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Joseph Larkin

Associate Professor

AG-MICROBIOLOGY / CELL SCI | COLLEGE- AGRICUL / NAT RES

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Research Terms & Keywords

Research Terms

Endocrine Diseases Immunologic Diseases Lymphatic System Diseases

Research Projects

Ends

Title

01-2024

Human milk antibody response to COVID-19 vaccination and protection to breastfeeding infants Human milk antibody response to COVID-19 vaccination and protection to breastfeeding infants

GERBER FOUNDATION

12-2023

SBT-100 Regulation of Cytokine Signaling and Autoimmunity SBT-100 Regulation of Cytokine Signaling and Autoimmunity

SINGH BIOTECHNOLOGY

12-2023

Mitigation of Equine Recurrent Uveitis through topical suppressor of Cytokine Signaling-1 mimetic peptide Mitigation of Equine Recurrent Uveitis through topical suppressor of Cytokine Signaling-1 mimetic peptide

GRAYSON JOCKEY CLUB RES FO

12-2023

Mitigation of Equine Recurrent Uveitis through Topical Application of Suppressor of Cytokine Signaling Mimetic Peptide-Pilot Mitigation of Equine Recurrent Uveitis through Topical Application of Suppressor of Cytokine Signaling Mimetic Peptide-Pilot

HHMD LLC

10-2022

Function and protein cargo of exosomes in antigen presenting cells during Salmonella infection Function and protein cargo of exosomes in antigen presenting cells during Salmonella infection

NATL INST OF HLTH NIAI

08-2021

OR-DRPD-ROF2018: Identification of the first extracellular nicotinamide adenine dinucleotide-binding receptor in animal cells OR-DRPD-ROF2018: Identification of the first extracellular nicotinamide adenine dinucleotide-binding receptor in animal cells

UF OFFICE OF RESEARCH

04-2020

SBIR: Biomaterial-Based Delivery of Suppressor of Cytokine Signaling Mimetics to Ameliorate Type 1 Diabetes SBIR: Biomaterial-Based Delivery of Suppressor of Cytokine Signaling Mimetics to Ameliorate Type 1 Diabetes

NATL INST OF HLTH NIDD

04-2020

ONEVAX

08-2018

2018 National Psoriasis Foundation Summer Student Research Grant 2018 National Psoriasis Foundation Summer Student Research Grant

National Psoriasis Foundation

05-2018

Therapeutic Administration of Suppressor of Cytokine Signaling Mimetics to Ameliorate Type 1 Diabetes Therapeutic Administration of Suppressor of Cytokine Signaling Mimetics to Ameliorate Type 1 Diabetes

NATL INST OF HLTH NIAI

05-2018

ONEVAX

12-2017

Inhibition of Psoriasis through Suppressor of Cytokine Signaling-1 Regulation Inhibition of Psoriasis through Suppressor of Cytokine Signaling-1 Regulation

National Psoriasis Foundation

09-2017

Separating the Signal from the Noise in the Autoimmune Microbiome for Type 1 Diabetes: Introducing the Post-metagenomics era Separating the Signal from the Noise in the Autoimmune Microbiome for Type 1 Diabetes: Introducing the Post-metagenomics era

JUVENILE DIABETES FO

08-2017

AAI CAREERS IN IMMUNOLOGY FELLOWSHIP AAI CAREERS IN IMMUNOLOGY FELLOWSHIP

AM ASSN OF IMMUNOLOGISTS

12-2016

Modulation of T lymphocyte plasticity and autoimmune effector functions through suppressor of cytokine signaling regulation (SOCS) Modulation of T lymphocyte plasticity and autoimmune effector functions through suppressor of cytokine signaling regulation (SOCS)

BENAROYA RES INST AT VA MASO

12-2016

NATL INST OF HLTH NIAI

08-2016

Clinical and Translational Science Institute Clinical and Translational Science Institute

UF RESEARCH FO

12-2015

Regulation of SLE Through SOCS1 Mimetic Peptides Regulation of SLE Through SOCS1 Mimetic Peptides

LUPUS RES INS

11-2014

Regulation of T1D onset through gut flora mediated T cel Regulation of T1D onset through gut flora mediated T cel

JUVENILE DIABETES FO

08-2014

STEM Ladder Grant STEM Ladder Grant

MIAMI DADE COMMUNITY COLLEGE

02-2014

Study of Gamma Interferon Agonists Mimetics Study of Gamma Interferon Agonists Mimetics

NATL INST OF HLTH NIAI

08-2013

STEM Ladder Grant STEM Ladder Grant

MIAMI DADE COMMUNITY COLLEGE

08-2012

STEM Ladder Grant STEM Ladder Grant

MIAMI DADE COMMUNITY COLLEGE

06-2012

Direct replication of T cell receptors specific for type Direct replication of T cell receptors specific for type

UNIV OF COLORAD

04-2012

The defining characteristics of the autoimmune microbiom The defining characteristics of the autoimmune microbiom

UF DIV OF SPONSORED RESEARC

12-2010

JDRF-BRI Center for Translational Research: Repertoire A JDRF-BRI Center for Translational Research: Repertoire A

UNIV OF COLORAD

08-2009

Dynamic Survey of T Cell Repertoire Targeting Pancreatic Dynamic Survey of T Cell Repertoire Targeting Pancreatic

UNIV OF COLORAD

Degrees

Ph.D., Immunology

University of Florida ▪ 2000
B.S., Microbiology

University of Florida ▪ 1996

Publications

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More Publications

1) Lau K., Benitez P., Ardissone A., Wilson T., Collins EL., Lorca G., Li N., Sankar D., Wasserfall C., Neu J., Atkinson MA., Shatz DA., Triplett EW., and Larkin J 3^rd (2011) Inhibition of Type 1 Diabetes Correlated to a Lactobacillus johnsonii N6.2 Mediated Th17 Bias. J. Immunol. 186(6): 3538-46.

2) Jager LD., Dabelic R., Waiboci LW., Lau K., Haider SM., Ahmed CMI., Larkin J 3^rd., David D., and Johnson HM. (2011) The Kinase Inhibitory Region of SOCS-1 is Sufficient to Inhibit T helper-17 Function in Experimental Allergic Encephalomyelitis. J. Neuroimmunol. 232(1-2): 108-18.

3) Valladares R., Sankar D., Li N., Williams E., Lai KK., Abdelgeliel AS., Gonzalez CF., Wasserfall CH., Larkin J 3^rd., Schatz D., Atkinson MA., Triplett EW., Neu J., and Lorca GL (2010) Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats. PLoS One. 5(5):e10507.

4) BD, Fields ML., Nish SA., Larkin J 3^rd, Caton AJ., and Erikson J (2008) Autoantibody production in lpr/lpr gld/gld mice reflects accumulation of CD4+ effector cells that are resistant to regulatory T cell activity. J Autoimmun. doi:10.1016/j.jaut2008.04.022.

5) Larkin J 3^rd, Rankin AL., Picca CC., Riley MP., Jenks SA., Sant AJ., and Caton AJ. (2008) CD4+CD25+ regulatory T cell repertoire formation shaped by differential presentation of peptides from a self-antigen. J Immunol. 180(4):2149-57.

6) Rankin AL., Reed AJ., Oh S., Picca CC., Guay HM., Larkin J 3^rd., Aitken MK., Panarey L., Koeberlein B., Lipsky P., Tomaszewski JE., Naji A., and Caton AJ. (2008) CD4+ T cells recognizing a single self-peptide expressed by APC’s induce spontaneous autoimmune arthritis. J Immunol. 180(2): 833-41.

7) Guay HM., Larkin J 3^rd, Picca CC., and Caton AJ. (2007) Spontaneous auto-reactive memory B cell formation driven by a high frequency of auto-reactive CD4+ T cells. J Immunol. 178(8):4793-802.

8) Larkin J 3^rd, Picca CC., and Caton AJ. (2007) Activation of CD4+CD25+ regulatory T cell suppressor function by analogs of the selecting peptide. Eur J Immunol. 37(1): 139-46.

Memberships

American Association of Immunologists, Member; 2007 - present

Network of Minority Research Investigators, Member; 2007 - present

Professional Presentations

Antigen Presenting Cell Interactions with Gut Flora Modulate Diabetogenic T lymphocyte Effector Functions; Scientific Conference; Keystone Symposium; 2013