Research Terms
Biological Models Cell Biology Genetics DNA Sequencing Molecular Genetics Mutagenics Pathobiology Cardiology Drug Therapy Arrhythmia Cardiomyopathies Hereditary Diseases Muscular Dystrophy Cardiovascular Pharmacology Laboratory or Test Facilities
Keywords
Cardiomyopathy Ion Channels Lmna Long Qt Syndrome
Industries
4. Chen J, Liu Z, Creagh J, Zheng R, McDonald TV. Physical and Functional Interaction Sites in Cytoplasmic Domains of KCNQ1 and KCNE1 Channel Subunits. Am J Physiol Heart Circ Physiol. 2020 Feb 1;318(2):H212-H222. PMID: 31834838
5. Muller RD, McDonald T, Pope K, Cragun D. Evaluation of Clinical Practices Related to Variants of Uncertain Significance Results in Inherited Cardiac Arrhythmia and Inherited Cardiomyopathy Genes. Circ Genom Precis Med. 2020 June 10 doi:10.1161/CIRCGEN.119.002789 PMID: 32522017
6. Abouassali O, Chang M, Chidipi B, Martinez JL, Reiser M, Kanithi M, Soni R, McDonald TV, Herweg B, Saiz J, Calcul L, Noujaim SF. In vitro and in vivo cardiac toxicity of flavored electronic nicotine delivery systems. Am J Physiol Heart Circ Physiol. Am J Physiol Heart Circ Physiol. 2021 Jan 1;320(1):H133-H143. doi: 10.1152/ajpheart.00283.2020. Epub 2020 Nov 20. PMID: 33216635
7. Odgis JA, Gallagher KM, Suckiel SA, Donohue KE, Ramos MA, Kelly NR, Bertier G, Blackburn C, Brown K, Fielding L, Lopez J, Aguiniga KL, Maria E, Rodriguez JE, Sebastin M, Teitelman N, Watnick D, Yelton NM, Abhyankar A, Abul-Husn S, Baum A, Bauman LJ, Beal JC, Bloom T, Cunningham-Rundles C, Diaz GA, Dolan S, Ferket BS, Jobanputra V, Kovatch P, McDonald TV, McGoldrick PE, Rhodes R, Rinke ML, Robinson M, Rubinstein A, Shulman LH, Stolte C, Wolf SM, Yozawitz E, Zinberg RE, Greally JM, Gelb BD, Horowitz CR, Wasserstein MP, Kenny EE. The NYCKidSeq project: study protocol for a randomized controlled trial incorporating genomics into the clinical care of diverse New York City children. Trials. 2021 Jan 14;22(1):56. doi: 10.1186/s13063-020-04953-4. Erratum in: Trials. 2021 Feb 16;22(1):146. PMID: 33446240; PMC7807444. https://doi.org/10.1186/s13063-020-04953-4
8. Najari Beidokhti M, Bertalovitz A, Ji W, McCormack J, Jefferies L, Sempou E, Khokha MK, McDonald TV*, Lakhani SA*. Functional testing for variant prioritization in a family with Long QT syndrome. Mol Genet Genomics. 2021. 296:p. 823-836. PMID: 33876311 (*co-corresponding authors). https://doi.org/10.1007/s00438-021-01780-3
9. Argenziano MA, Burgos Angulo M, Beidokhti MN, Yang J, Bertalovitz AC, McDonald TV. Generation of a heterozygous FLNC mutation-carrying human iPSC line, USFi002-A, for modeling dilated cardiomyopathy. Stem Cell Res. 2021. 53:p. 102394 PMID: 34088019 https://doi.org/10.1016/j.scr.2021.102394
10. Yang J, Burgos Angulo M, Argenziano MA, Bertalovitz A, Beidokhti MN, McDonald TV. Generation of an iPSC cell line (USFi003-A) from a patient with dilated cardiomyopathy carrying a heterozygous mutation in LMNA (p.R541C). Stem Cell Res. 2021. 54:p. 102396 PMID: 34029931. https://doi.org/10.1016/j.scr.2021.102396
11. Angulo Burgos M, Yang J, Argenziano MA, Bertalovitz A, Beidokhti MN, McDonald TV. Generation of a Friedreich’s Ataxia patient-derived iPSC line USFi001-A. Stem Cell Res. 2021. 54: p. 102399. PMID: 34034220. https://doi.org/10.1016/j.scr.2021.102399
12. Yang J, Samal E, Burgos Angulo M, Bertalovitz A, McDonald TV. Generation of an arrhythmogenic right ventricular cardiomyopathy derived iPSC cell line (USFi004-A) carrying a heterozygous mutation in PKP2 (c.1799delA). Stem Cell Res, 2021. 54: p. 102398. 102398. PMID: 34034221. https://doi.org/10.1016/j.scr.2021.102398
13. Yang J, Burgos Angulo M, Argenziano MA, Bertalovitz A, Beidokhti MN, McDonald TV. Phenotypic Variability in iPSC-induced Cardiomyocytes and Cardiac Fibroblasts Carrying Diverse LMNA Mutations. Frontiers in Physiology, section Cardiac Electrophysiology 2021. 12: 778982. PMID: 34975533. PMCID: PMC8716763, DOI: 10.3389/fphys.2021.778982
14. Chidipi B, Burgos Angulo M, Shah SI, Rieser M, Ullah G, McDonald TV, Noujaim SF. The Dynamin-Related Protein 1 is Decreased and the Mitochondrial Network is Altered in Friedreich’s Ataxia Cardiomyopathy. International Journal of Biochemistry and Cell Biology 2021. 143:106137. PMID: 34923139 (Accepted). https://doi.org/10.1016/j.biocel.2021.106137
American Heart Association, Fellow; 2011 - present
| Director |
Thomas McDonald |
| Phone | 813-396-9713 |
| Website | https://health.usf.edu/medicine/heart-institute |
| Mission | Establish a multidisciplinary research unity which will increase USF research productivity, research funding, and national research presence. |
University of South Florida 4202 E. Fowler Avenue MDD 610C Tampa, FL 33620
