-
"Scalable lipid droplet microarray fabrication, validation, and screening"
2024 ▪
PLoS ONE
-
"ORF45, a multifunctional immediate early and tegument protein of KSHV"
2023 ▪
Journal of Medical Virology
-
"The Dengue virus protease NS2B3 cleaves cyclic GMP-AMP synthase to suppress cGAS activation"
2023 ▪
Journal of Biological Chemistry
-
"Structural basis of higher order oligomerization of KSHV inhibitor of cGAS"
2022 ▪
Proceedings of the National Academy of Sciences
-
"KSHV-encoded ORF45 activates human NLRP1 inflammasome"
2022 ▪
Nature Immunology
Fanxiu Zhu;
Qiming Liang;
Xing Yang;
Jingfan Zhou;
Chengrong Liu;
Yafei Qu;
Weili Wang;
Maggie Z. X. Xiao;
Zhenshan Liu;
-
"The SUMO E3 ligase activity of ORF45 determines KSHV lytic replication"
2022 ▪
PLoS Pathogens
Fanxiu Zhu;
Qiming Liang;
Hongying Deng;
Chengrong Liu;
Maggie Z. X. Xiao;
Zhenshan Liu;
Xin Wang;
Wenshu Li;
Xiaoqian Wang;
Xue Xu;
Chunxia Wang;
Yucai Zhang;
Joyce Fu;
-
"A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host"
2022 ▪
Nature Communications
Fanxiu Zhu;
Ersheng Kuang;
Anita Alexa;
Péter Sok;
Fridolin Gross;
Krisztián Albert;
Evan Kobori;
Ádám L. Póti;
Gerg? Gógl;
Isabel Bento;
Susan S. Taylor;
Andrea Ciliberto;
Attila Reményi;
-
"RSK1 SUMOylation is required for KSHV lytic replication"
2021 ▪
PLoS Pathogens
Wenwei Li;
Fanxiu Zhu;
Qiming Liang;
Jingfan Zhou;
Chengrong Liu;
Maggie Z. X. Xiao;
Zhenshan Liu;
Xin Wang;
Chunxia Wang;
Yucai Zhang;
Joyce Fu;
Peixian Dong;
-
"Disruption of the Interaction between ORF33 and the Conserved Carboxyl-Terminus of ORF45 Abolishes Progeny Virion Production of Kaposi Sarcoma-Associated Herpesvirus"
2021 ▪
Viruses
-
"Cooperative DNA binding mediated by KicGAS/ORF52 oligomerization allows inhibition of DNA-induced phase separation and activation of cGAS"
2021 ▪
Nucleic Acids Research
Qian Yin;
Yuan Tian;
Jian-jun Wu;
Siming Ma;
Fanxiu Zhu;
Debipreeta Bhowmik;
Mingjian Du;
Zhijian Chen;
-
"Evasion of Intracellular DNA Sensing by Human Herpesviruses"
2021 ▪
Frontiers in Cellular and Infection Microbiology
-
"Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome"
2019 ▪
Frontiers in Microbiology
Fanxiu Zhu;
Lielian Zuo;
Yan Xie;
Shuyu Xin;
Lingzhi Liu;
Jianhong Lu;
Wenxing Yue;
Shujuan Du;
Jing Yang;
Jingjin Hu;
Jing Zhang;
Pengfei Cao;
-
"Targeting Exosomal EBV-LMP1 Transfer and miR-203 Expression via the NF-?B Pathway: The Therapeutic Role of Aspirin in NPC"
2019 ▪
Molecular Therapy — Nucleic Acids
Fanxiu Zhu;
Lielian Zuo;
Yan Xie;
Jinyong Tang;
Shuyu Xin;
Lingzhi Liu;
Siwei Zhang;
Qijia Yan;
Jianhong Lu;
-
"A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1"
2019 ▪
Nature
Fanxiu Zhu;
Baoyu Zhao;
Fenglei Du;
Pengbiao Xu;
Chang Shu;
Banumathi Sankaran;
Samantha L. Bell;
Mengmeng Liu;
Yuanjiu Lei;
Xinsheng Gao;
Xiaofeng Fu;
Yang Liu;
Arthur Laganowsky;
Xueyun Zheng;
Jun-Yuan Ji;
A. Phillip West;
Robert O. Watson;
Pingwei Li;
-
"Early Pattern of Epstein-Barr Virus Infection in Gastric Epithelial Cells by “Cell-in-cell”"
2019 ▪
Virologica Sinica
Fanxiu Zhu;
Lielian Zuo;
Yan Xie;
Shuyu Xin;
Lingzhi Liu;
Siwei Zhang;
Jianhong Lu;
Wenxing Yue;
Meijuan Zhu;
Jing Zhang;
Shen Li;
Wei Dang;
-
"Development of an ORF45-Derived Peptide To Inhibit the Sustained RSK Activation and Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus"
2019 ▪
Journal of Virology
Fanxiu Zhu;
Ersheng Kuang;
Xiaojuan Li;
Lu Huang;
Yunjun Xiao;
Xiangyang Yao;
Xubing Long;
-
"Sirtuin 6 Attenuates Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Suppressing Ori-Lyt Activity and Expression of RTA"
2019 ▪
Journal of Virology
Paul Wang;
Wenwei Li;
Fanxiu Zhu;
Qiyi Tang;
Min Hu;
Najealicka Armstrong;
Edward Seto;
-
"The interactome of EBV LMP1 evaluated by proximity-based BioID approach"
2018 ▪
Virology
Fanxiu Zhu;
Lauren A. Howell;
David G Meckes;
Xia Liu;
Mark A Rider;
Mujeeb R Cheerathodi;
Stephanie N Hurwitz;
Dingani Nkosi;
Deanna C Tremblay;
-
"Correction for Avey et al., “Discovery of a Coregulatory Interaction between Kaposi's Sarcoma-Associated Herpesvirus ORF45 and the Viral Protein Kinase ORF36”"
2017 ▪
Journal of Virology
Wenwei Li;
Denis Avey;
Joseph Gillen;
Fanxiu Zhu;
Sarah C. Ogden;
Sarah Tepper;
Benjamin Pifer;
Amritpal Bahga;
Hunter Williams;
-
"Extracellular vesicles: novel vehicles in herpesvirus infection"
2017 ▪
Virologica Sinica
Fanxiu Zhu;
Lielian Zuo;
Lingzhi Liu;
Jianhong Lu;
Quan Zhou;
Yan Xie;
-
"Discovery of a Coregulatory Interaction between Kaposi's Sarcoma-Associated Herpesvirus ORF45 and the Viral Protein Kinase ORF36"
2016 ▪
Journal of Virology
Wenwei Li;
Denis Avey;
Joseph Gillen;
Fanxiu Zhu;
Sarah C. Ogden;
Sarah Tepper;
Benjamin Pifer;
Amritpal Bahga;
Hunter Williams;
-
"Kaposi's Sarcoma-Associated Herpesvirus Inhibitor of cGAS (KicGAS), Encoded by ORF52, Is an Abundant Tegument Protein and Is Required for Production of Infectious Progeny Viruses"
2016 ▪
Journal of Virology
Jian-jun Wu;
Wenwei Li;
Denis Avey;
Siming Ma;
Fanxiu Zhu;
Bishi Fu;
Xia Liu;
-
"Melioidosis acquired by a traveler from Papua New Guinea"
2016 ▪
Travel Medicine and Infectious Disease
Fanxiu Zhu;
Z. Kong;
Y. Fang;
M. Zhang;
J. Hong;
Z. Tan;
Z. Yuan;
X. Mao;
Z. Jin;
Y. Zhu;
J. Chen;
-
"Hierarchical regulation of the genome: global changes in nucleosome organization potentiate genome response"
2016 ▪
Oncotarget
-
"Mono-ubiquitylated ORF45 Mediates Association of KSHV Particles with Internal Lipid Rafts for Viral Assembly and Egress"
2015 ▪
PLoS Pathogens
Wenwei Li;
Fanxiu Zhu;
Yan Yuan;
Xin Wang;
Nannan Zhu;
Yan Wang;
-
"ORF33 and ORF38 of Kaposi's Sarcoma-Associated Herpesvirus Interact and Are Required for Optimal Production of Infectious Progeny Viruses"
2015 ▪
Journal of Virology
Jian-jun Wu;
Wenwei Li;
Denis Avey;
Joseph Gillen;
Wendell Miley;
Denise Whitby;
Fanxiu Zhu;
Bishi Fu;
-
"Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein"
2015 ▪
Cell Host & Microbe
Hong Li;
Jian-jun Wu;
Wenwei Li;
Yaming Shao;
Denis Avey;
Bishi Fu;
Joseph Gillen;
Travis Hand;
Siming Ma;
Xia Liu;
Wendell Miley;
Andreas Konrad;
Frank Neipel;
Michael Stürzl;
Denise Whitby;
Fanxiu Zhu;
-
"Phosphoproteomic Analysis of KSHV-Infected Cells Reveals Roles of ORF45-Activated RSK during Lytic Replication"
2015 ▪
PLoS Pathogens
Wenwei Li;
Denis Avey;
Fanxiu Zhu;
Sarah Tepper;
Zachary Turpin;
-
"ORF45-Mediated Prolonged c-Fos Accumulation Accelerates Viral Transcription during the Late Stage of Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus"
2015 ▪
Journal of Virology
Denis Avey;
Fanxiu Zhu;
Xiaojuan Li;
Ersheng Kuang;
Shumin Du;
Yuqing Li;
-
"Recent advances in the study of Kaposi’s sarcoma-associated herpesvirus replication and pathogenesis"
2015 ▪
Virologica Sinica
-
"Erratum for Fu et al., Activation of p90 Ribosomal S6 Kinases by ORF45 of Kaposi's Sarcoma-Associated Herpesvirus Is Critical for Optimal Production of Infectious Viruses"
2015 ▪
Journal of Virology
Wenwei Li;
Denis Avey;
Fanxiu Zhu;
Ersheng Kuang;
Bishi Fu;
Jinjong Myoung;
Zachary Turpin;
Ahmed Valdes;
Kevin Brulois;
Xiaojuan Li;
-
"A Survey of the Interactome of Kaposi's Sarcoma-Associated Herpesvirus ORF45 Revealed Its Binding to Viral ORF33 and Cellular USP7, Resulting in Stabilization of ORF33 That Is Required for Production of Progeny Viruses"
2015 ▪
Journal of Virology
Jian-jun Wu;
Wenwei Li;
Denis Avey;
Joseph Gillen;
Fanxiu Zhu;
Qiming Liang;
Fayi Wu;
Jinjong Myoung;
-
"Activation of p90 Ribosomal S6 Kinases by ORF45 of Kaposi's Sarcoma-Associated Herpesvirus Is Critical for Optimal Production of Infectious Viruses"
2014 ▪
Journal of Virology
Wenwei Li;
Denis Avey;
Fanxiu Zhu;
Xiaojuan Li;
Ersheng Kuang;
Bishi Fu;
Jinjong Myoung;
Zachary Turpin;
Ahmed Valdes;
Kevin Brulois;
-
"Changes in nucleosome occupancy occur in a chromosome specific manner"
2014 ▪
Genomics Data
-
"The spring-loaded genome: Nucleosome redistributions are widespread, transient, and DNA-directed"
2013 ▪
Genome Research
-
"ORF45 of Kaposi's Sarcoma-Associated Herpesvirus Inhibits Phosphorylation of Interferon Regulatory Factor 7 by IKK? and TBK1 as an Alternative Substrate"
2012 ▪
Journal of Virology
Bishi Fu;
Fanxiu Zhu;
Yan Yuan;
Qiming Liang;
Xiaojuan Li;
Fayi Wu;
-
"Phosphorylation of Eukaryotic Translation Initiation Factor 4B (EIF4B) by Open Reading Frame 45/p90 Ribosomal S6 Kinase (ORF45/RSK) Signaling Axis Facilitates Protein Translation during Kaposi Sarcoma-associated Herpesvirus (KSHV) Lytic Replication"
2011 ▪
Journal of Biological Chemistry
Fanxiu Zhu;
Qiming Liang;
Ersheng Kuang;
Bishi Fu;
Jinjong Myoung;
-
"Tripartite Motif-Containing Protein 28 Is a Small Ubiquitin-Related Modifier E3 Ligase and Negative Regulator of IFN Regulatory Factor 7"
2011 ▪
The Journal of Immunology
Fanxiu Zhu;
Xianfang Wu;
Qiming Liang;
Hongying Deng;
Xiaojuan Li;
Qiyi Tang;
Tsung-Hsien Chang;
Hongzhuang Peng;
Frank J. Rauscher;
Keiko Ozato;
-
"Negative Regulator of IFN Regulatory Factor 7 Ubiquitin-Related Modifier E3 Ligase and Tripartite Motif-Containing Protein 28 Is a Small"
2011 ▪
Fanxiu Zhu;
Xianfang Wu;
Hongying Deng;
Xiaojuan Li;
Qiyi Tang;
Tsung-Hsien Chang;
Hongzhuang Peng;
Keiko Ozato;
-
"PROTEIN TRANSLATION DURING KSHV LYTIC REPLICATION"
2011 ▪
Fanxiu Zhu;
Qiming Liang;
Ersheng Kuang;
Bishi Fu;
Jinjong Myoung;
-
"the Cellular Integrated Stress Responses Cross-Regulation between the IFN Responses and Activating Transcription Factor 4 Suggests a Negative Regulation of IRF7 Activation by"
2011 ▪
Fanxiu Zhu;
Qiming Liang;
Hongying Deng;
Chiao-Wang Sun;
-
"Negative Regulation of IRF7 Activation by Activating Transcription Factor 4 Suggests a Cross-Regulation between the IFN Responses and the Cellular Integrated Stress Responses"
2010 ▪
The Journal of Immunology
Fanxiu Zhu;
Qiming Liang;
Hongying Deng;
Chiao-Wang Sun;
Tim M. Townes;
-
"Short-hairpin RNAs delivered by lentiviral vector transduction trigger RIG-I-mediated IFN activation"
2009 ▪
Nucleic Acids Research
Hengli Tang;
Rachael Kenworthy;
Fanxiu Zhu;
Feng Yang;
Diana Lambert;
Nan Wang;
Zihong Chen;
Haizhen Zhu;
Chen Liu;
Kui Li;
-
"Activation of RSK and ERK MAPK kinases by ORF45 of Kaposi's sarcoma-associated herpesvirus"
2009 ▪
Infectious Agents and Cancer
-
"Mechanism of Sustained Activation of Ribosomal S6 Kinase (RSK) and ERK by Kaposi Sarcoma-associated Herpesvirus ORF45"
2009 ▪
Journal of Biological Chemistry
-
"Identification of the Nuclear Export and Adjacent Nuclear Localization Signals for ORF45 of Kaposi's Sarcoma-Associated Herpesvirus"
2008 ▪
Journal of Virology
-
"Identification of the Nuclear Export and Adjacent Nuclear Localization Signals for ORF45 of Kaposi's"
2008 ▪
-
"Activation of p90 Ribosomal S6 Kinase by ORF45 of Kaposi's Sarcoma-Associated Herpesvirus and Its Role in Viral Lytic Replication"
2007 ▪
Journal of Virology
-
"Vertical trans mission of baculovirus and expression of baculovirus mediated green fluorescent protein gene in successive generations of Helicoverpa armigera"
2001 ▪
Kun Chong xue bao. Acta Entomologica Sinica
Fanxiu Zhu;
Yi-Peng Qi;
Liu Zu Qiang;
Yang Fu Hua;
Zhu Ying;
-
"A viral gene that activates lytic cycle expression of Kaposi’s sarcoma-associated herpesvirus"
1998 ▪
Proceedings of the National Academy of Sciences
Fanxiu Zhu;
Ren Sun;
Su-Fang Lin;
Lyndle Gradoville;
Yan Yuan;
George Miller;
-
"Expression of green fluorescent protein gene with baculovirus vector in insect cells"
1997 ▪
Wuhan University Journal of Natural Sciences
-
"A baculovirus vector derived from immediately early gene promoter of Autographa californica nuclear polyhedrosis virus"
1996 ▪
Journal of Virological Methods