A team of USF researchers is studying possible links between Long COVID and dementia and Alzheimer’s disease. In previous work, Subhra Mohapatra and fellow researchers found that Long COVID produces tau – an accumulation of neurotoxic molecules that creates aggregates known as tauopathy. This leads to memory loss and loss of cognition, hallmarks of Alzheimer’s.
Now the team aims to understand the cellular and molecular mechanisms behind COVID-induced tauopathy and identify potential drug targets to prevent or slow its progression. The goal is to help prepare for the danger that Long COVID could lead to a wave of early onset Alzheimer’s disease in 10 years.
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