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Nathalie Clement

Associate Program Director And Associate Professor

MD-CHILD HEALTH RES INSTITUTE | COLLEGE-MEDICINE

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12-2022

Sarepta TO #1: Support of PGTC Cores Sarepta TO #1: Support of PGTC Cores

10-2022

Quality Control ddPCR assay development Quality Control ddPCR assay development

12-2021

Task Order 3 - Access and Transfer of rHSV-AAV9 and rHSV-CB-hFXN Production and Testing Methods and Associated Materials Task Order 3 - Access and Transfer of rHSV-AAV9 and rHSV-CB-hFXN Production and Testing Methods and Associated Materials

12-2021

AAV9-CK8-uDys5 Samples testing AAV9-CK8-uDys5 Samples testing

12-2021

TO #1 - Access and Transfer of rAAV9-CMV-hAADC Production and Testing Methods# TO #1 - Access and Transfer of rAAV9-CMV-hAADC Production and Testing Methods#

07-2021

Phase II Study of AAV9-GAA Gene Transfer in Pompe Disease Phase II Study of AAV9-GAA Gene Transfer in Pompe Disease

06-2021

PTC TO #3 - AAV2-AADC Stability Study 96 months PTC TO #3 - AAV2-AADC Stability Study 96 months

06-2021

Processing and testing for FA AAV and HSV Processing and testing for FA AAV and HSV

04-2021

Solid Task Order 22 - Process and Development for reducing residual impurities in AAV stocks Solid Task Order 22 - Process and Development for reducing residual impurities in AAV stocks

12-2020

PTC Task Order #2 - AAV2-AADC Stability Study PTC Task Order #2 - AAV2-AADC Stability Study

12-2020

Solid Task Order #14 - Analytical testing of rAAV9-CK8-hDys5 samples Solid Task Order #14 - Analytical testing of rAAV9-CK8-hDys5 samples

12-2019

Production and Testing of rAAV9-DES-hGAA Production and Testing of rAAV9-DES-hGAA

12-2019

Testing of rAAV9-CK8-hDys5 Lots Testing of rAAV9-CK8-hDys5 Lots

12-2019

Task Order #13 - Evaluation of SGT-01 in Neonatal NHP using Immune Modulation Task Order #13 - Evaluation of SGT-01 in Neonatal NHP using Immune Modulation

12-2019

Clinical trial readiness for AAV-mediated gene therapy in Friedreich#s Ataxia Clinical trial readiness for AAV-mediated gene therapy in Friedreich#s Ataxia

11-2019

Process Development for AAV Manufacturing of AAV-CB-hFXN Process Development for AAV Manufacturing of AAV-CB-hFXN

08-2019

Gemini TO #1 - Pilot AAV2-CFI vector manufacturing Gemini TO #1 - Pilot AAV2-CFI vector manufacturing

07-2019

Voyant TO #1 - GMP Site Audit Voyant TO #1 - GMP Site Audit

06-2019

HSV-AAV2/9 Seed Stock transfer HSV-AAV2/9 Seed Stock transfer

06-2019

Quality Control Testing of rAAV2-CMV-hAADC Lot # 2004-101 Quality Control Testing of rAAV2-CMV-hAADC Lot # 2004-101

02-2019

AAV5-Cassette Work and sBHK Master Cell Bank AAV5-Cassette Work and sBHK Master Cell Bank

09-2018

Task Order 1 - Reagents preparations and pilot production of rAAV3 for Hemophilia Task Order 1 - Reagents preparations and pilot production of rAAV3 for Hemophilia

08-2018

Solid Task Order #20 UFL TR-032 technology Transfer Solid Task Order #20 UFL TR-032 technology Transfer

01-2018

STABILITY TESTING OF CLINICAL rAAV9-Des-hGAA LOTS STABILITY TESTING OF CLINICAL rAAV9-Des-hGAA LOTS

12-2017

Qualification of Q-PCR protocol for the determination of vector genome in rAAV9-CK8-hDys5 samples Qualification of Q-PCR protocol for the determination of vector genome in rAAV9-CK8-hDys5 samples

12-2017

TO #1 - Production of rAAV9-CB-hGal Test Article TO #1 - Production of rAAV9-CB-hGal Test Article

12-2017

Quality Control Testing of rAAV2-CMV-hAADC Lot # 2004-101 Quality Control Testing of rAAV2-CMV-hAADC Lot # 2004-101

12-2017

Powell Gene Therapy Center Vector Core Production - Fede Powell Gene Therapy Center Vector Core Production - Fede

12-2017

Manufacturing rAAV9-EF1 Using NHGRI#s Proprietary Materials Manufacturing rAAV9-EF1 Using NHGRI#s Proprietary Materials

06-2017

Quality Control Testing of scAAV2(Y444,500,730F-smCBA-PIND4v2 Lot#2008-100 Quality Control Testing of scAAV2(Y444,500,730F-smCBA-PIND4v2 Lot#2008-100

03-2017

Task Order #10 - Production of rAAV9-CK8-hDys5 Test Article using the Herpes-simplex virus platform.# Task Order #10 - Production of rAAV9-CK8-hDys5 Test Article using the Herpes-simplex virus platform.#

02-2017

Powell Gene Therapy Center Vector Core Production - Non Powell Gene Therapy Center Vector Core Production - Non

01-2017

TO #11 - Production of rAAV9-CK8-hDys5 Test Article using the Herpes-simplex virus platform TO #11 - Production of rAAV9-CK8-hDys5 Test Article using the Herpes-simplex virus platform

01-2017

HSV production technology transfer to paragon bioservices HSV production technology transfer to paragon bioservices

12-2016

TESTING OF HEK 293 MASTER CELL BANK, LOT # 3006-0031 TESTING OF HEK 293 MASTER CELL BANK, LOT # 3006-0031

12-2016

Process Development for the production of rAAV9-ck8-hDys5 test article using the herpes-simplex virus platform Process Development for the production of rAAV9-ck8-hDys5 test article using the herpes-simplex virus platform

12-2016

Project Development Planning Project Development Planning

09-2016

Production and Testing of rAAV9-ck8-hDys5 Test Article Production and Testing of rAAV9-ck8-hDys5 Test Article

07-2016

Purchase of Process Development Laboratory Equipment - Task Order #3 Purchase of Process Development Laboratory Equipment - Task Order #3

03-2016

Quality Control Testing of scAAV2(Y444,500,730F-smCBA-PI Quality Control Testing of scAAV2(Y444,500,730F-smCBA-PI

12-2015

18 month stability testing 18 month stability testing

12-2015

24 Months Stability Testing 24 Months Stability Testing

12-2015

Dry Ice Shipping Dry Ice Shipping

10-2015

Testing of rAAV2-CMV-hAADC Testing of rAAV2-CMV-hAADC

08-2015

CFGSDR: AAV2/8-GPE-h-G6PC by transfection for 3E13 vg CFGSDR: AAV2/8-GPE-h-G6PC by transfection for 3E13 vg

08-2015

Production of rAAV stocks Production of rAAV stocks

08-2015

Glygenix: AAV2/8-GPE-h-G6PC by transfection for 3E13 vg Glygenix: AAV2/8-GPE-h-G6PC by transfection for 3E13 vg

12-2014

Prep and Testing of rHSV/rAAV-CFTR Prep and Testing of rHSV/rAAV-CFTR

04-2014

UMIAMI: John Guy Testing Part 1 UMIAMI: John Guy Testing Part 1

03-2014

Production and characterization of a Test Article consis Production and characterization of a Test Article consis

12-2013

Preparation and Testing of Plasma DNA for rAAV Productio Preparation and Testing of Plasma DNA for rAAV Productio

09-2013

Biomarin 701 Laboratory Services Agreement Biomarin 701 Laboratory Services Agreement

07-2013

Development, Manufacturing, and testing of scAAV2 Development, Manufacturing, and testing of scAAV2

08-2012

Development, Manufacturing, and testing of scAAV2 Development, Manufacturing, and testing of scAAV2

12-2010

AGTC License Agreement for Research Materials AGTC License Agreement for Research Materials

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Co-Investigator Network

Sanford Boye

Associate Scientist, Director of Vector Core

University of Florida

MD-POWELL GENE THERAPY CENTER, College-Medicine

sboye@ufl.edu

Barry Byrne

PROF & ASO CHR

University of Florida

MD-COGNITAL HRT CTR EXCELLENCE, College-Medicine

byrne@gtc.ufl.edu

Brian Cleaver

Associate Program Director

University of Florida

MD-CTSI-SVC CGMP GENE THERAPY, College-Medicine

bcleaver@ufl.edu

Kirsten Coleman

AST DIR, Research Admin

University of Florida

MD-POWELL GENE THERAPY CENTER, College-Medicine

kee2000@ufl.edu

Manuela Corti

Associate Professor

University of Florida

MD-CHILD HEALTH RES INSTITUTE, College-Medicine

m.corti@peds.ufl.edu

Barbara Smith

Research Asst. Professor

University of Florida

HP-PHYSICAL THERAPY, College-Publ Hlth / Hlth Profs

bksmith@ufl.edu

Glenn Walter

PROFESSOR

University of Florida

MD-PHYSIOLOGY AND AGING, College-Medicine

glennw@ufl.edu

Websites

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Contact Information

nclement@peds.ufl.edu

3522735522

1200 NEWELL DRIVE
ACADEMIC RESEARCH BUILDING RG-187
PO BOX 100296
GAINESVILLE, FL 32610-3012

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Nathalie Clement

Associate Program Director And Associate Professor

MD-CHILD HEALTH RES INSTITUTE | COLLEGE-MEDICINE

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