Research Terms
Keywords
Beta Cell Regeneration Diabetes Pancreas Single-Cell Rna-Seq
Industries
• D Avrahami, YJ Wang, J Schug, E Feleke, L Gao, C Liu, A Naji, B Glaser, KH Kaestner, HPAP Consortium. Single-cell transcriptomics of human islet ontogeny defines the molecular basis of ?-cell dedifferentiation in T2D. Molecular Metabolism, 2020; 42:101057.
• AM Zahm, AW Wang, YJ Wang, J Schug, KJ Wangensteen, KH Kaestner. A High-Content Screen Identifies MicroRNAs That Regulate Liver Repopulation After Injury in Mice. Gastroenterology, 2020;158(4):1044-1057.
• AW Wang, YJ Wang, AM Zahm, AR Morgan, KJ Wangensteen, KH Kaestner. The Dynamic Chromatin Architecture of the Regenerating Liver. Cellular and Molecular Gastroenterology and Hepatology, 2020;9(1):121-143.
• YJ Wang, J Schug, J Lin, Z Wang, A Kossenkov, HPAP consortium, KH Kaestner. Comparative analysis of commercially available single-cell RNA sequencing platforms for their performance in complex human tissues. bioRxiv, 2019.
• YJ Wang, D Traum, J Schug, L Gao, C Liu, HPAP consortium, MA Atkinson, AC Powers, MD Feldman, A Naji, KM Chang, KH Kaestner. Multiplexed in situ imaging mass cytometry analysis of the human endocrine pancreas and immune system in type 1 diabetes. Cell Metabolism, 2019; 29(3): 769-783.
• YJ Wang, KH Kaestner. Single-Cell RNA-Seq of the Pancreatic Islets––a Promise Not yet Fulfilled? Cell Metabolism, 2019.
• M Shoshkes-Carmel, YJ Wang, KJ Wangensteen, B Tóth, A Kondo, S Itzkovitz, KH Kaestner. Subepithelial telocytes are an important source of Wnts that support intestinal crypts. Nature, 2018; 557: 242-246.
• KJ Wangensteen, YJ Wang, Z Dou, AW Wang, E Mosleh-Shirazi, MA Horlbeck, LA Gilbert, JS Weissman, SL Berger, KH Kaestner. Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform. Hepatology, 2017.
• YJ Wang, ML Golson, J Schug, D Traum, C Liu, K Vivek, C Dorrell, A Naji, AC Powers, KM Chang, M Grompe, KH Kaestner. Single-cell mass cytometry analysis of the human endocrine pancreas. Cell Metabolism, 2016; 24(4): 616-626. Cover story.
• YJ Wang, J Schug, KJ Won, C Liu, A Naji, D Avrahami, ML Golson, KH Kaestner. Single cell transcriptomics of the human endocrine pancreas. Diabetes, 2016; 65(10): 3028-3038.
• YJ Wang, JT Park, MJ Parsons, SD Leach. Fate mapping of ptf1a-expressing cells during pancreatic organogenesis and regeneration in zebrafish. Developmental Dynamics, 2015; 244(6): 724-735.
• YJ Wang, F McAllister, JM Bailey, SG Scott, AM Hendley, SD Leach, B Ghosh. Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia. PLoS One, 2014; 9(11): e113127.
• YJ Wang, J Bailey, M Rovira, SD Leach. Sphere-forming assays for assessment of benign and malignant pancreatic stem cells. Pancreatic Cancer: Methods in Molecular Biology, 2013.
