Expert Profile

Share QR code Edit Profile

Jerome Breslin

Professor

MOLECULAR PHARMACOLOGY AND PHYSIOLOGY | MORSANI COLLEGE OF MEDICINE

View:

Select
All (all in one) Research Terms and Keywords Background Publications Activities Stories Technologies Network Websites Contact

All
Research
Background
Publications
Activities
Stories
Technologies
Network
Websites
Contact

Research Terms & Keywords

Research Terms

Cell Biology Cardiovascular System Lymphatic System Physiology Pharmacology Microscopy

Industries

Medical Devices Pharmaceuticals

Research Projects

Ends

Title

12-2027

University of South Florida Summer Undergraduate Research Program in Cardiovascular Biology AHA SURF 2025 University of South Florida Summer Undergraduate Research Program in Cardiovascular Biology AHA SURF 2025

American Heart Association (National)

06-2027

RESUBM: Obesity, Metabolic Syndrome, and Lymphatic Dysfu RESUBM: Obesity, Metabolic Syndrome, and Lymphatic Dysfu

National Institutes of Health

03-2027

Microvascular Leakage in Hemorrhagic Shock and Trauma Microvascular Leakage in Hemorrhagic Shock and Trauma

National Institutes of Health

12-2024

University of South Florida Summer Undergraduate Researc University of South Florida Summer Undergraduate Researc

American Heart Association

08-2023

Human Resistance Artery Functional Changes with Alcohol Human Resistance Artery Functional Changes with Alcohol

National Institutes of Health

06-2021

S1P-fluid therapy to reduce hemorrhagic shock & intoxica S1P-fluid therapy to reduce hemorrhagic shock & intoxica

National Institutes of Health

01-2021

University of South Florida Heart Institute Summer Under University of South Florida Heart Institute Summer Under

American Heart Association

06-2017

Signaling Mechanisms Controlling Sphingosine-1 Phosphate induced Microvascular Barrier Enhancement Signaling Mechanisms Controlling Sphingosine-1 Phosphate induced Microvascular Barrier Enhancement

American Heart Association (National)

06-2016

Regulatory Mechanisms for Resolution of Inflammatory Microvascular Leakage Regulatory Mechanisms for Resolution of Inflammatory Microvascular Leakage

National Heart, Lung, and Blood Institute

07-2013

Impact of Alcohol on Hemorrhagic Shock-Induced Microvascular Dysfunction Impact of Alcohol on Hemorrhagic Shock-Induced Microvascular Dysfunction

National Institute on Alcohol Abuse and Alcoholism

Degrees

Ph.D., Pharmacology and Physiology

University of Medicine and Dentistry of New Jersey ▪ 2002
M.S., Biology

Seton Hall University ▪ 1998
B.A., Biological Sciences

Rutgers University ▪ 1993

Awards & Honors

The Microcirculatory Society Travel Award for Young Investigators

The Microcirculatory Society, Inc. ▪ 2012
NIH Loan Repayment Award

NIH/NHLBI ▪ 2009
August Krogh Young Investigator Award

The Microcirculatory Society, Inc. ▪ 2006
Lymphatic Research Foundation/Susan G. Komen Research Scholarship

Lymphatic Research Foundation ▪ 2006
Caroline tum Suden/Frances A. Hellebrandt Professional Opportunity Award

American Physiological Society ▪ 2001

Publications

OpenAlex
Expert Provided
Search Engines

Last updated on 7/22/25. See our OpenAlex FAQ for more about this data.

Reduced RhoA activity mediates acute alcohol intoxication-induced inhibition of lymphatic myogenic constriction despite increased cytosolic [Ca(2+) ]. Souza-Smith FM, Molina PE, Breslin JW. Microcirculation. 2012 Dec 13. doi: 10.1111/micc.12032. [Epub ahead of print] PMID: 23237297

Measurement of cytosolic Ca2+ in isolated contractile lymphatics. Souza-Smith FM, Kurtz KM, Breslin JW. J Vis Exp. 2011 Dec 8;(58). doi:pii: 3438. 10.3791/3438. PMID: 22214883

ISG15 disrupts cytoskeletal architecture and promotes motility in human breast cancer cells. Desai SD, Reed RE, Burks J, Wood LM, Pullikuth AK, Haas AL, Liu LF, Breslin JW, Meiners S, Sankar S. Exp Biol Med (Maywood). 2012 Jan 1;237(1):38-49. doi: 10.1258/ebm.2011.011236. Epub 2011 Dec 20. PMID: 22185919

Study of the actin cytoskeleton in live endothelial cells expressing GFP-actin. Doggett TM, Breslin JW. J Vis Exp. 2011 Nov 18;(57). doi:pii: 3187. 10.3791/3187. PMID: 22126853

ROCK and cAMP promote lymphatic endothelial cell barrier integrity and modulate histamine and thrombin-induced barrier dysfunction. Breslin JW. Lymphat Res Biol. 2011 Mar;9(1):3-11. doi: 10.1089/lrb.2010.0016. PMID: 21417762

Search Google Scholar for Jerome Breslin

OpenAlex Works Search

Memberships

Gulf Coast Physiological Society, Treasurer; 2011 - 2012

American Heart Association, Member; 2008 - present

American Association for the Advancement of Science, Member; 2005 - present

American Society for Cell Biology, Member; 2003 - present

American Physiological Society, Member; 2001 - present

New York Academy of Sciences, Member; 2001 - 2003

The Microcirculatory Society, Inc., Member; 2001 - present

Peer Review Positions

ZRG1 DKUS D 57; PAR Panel: Lymphatics in Health and Disease in the Digestive, Urinary, Cardiovascular and Pulmonary Systems D , National Institutes of Health; 2012 - 2012

Microcirculation, Editorial Board, The Microcirculatory Society, Inc.; 2011 - 2015

Stories

Illuminating the Lymphatic System’s Role in Disease

#LymphLIGHT

Illuminating the Lymphatic System’s Role in Disease

#LymphLIGHT

Technologies

Compositions And Methods For Modulating The Endothelial Barrier

Competitive Advantages: Increased endothelial cell anaerobic glycolysis, Edema prevention, Enhanced endothelial barrier function, A potential treatment for many diseases. Disclosed are compositions and methods for modulating endothelial barrier functionUSF inventors have developed a method which utilizes agents that activate s1. The activation of s1 encourages the metabolic production of ATP to be shifted from oxidative mechanisms to anaerobic glycolysis. Our data show for the first time that s1 activation leads to enhanced glycolytic ATP production which is tightly linked to endothelial barrier integrity. Therefore, s1 can be utilized as a novel therapeutic target for ameliorating endothelial barrier dysfunction caused by ischemia. This invention is applicable to any disease involving endothelial dysfunction, including but not limited to diabetes, peripheral vascular disease, heart disease, hypertension, venous thrombosis, insulin resistance, ischemic diseases of the gut, stroke, sepsis, chronic inflammatory diseases, and severe viral diseases.

Expertnet Author Network

Experts within Florida Expertnet that have co-authored works with Jerome Breslin.

Walter Murfee

Prof

University of Florida

Eg-Biomedical Engineering, College-Engineering

wmurfee@bme.ufl.edu

Works Co-Authored: 151

Inactive Expert

Kendall Morris

Professor

Jerome Breslin

Professor

MOLECULAR PHARMACOLOGY AND PHYSIOLOGY | MORSANI COLLEGE OF MEDICINE

Research Terms & Keywords

Research Projects

Degrees

Awards & Honors

Publications

Memberships

Peer Review Positions

Stories

Technologies

Expertnet Author Network

Websites

Contact Information

Additional Contact Information

About

Discover

Connect

Keyword Search

Browse by STEM