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Non-Invasive Sensor for Determining Blood-Sugar Levels in Diabetics and Characterizing Materials


Researchers at the University of Centraal Florida have developed a non-invasive sensor for monitoring a patient's various parameters, such as glucose concentrations. With the invention, patients could monitor themselves intermittently or continuously, without the need to painfully withdraw blood or perform complex chemical tests. Several electrochemical methods determine blood glucose concentration, but all require collecting a small blood sample. Optical sensing methods do not require collecting biological samples, allowing them to operate as truly non-invasive techniques, but such methods undergo significant interferences hindering an accurate reading. In samples, such as blood, which contain one or more components with different refractive indices, it may be difficult to obtain useful information. Prior methods, such as infrared absorption spectroscopy, have failed to obtain an analyte's (solvent, glucose or drug) concentration directly from its absorption spectrum within a sample due to strong scattering. Therefore, there is a need to develop a method in which the scattering influence is isolated from the absorption coefficients in a variety of materials.

Technical Details

The invention characterizes optically dense materials using an integrated optical sensor by independently determining the scattering and absorption coefficients for the materials. This novel sensor is based on low coherence interferometry and can be used as a non-invasive, fast, and inexpensive instrument for measuring the concentration of glucose in the skin. It can also be used to characterize tissues such as arteries and other organs during endoscopic procedures. Finally, it can be used for the characterization of complex composite materials in a variety of coating and material science applications.


  • Fast, non-invasive, real-time monitoring of blood glucose concentration
  • Eliminates the pain and discomfort of finger-pricking
  • Improves accuracy of the sensor while decreasing its manufacturing cost
  • Minimizes the possibility of interference and scattering complications
  • Market Application

  • Non-invasive glucose sensor
  • Research Terms: Technology > Instruments > Medical Instrumentation
    Keywords: Healthcare, Medical Devices;
    Technology Inventors: Aristide Dogariu
    Technology Information URL:
    University: University of Central Florida
    Tech Transfer URL:

    Associated Patents

    Patent Name: Interferometric sensor for characterizing materials
    Patent Number: US Patent 7,307,734
    Patent Status: Issued
    Issue Date: December 11, 2007
    Patent Record: View full record at google patents
    View full record at United States Patent and Trademark Office
    Patent Inventors:
    Aristide Dogariu

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