Research Terms
Keywords
Mechanical Ventilation Muscular Dystrophy Neuromuscular Disease Plasticity Rehabilitation Respiratory Muscles
Industries
Smith BK, Corti M, Martin AD, Fuller DD, Byrne BJ. Altered activation of the diaphragm in late-onset Pompe disease. Respiratory Physiology & Neurobiology. Manuscript in Press. PMID: 26612101. PMCID: in process.
Smith BK, Renno M, Green MM, Sexton T, Martin D, Corti M, Byrne BJ. Respiratory motor function in individuals with centronuclear myopathy and ventilatory insufficiency. Muscle and Nerve. 2016; 52(2): 214-21. PMID: 26351754. PMCID: PMC4718843.
Corti M, Smith BK, Falk D, Fuller DD, Subramony SH, Byrne BJ, Christou EA. Altered activation of the tibialis anterior in individuals with Pompe disease: implications for motor unit dysfunction. Muscle and Nerve. 2015; 51(6): 877-83. PMID: 25186912. PMCID: PMC4348349.
Corti M, Elder M, Falk D, Lawson LA, Smith BK, Nayak B, Conlon T, Clement N, Erger K, Lavassani E, Green M, Doerfler P, Herzog R, Byrne BJ. B-cell depletion is protective against anti-AAV capsid immune response: a human subject case study. Molecular Therapy Methods: Clinical Development. 2014; 1:pii:14033. PMID: 25541616. PMC4275004.
Byrne BJ, Collins S, Mah C, Smith B, Conlon T, Martin AD, Corti M, Cleaver B, Islam S, Lawson LA. Phase I/II trial of diaphragm delivery of recombinant adeno-associated virus acid alpha-glucosidase (rAAV1-CMV-GAA) gene vector in patients with Pompe disease. Human Gene Therapy: Clinical Development. 2014: 25(3): 143-63. PMID: 25238277. PMC: in process.
Smith BK, Mathur S, Ye F, Martin AD, Truelson S, Vandenborne K, Davenport PW. Intrinsic Transient Trachial Occlusion Training Facilitates Myogenic Remodeling in Rodent Parasternal Intercostal Fibers. Journal of Rehabilitation Research and Development. 2014; 51(5): 841-54. PMID: 25509059. PMC4269303.
Ahn B, Beaver T, Martin T, Hess P, Brumback BA, Ahmed S, Smith BK, Leeuwenburgh C, Martin AD, Ferreira LF. Phrenic nerve stimulation increases human diaphragm fiber force after cardiothoracic surgery. American Journal of Respiratory and Critical Care Medicine. 2014; 190(7): 837-9. PMID: 25271750. PMC4299610.
Ye F, McCoy SC, Ross HH, Bernardo JA, Beharry AW, Senf SA, Judge AR, Beck DT, Conover CF, Cannady DF, Smith BK, Yarrow JF, Borst SE. Transcriptional regulation of myotrophyic actions by testosterone and trenbolone on androgen-responsive muscle. Steroids. 2014; 87: 59-66. PMID: 24928725
Smith BK, Goddard M, Childers MK. Respiratory assessment in centronuclear myopathies. Muscle and Nerve. 2014; 50 (3): 315-26. PMID: 24668768. PMC4140950
Martin AD, Joseph AM, Beaver TM, Smith BK, Martin TD, Berg K, Hess PK, Deoghare HV, Leeuwenburgh, C. Effect of intermittent phrenic nerve stimulation during cardiothoracic surgery on mitochondrial respiration in the human diaphragm. Critical Care. 2014; 42(2): e152-6. PMID: 24126442. PMC3947040
Smith BK, Gabrielli A, Davenport PW, Martin AD. Effect of Training on Inspiratory Load Compensation in Weaned and Unweaned Mechanically Ventilated ICU Patients. Respiratory Care. 2014: 59(1): 22-31. PMID: 23764858. PMC4157996.
Mah CS, Soustek MS, Todd AG, McCall A, Smith BK, Corti M, Falk DJ, Byrne BJ. Adeno-Associated Virus-Mediated Gene Therapy for Metabolic Myopathy. Human Gene Therapy. 2013; 24(11): 928-36. PMID: 24164240. PMCID: PMC3814817.
Fuller DD, Elmallah M, Smith BK, Corti M, Lawson LA, Falk DJ, Byrne BJ. The Respiratory System in Pompe Disease. Resp Physiol Neurobiol. 2013; 189(2): 241-9. PMID: 23797185. PMC4083814.
Martin AD, Smith BK, Gabrielli, A. Mechanical ventilation, diaphragm weakness and weaning: a rehabilitation perspective. Resp Physiol Neurobiol. 2013; 189(2): 377-83. PMID: 23692928. PMC3808482.
Smith BK, Mah CS, Martin AD, Lawson LA, Conlon TJ, Clement N, Islam S, Dobjia N, Collins SW, Byrne BJ. Phase I/II trial of AAV1-GAA gene therapy to the diaphragm for chronic respiratory failure in Pompe disease: initial safety and ventilatory outcomes. Human Gene Therapy, 2013; 24(6): 630-40. PMID: 23570273. PMCID: PMC3689178.
Smith BK, Bleiweis MS, Neel C, Martin AD. Inspiratory Muscle Strength Training in Infants with Congenital Heart Disease and Prolonged Mechanical Ventilation: Case Report. Physical Therapy. 2013; 93(2): 229-36. PMID: 22466028. PMC3563028.
Smith BK, Martin AD, Vandenborne K, Darragh BD, Davenport PW. Chronic intrinsic transient tracheal occlusion elicits diaphragm remodeling in conscious rodents. PLoS One. 2012; 7(11): e29624. PMID: 23133678. PMCID: PMC3486807
Goddard MA, Mitchell EL, Smith BK, Childers MK. Establishing Clinical End Points of Respiratory Function in Large Animals for Clinical Translation. Physical Medicine and Rehabilitation Clinics of North America, 2012; 23(1): 75-94. PMID: 22239876.
Huang T, Deoghare HV, Smith BK, Beaver TM, Baker HV, Martin AD. Gene Expression Changes in the Human Diaphragm Following Cardiothoracic Surgery. Journal of Thoracic and Cardiovascular Surgery. 2011; 142(5): 1214-22. PMID: 21463877.
Byrne BJ, Falk DJ, Pacak CA, Nayak S, Hersog RW, Elder ME, Collins SW, Conlon TJ, Clement N, Cleaver BD, Cloutier DA, Porvasnik SL, Islam S, Elmallah MK, Martin A, Smith BK, Fuller DD, Lawson LA, Mah CS. Pompe disease gene therapy. Human Molecular Genetics. 2011; 20(R1): R61-8. PMID: 21518733. PMCID: PMC3095055.
Edwards TM, Smith BK, Watts DL, Germain-Aubrey CC, Roark A, Bybee S, Cox CE, Hamlin HJ, Guillette LJ. Group-Advantaged Training of Research (G.A.T.O.R.): A Metamorphosis of Mentorship. Bioscience. 2011; 61(4): 301-311. DOI: 10.1525/bio.2011.61.4.10.
Martin AD, Smith BK, Davenport PW, Harman E, Gonzalez-Rothi R, Baz M, Layon J, Banner M, Caruso L, Deoghare H, Huang T, Gabrielli A. Inspiratory muscle strength training improves weaning outcome in failure to wean patients: A controlled trial. Critical Care. 2011; 15(2): R84. PMID: 21385346.
Smith BK, Bleiweis MS, Zauhar J, Martin AD. Inspiratory Muscle Training in a Child with Nemaline Myopathy and Organ Transplantation. Pediatric Critical Care Medicine, 2011; 12(2): e94-8. PMID: 20407395. PMCID: PMC3633211.
Smith BK. A Pilot Study Evaluating Therapist-Nurse Inter-Rater Reliability of Dionne’s Egress Test in Morbidly Obese Patients. Acute Care Perspectives, 2008; 17(4): 1-7. ISSN: 1551-9147.
Kellerman BA, Martin D, Davenport PW. Inspiratory Strengthening Effect on Resistive Load Detection and Magnitude Estimation. Medicine and Science in Sports and Exercise. 2000; 32(11): 1859-1867. PMID: 11079514
