The center brings together faculty investigators and other personnel with a mission to study the molecular basis of human disease and its treatment as they relate to genomic variation, leading to personalized medicine. These endeavors utilize genomic information from patients and/or experimental systems. The goals of such investigations are to harness genomic information and its variation in humans or experimental systems to: 1) devise methods to tailor medical care for prediction of disease rise, prognosis, and treatment and 2) to identify novel pathways relevant to mechanism of disease and drug targets.