor
University of Florida
MD-HEMATOLOGY/ONCOLOGY, College-Medicine
merry.markham@medicine.ufl.edu
Inactive Expert
Douglas McFadden
Professor
University of Florida
MD-MOLECULAR GENTCS / MICROBIO, College-Medicine
grantmcf@ufl.edu
Inactive Expert
Susan Mcgorray
Research Assistant Professor
University of Florida
PHHP-COM BIOSTATISTICS, Phhp-Com Integrated Programs
spmcg@ufl.edu
Hiren Mehta
Professor
University of Florida
MD-PULMONARY MEDICINE, College-Medicine
hjm2@ufl.edu
Inactive Expert
Kamal Mohammed
Research Associate Professor
University of Florida
MD-PULMONARY MEDICINE, College-Medicine
mkamal@medicine.ufl.edu
Inactive Expert
Nissin Moussatche
PhD
University of Florida
MD-HEMATOLOGY/ONCOLOGY, College-Medicine
nissin@ufl.edu
Inactive Expert
Nasreen Najmunnisa
ASSISTANT PROFESSOR
University of Florida
Ph.D-PULMONARY MEDICINE, College-Medicine
Nasreen.Najmunnisa@medicine.ufl.edu
Inactive Expert
J Patel
PROFESSOR
University of Florida
MD-PULMONARY-TRANSPLANT, College-Medicine
pateljm@medicine.ufl.edu
Mattia Prosperi
Professor and Associate Dean for AI and Innovation
University of Florida
HP-OFFICE OF THE DEAN, College-Publ Hlth / Hlth Profs
m.prosperi@ufl.edu
Gregory Schultz
PROFESSOR
University of Florida
MD-OBGYN-WOUND RESEARCH CTR, College-Medicine
schultzg@ufl.edu
Shinichi Someya
Associate Professor
University of Florida
MD-PHYSIOLOGY AND AGING, College-Medicine
someya@ufl.edu
Hugh Sweeney
Myology Institute Director & Eminent Scholar Professor
University of Florida
MD-PHARMACOLOGY / THERAPEUTICS, College-Medicine
lsweeney@ufl.edu
Inactive Expert
Jose Trevino
Associate Professor
University of Florida
MD-SURGERY-SURGONC-PBS, College-Medicine
trevinojg@ufl.edu
Lizi Wu
Ph.D.
University of Florida
MD-MOLECULAR GENTCS / MICROBIO, College-Medicine
lzwu@ufl.edu
Inactive Expert
ChangQing Xia
Assistant Professor
University of Florida
MD-PATHOLOGY-GENERAL, College-Medicine
xia@pathology.ufl.edu
Rui Xiao
Associate Professor
University of Florida
MD-PHYSIOLOGY AND AGING, College-Medicine
rxiao@ufl.edu
Maria Zajac-Kaye
Haskel Hess Professor
University of Florida
MD-ANATOMY-GENERAL, College-Medicine
mzajackaye@ufl.edu
Serge Zolotukhin
Professor
University of Florida
MD-PEDS-CELL / MOLEC THERP DIV, College-Medicine
szlt@ufl.edu
Expertnet Author Network
Experts within Florida Expertnet that have co-authored works with Frederic Kaye.
Jiang Bian
Professor and Division Director Of Biomedical Informatics; Chief Data Scientist & Chief Research Information Officer, Uf Health
University of Florida
Md-Hobi-Biomed Informatics, College-Medicine
bianjiang@ufl.edu
Works Co-Authored: 128
Dejana Braithwaite
Professor and Division Chief, Population Health Sciences, Department Of Surgery
University of Florida
Md-Surg-Population Health Sci, College-Medicine
dbraithwaite@ufl.edu
Works Co-Authored: 132
Irene Estores
Associate Professor, Residency Program Director
University of Florida
Md-Physical Medicine & Rehab, College-Medicine
ime@ufl.edu
Works Co-Authored: 34
Kristianna Fredenburg
Ast Prof
University of Florida
Md-Pathology-General, College-Medicine
kfredenburg@pathology.ufl.edu
Works Co-Authored: 28
Thomas George
Associateprofessor - Physician
University of Florida
Md-Hematology/Oncology, College-Medicine
tgeorge@ufl.edu
Works Co-Authored: 59
Inactive Expert
Priya Gopalan
Ast Prof
University of Florida
Md-Hematology/Oncology, College-Medicine
Works Co-Authored: 5
Yi Guo
Associate Professor
University of Florida
Md-Hobi-General, College-Medicine
yiguo@ufl.edu
Works Co-Authored: 81
Inactive Expert
Bruno Hochhegger
Associate Director, Advisory Board Member, Rail Laboratory; Professor Of Radiology and Vice Chair Of Research, Department Of Radiology
University of Florida
Md-Radiology-Chest, College-Medicine
Works Co-Authored: 4
Inactive Expert
Bradford Hoppe
Associate Professor
University of Florida
Md-Radiation Oncology, College-Medicine
Works Co-Authored: 177
Robert Huigens
Associate Professor
University of Florida
Ph-Medicinal Chemistry, College-Pharmacy
rwhuigens@ufl.edu
Works Co-Authored: 12
Dennie Jones
Professor
University of Florida
Md-Hematology/Oncology, College-Medicine
dvjonesii@ufl.edu
Works Co-Authored: 6
Jeb Justice
Associate Professor, Chief, Division Of Rhinology & Skull Base Surgery, Associate Residency Program Director, App Director
University of Florida
Md-Otolaryngology, College-Medicine
jeb.justice@ent.ufl.edu
Works Co-Authored: 41
Inactive Expert
Faming Liang
University of Florida
Phhp-Com Biostatistics, Phhp-Com Integrated Programs
Works Co-Authored: 4
Jonathan Licht
Uf Health Cancer Center Director and The Marshall E. Rinker Senior Chair
University of Florida
Md-Hematology/Oncology-Oncol, College-Medicine
jdlicht@ufl.edu
Works Co-Authored: 14
Inactive Expert
Judith Lightsey
Clinical Assistant Professor
University of Florida
Md-Radiation Oncology, College-Medicine
Works Co-Authored: 16
Inactive Expert
Xiaoping Luo
Laboratory Mgr
University of Florida
Md-Obgyn-Wound Research Center, College-Medicine
Works Co-Authored: 1
Merry Markham
Clinical Professor
University of Florida
Md-Hematology/Oncology, College-Medicine
merry.markham@medicine.ufl.edu
Works Co-Authored: 12
Robert Mckenna
Professor & Director Center For Structural Biology
University of Florida
Md-Biochem / Molecular Biol, College-Medicine
rmckenna@ufl.edu
Works Co-Authored: 420
Inactive Expert
Elham Nasri
University of Florida
Md-Pathology-General, College-Medicine
Works Co-Authored: 3
Paul Okunieff
Professor and Chair
University of Florida
Md-Radiation Oncology, College-Medicine
pokunieff@ufl.edu
Works Co-Authored: 24
Deidre Pereira
Associate Professor
University of Florida
Clinical and Health Psychology, College Of Public Health and Health Professions
dpereira@phhp.ufl.edu
Works Co-Authored: 298
Inactive Expert
Yi Qiu
Assistant Professor
University of Florida
Md-Anatomy-General, College-Medicine
Works Co-Authored: 19
Adrian Roitberg
Professor
University of Florida
Ls-Chemistry-General, College-Liberal Arts/Sciences
roitberg@ufl.edu
Works Co-Authored: 24
Inactive Expert
Natalie Silver
Assistant Professor
University of Florida
Md-Otolaryngology, College-Medicine
Works Co-Authored: 27
Inactive Expert
Adaixa Wilborn
Consultant Staff - Pereira
University of Florida
Hp-Clinical / Hlth Psychology, College-Publ Hlth / Hlth Profs
Works Co-Authored: 2
Lizi Wu
Ph.D.
University of Florida
Md-Molecular Gentcs / Microbio, College-Medicine
lzwu@ufl.edu
Works Co-Authored: 7
Anamaria Yeung
University of Florida
Md-Radiation Oncology, College-Medicine
areyna@ufl.edu
Works Co-Authored: 107
Maria Zajac-Kaye
Haskel Hess Professor
University of Florida
Md-Anatomy-General, College-Medicine
mzajackaye@ufl.edu
Works Co-Authored: 6
Lei Zhou
Professor
University of Florida
Md-Molecular Gentcs / Microbio, College-Medicine
leizhou@ufl.edu
Works Co-Authored: 99
Websites
ORCID 0000-0001-8565-1854
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Contact Information
fkaye@ufl.edu
3522737832
PO Box 100278 GAINESVILLE, FL 32610-0278
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